Catalog No.
YHC86201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met210-Lys497
Predicted molecular weight
35.58 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11171
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Band 4.1, EPB4.1, Protein 4.1, 4.1R, EPB41, P4.1, E41P, Erythrocyte membrane protein band 4.1
In silico analysis of lncRNA-miRNA-mRNA signatures related to Sorafenib effectiveness in liver cancer cells., PMID:39839902
Identification of Novel Nexilin Splice Variants in Mouse and Human Tissues., PMID:39682766
Analysis of serum peptidome profiles of non-metastatic and metastatic feline mammary carcinoma using liquid chromatography-tandem mass spectrometry., PMID:38951817
Cytoskeletal Protein 4.1R in Health and Diseases., PMID:38397451
Novel mutation in alpha-spectrin gene in Saudi patients with hereditary spherocytosis., PMID:38319988
Molecular insights into hereditary elliptocytosis and pyropoikilocytosis: NGS uncovers multiple potential candidate genes., PMID:37400730
[Clinical and gene mutation characteristics of patients with hereditary ellipsocytosis: nine cases report and literature review]., PMID:37357001
Genome-wide analysis of dysregulated RNA-binding proteins and alternative splicing genes in keloid., PMID:36777722
Are EPB41 and alpha-synuclein diagnostic biomarkers of sport-related concussion? Findings from the NCAA and Department of Defense CARE Consortium., PMID:36403906
Splice variants denote differences between a cancer stem cell side population of EWSR1‑ERG‑based Ewing sarcoma cells, its main population and EWSR1‑FLI‑based cells., PMID:35088879
The protein 4.1R downregulates VEGFA in M2 macrophages to inhibit colon cancer metastasis., PMID:34717920
Circular RNA erythrocyte membrane protein band 4.1 assuages ultraviolet irradiation-induced apoptosis of lens epithelial cells by stimulating 5'-bisphosphate nucleotidase 1 in a miR-24-3p-dependent manner., PMID:34652259
Multifunctional protein 4.1R regulates the asymmetric segregation of Numb during terminal erythroid maturation., PMID:34364872
Clinical and molecular genetic analysis of a Chinese family with hereditary elliptocytosis caused by a novel mutation in the EPB41 gene., PMID:33942936
Corrigendum: Identification of a Two-Gene (PML-EPB41) Signature With Independent Prognostic Value in Osteosarcoma., PMID:33937083
Dysregulated healing responses in diabetic wounds occur in the early stages postinjury., PMID:33350981
EPB41 suppresses the Wnt/β-catenin signaling in non-small cell lung cancer by sponging ALDOC., PMID:33242559
Cytoskeleton protein 4.1R regulates B-cell fate by modulating the canonical NF-κB pathway., PMID:32852059
A novel EPB41 p.Trp704* mutation in a Korean patient with hereditary elliptocytosis: a case report., PMID:32807033
Detecting Prognosis Risk Biomarkers for Colon Cancer Through Multi-Omics-Based Prognostic Analysis and Target Regulation Simulation Modeling., PMID:32528533
To study the effect of oxygen carrying capacity on expressed changes of erythrocyte membrane protein in different storage times., PMID:32501470
A Novel α-Spectrin Pathogenic Variant in Trans to α-Spectrin LELY Causing Neonatal Jaundice With Hemolytic Anemia From Hereditary Pyropoikilocytosis Coexisting With Gilbert Syndrome., PMID:32287101
Silencing EPB41 Gene Expression Leads to Cell Cycle Arrest, Migration Inhibition, and Upregulation of Cell Surface Antigen in DC2.4 Cells., PMID:32157074
Identification of a Two-Gene (PML-EPB41) Signature With Independent Prognostic Value in Osteosarcoma., PMID:32039036
Cytoskeletal Protein 4.1R Is a Positive Regulator of the FcεRI Signaling and Chemotaxis in Mast Cells., PMID:31993060
[Identification of a Novel Mutation of EPB41 Gene in a Family Affected with Hereditary Elliptocytosis]., PMID:31950797
Cytoskeleton protein 4.1R suppresses murine keratinocyte cell hyperproliferation via activating the Akt/ERK pathway in an EGFR-dependent manner., PMID:31562860
Protein 4.1R negatively regulates CD8+ T-cell activation by modulating phosphorylation of linker for activation of T cells., PMID:31135971
Molecular diagnosis of hereditary spherocytosis by multi-gene target sequencing in Korea: matching with osmotic fragility test and presence of spherocyte., PMID:31122244
Expression of Protein 4.1 Family in Breast Cancer: Database Mining for 4.1 Family Members in Malignancies., PMID:31063460
KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia patient-specific induced pluripotent stem cells., PMID:30876823
[Clinical manifestations of erythrocyte membrane protein coding gene mutations in hereditary spherocytosis]., PMID:30486587
Lnc-EPB41-Protein Interactions Associated with Congenital Pouch Colon., PMID:30227690
[Construction of a stable 4.1R gene knockout cell model in RAW264.7 cells using CRISPR/Cas9 technique]., PMID:29292253
Protein 4.1R is Involved in the Transport of 5-Aminolevulinic Acid by Interaction with GATs in MEF Cells., PMID:28881432
Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating., PMID:28701737
Genetic Factors Involved in Mandibular Prognathism., PMID:28570402
Alternative polyadenylation in a family of paralogous EPB41 genes generates protein 4.1 diversity., PMID:27981895
Whole-exome sequencing analysis in twin sibling males with an anterior cruciate ligament rupture., PMID:27692106
Genotype-phenotype correlations in hereditary elliptocytosis and hereditary pyropoikilocytosis., PMID:27667160
Exome sequencing results in successful diagnosis and treatment of a severe congenital anemia., PMID:27551681
Integrative Functional Genomics Implicates EPB41 Dysregulation in Hepatocellular Carcinoma Risk., PMID:27453575
Detection of new pathogenic mutations in patients with congenital haemolytic anaemia using next-generation sequencing., PMID:27427187
Correlation between protein 4.1R and the progression of heart failure in vivo., PMID:27323040
[Expression of protein 4.1 family in melanoma cell lines and its effect on cell proliferation]., PMID:27222179
Identification of Target Genes Involved in Wound Healing Angiogenesis of Endothelial Cells with the Treatment of a Chinese 2-Herb Formula., PMID:26430762
Prolonged phototherapy needed for a neonate with four mutations in genes involved in bilirubin production and metabolism., PMID:25758003
[Effects of membrane skeleton protein 4.1R on the efficiency of photodynamic therapy]., PMID:25623321
The RNA binding protein RBM38 (RNPC1) regulates splicing during late erythroid differentiation., PMID:24250749
Variations in both α-spectrin (SPTA1) and β-spectrin ( SPTB ) in a neonate with prolonged jaundice in a family where nine individuals had hereditary elliptocytosis., PMID:24193021
For research use only. Not for human or drug use.
