Catalog No.
YHC85701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu47-Pro478
Predicted molecular weight
50.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11150
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Phospholipase A1, Lipase member C, LIPC, Hepatic lipase, Hepatic triacylglycerol lipase, Lysophospholipase, HTGL, HL
Activity-Based Protein Profiling to Study Virus-Host and Viral-Induced MicroRNA-Host Interactions., PMID:40515990
Reciprocal Fluctuations in Lipoprotein Lipase, Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1, and Hepatic Triglyceride Lipase Levels in the Peripheral Bloodstream Are Correlated with Insulin Resistance., PMID:40507147
A rare gain of function variant of hepatic lipase attenuates hypercholesterolemia and atherosclerosis in mice via an LDL receptor-independent mechanism., PMID:40460236
A galactolipase activated by high light helps cells acclimate to stress in cyanobacteria., PMID:40181794
Effect of limb ischemic preconditioning on the indirect index of insulin resistance in maintenance hemodialysis patients., PMID:40158091
Gene-Diet Interactions in High-Density Lipoprotein Cholesterol-Related Polymorphisms and Cardiovascular Disease Risk: Insights from the Korean Genome and Epidemiology Study., PMID:40077648
Effect of PCSK9 Inhibitors on Regulators of Lipoprotein Homeostasis, Inflammation and Coagulation., PMID:40002707
FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis., PMID:39871339
FXR activation reduces the formation of macrophage foam cells and atherosclerotic plaque, possibly by down regulating hepatic lipase in macrophages., PMID:39601316
Phenotype in Individuals with Heterozygous Rare Variants in LIPC Encoding Hepatic Lipase., PMID:39518997
Natural Honey Proteins Prevent Diet-Induced Obesity and Metabolic Disorders in Rats., PMID:39479977
Detection of structural variants linked to mutton flavor and odor in two closely related black goat breeds., PMID:39425017
Imaging macular carotenoids and their related proteins in the human retina with confocal resonance Raman and fluorescence microscopy., PMID:39151780
Association of the ESR1 (rs9340799), OLR1 (rs3736234), LIPC (rs2070895), VDR (rs2228570), and CETP (rs708272) Polymorphisms With Risk of Coronary Artery Disease in Iranian Patients., PMID:38506378
Rare and common coding variants in lipid metabolism-related genes and their association with coronary artery disease., PMID:38336686
The translational potential of miR-26 in atherosclerosis and development of agents for its target genes ACC1/2, COL1A1, CPT1A, FBP1, DGAT2, and SMAD7., PMID:38195542
Increased Expression of LIPC Is Associated With the Clinicopathological Features and Development of Head and Neck Squamous Cell Carcinoma., PMID:38192945
Identifying the natural products in the treatment of atherosclerosis by increasing HDL-C level based on bioinformatics analysis, molecular docking, and in vitro experiment., PMID:38115108
[Identification and 3D architecture analysis of the LIPC gene mutation in a pedigree with familial hypercholesterolemia-like phenotype]., PMID:37460425
Molecular Basis of Hereditary Hair Diseases., PMID:37407443
Association of LIPC polymorphisms with stroke risk in the Chinese population., PMID:37273686
APOC3 and ABCA1 variants in unusual combined hypolipidaemia showing premature peripheral vascular disease., PMID:36876364
Mechanism for the selective uptake of macular carotenoids mediated by the HDL cholesterol receptor SR-BI., PMID:36863431
Targeted sequencing of a gene panel in patients with familial hypercholesterolemia from Southern Poland., PMID:36648309
Whole-exome sequencing identifies novel protein-altering variants associated with serum apolipoprotein and lipid concentrations., PMID:36419110
Genetic Mimicry Analysis Reveals the Specific Lipases Targeted by the ANGPTL3-ANGPTL8 Complex and ANGPTL4., PMID:36372100
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis., PMID:36274132
Genetic factors help explain the variable responses of young children with cystic fibrosis to vitamin D supplements., PMID:36184229
[Association analysis of seven single nucleotide polymorphisms identified by genome-wide association study with age-related macular degeneration among ethnic Han Chinese population]., PMID:36082566
Gain-of-Function Variants in Lipid Genes Enhance Biological Insight and Point Toward Therapeutic Opportunities., PMID:36067277
Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk., PMID:36055244
Pulmonary embolism and 529 human blood metabolites: genetic correlation and two-sample Mendelian randomization study., PMID:36038828
LIPC variant in combined hypocholesterolaemia., PMID:35978009
Association of lipid metabolism-related gene promoter methylation with risk of coronary artery disease., PMID:35941416
Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia., PMID:35899625
Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease., PMID:35884923
Altered hippocampal GR/KCC2 signaling mediates susceptibility to convulsion in male offspring following dexamethasone exposure during pregnancy in rats., PMID:35595036
Effects of heat-processed Gynostemma pentaphyllum on high-fat diet-fed mice of obesity and functional analysis on network pharmacology and molecular docking strategy., PMID:35513215
microRNA-27b regulates hepatic lipase enzyme LIPC and reduces triglyceride degradation during hepatitis C virus infection., PMID:35483451
Genotyping of Clinical Parameters in Age-Related Macular Degeneration., PMID:35241908
Metformin enhances LDL-cholesterol uptake by suppressing the expression of the pro-protein convertase subtilisin/kexin type 9 (PCSK9) in liver cells., PMID:35237909
Modulated anti-VEGF therapy under the influence of lipid metabolizing proteins in Age related macular degeneration: a pilot study., PMID:35027571
A rapid increase in lysophospholipids after geranylgeranoic acid treatment in human hepatoma-derived HuH-7 cells revealed by metabolomics analysis., PMID:34869922
Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke., PMID:34668383
Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-cholesterol Levels in J-MICC Study Participants., PMID:34421081
Evolution of Subfamily I.1 Lipases in Pseudomonas aeruginosa., PMID:34279672
Genome-Wide Association Study Identifies a Functional SIDT2 Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease., PMID:34233476
Potential role of hepatic lipase in the accretion of docosahexaenoic acid (DHA) by the brain., PMID:34197964
Comparative Immunomodulatory Evaluation of the Receptor Binding Domain of the SARS-CoV-2 Spike Protein; a Potential Vaccine Candidate Which Imparts Potent Humoral and Th1 Type Immune Response in a Mouse Model., PMID:34108961
Sleeping pattern and activities of daily living modulate protein expression in AMD., PMID:34061866
For research use only. Not for human or drug use.
