Catalog No.
RHG12101
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, WB: 1:1000-1:2000
Target
PDE4B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, PDE32, DPDE4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q07343
Applications
FCM, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2D05
Genomic architecture of carcass and pork traits and their association with immune capacity., PMID:38113634
Next Generation PDE4 Inhibitors that Selectively Target PDE4B/D Subtypes: A Narrative Review., PMID:37924462
The potential value of amlexanox in the treatment of cancer: Molecular targets and therapeutic perspectives., PMID:34968491
Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways., PMID:31730855
Respiratory Drugs During Breastfeeding., PMID:31526183
Synergistic Targeting of the Regulatory and Catalytic Subunits of PI3Kδ in Mature B-cell Malignancies., PMID:29246942
Heptamethoxyflavone Reduces Phosphodiesterase Activity and T-Cell Growth in vitro., PMID:29130985
Machine learning-based classification of diffuse large B-cell lymphoma patients by eight gene expression profiles., PMID:26869285
Expression and distribution of phosphodiesterase isoenzymes in the human male urethra., PMID:25704994
Phosphodiesterase 4 inhibition in the treatment of psoriasis, psoriatic arthritis and other chronic inflammatory diseases., PMID:23888251
Expression and distribution of phosphodiesterase isoenzymes in the human seminal vesicles., PMID:21810184
Spontaneous high-titered IgG antibody responses against BCL-2 in patients with aggressive lymphomas., PMID:19234720
Survey of schizophrenia and bipolar disorder candidate genes using chromatin immunoprecipitation and tiled microarrays (ChIP-chip)., PMID:19225952
Effect of orally administered KF66490, a phosphodiesterase 4 inhibitor, on dermatitis in mouse models., PMID:18854230
Molecular discrimination of responders and nonresponders to anti-TNF alpha therapy in rheumatoid arthritis by etanercept., PMID:18454843
Splice variants of the cyclic nucleotide phosphodiesterase PDE4D are differentially expressed and regulated in rat tissue., PMID:15717866
Identification and quantification of phosphodiesterase 4 subtypes in CD4 and CD8 lymphocytes from healthy and asthmatic subjects., PMID:11429397
Surgically induced cryptorchidism-related degenerative changes in spermatogonia are associated with loss of cyclic adenosine monophosphate-dependent phosphodiesterases type 4 in abdominal testes of rats., PMID:11369582
Noradrenergic lesions differentially alter the expression of two subtypes of low Km cAMP-sensitive phosphodiesterase type 4 (PDE4A and PDE4B) in rat brain., PMID:10837797
Effects of noradrenergic lesions on the development of rolipram-sensitive, low-K(m), cyclic AMP specific phosphodiesterase in rat brain., PMID:10521562
Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect., PMID:10213096
Specific CD3 epsilon association of a phosphodiesterase 4B isoform determines its selective tyrosine phosphorylation after CD3 ligation., PMID:9973473
Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: identification and differential expression of immunologically distinct forms in the rat brain., PMID:9443929
Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B., PMID:8632354
Salbutamol up-regulates PDE4 activity and induces a heterologous desensitization of U937 cells to prostaglandin E2. Implications for the therapeutic use of beta-adrenoceptor agonists., PMID:7559525
Characterization of a hormone-inducible, high affinity adenosine 3'-5'-cyclic monophosphate phosphodiesterase from the rat Sertoli cell., PMID:7794911
For research use only. Not for human or drug use.
