Catalog No.
YHC84701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu22-Pro170
Predicted molecular weight
19.09 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10966
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD8B1, T-cell surface glycoprotein CD8 beta chain, CD8B, CD8b
NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model., PMID:39932765
The High-Affinity IL-2 Receptor Affects White Matter Damage after Cerebral Ischemia by Regulating CD8 + T Lymphocyte Differentiation., PMID:39821696
Sexual dimorphism in lung transcriptomic adaptations in fetal alcohol spectrum disorders., PMID:39780208
The Novel HDAC Inhibitor OBP-801 Promotes MHC Class I Presentation Through LMP2 Upregulation, Enhancing the PD-1-Targeting Therapy in Clear Cell Renal Cell Carcinoma., PMID:39682244
Effects of parity and early pregnancy on peripheral blood leukocytes in dairy cattle., PMID:39216517
Immunomic longitudinal profiling of the NeoPembrOv trial identifies drivers of immunoresistance in high-grade ovarian carcinoma., PMID:39013886
Biomarker discovery with quantum neural networks: a case-study in CTLA4-activation pathways., PMID:38609844
Cancer cell immunity-related protein co-expression networks are associated with early-stage solid-predominant lung adenocarcinoma., PMID:38450191
Impact of Mutations in Subunit Genes of the Mammalian SWI/SNF Complex on Immunological Tumor Microenvironment., PMID:38151294
Systemic immune response of rainbow trout exposed to Flavobacterium psychrophilum infection., PMID:38128681
Single-cell RNA sequencing reveals immune microenvironment of small cell lung cancer-associated malignant pleural effusion., PMID:38010064
YAP1/Piezo1 involve in the dynamic changes of lymphatic vessels in UVR-induced photoaging progress to squamous cell carcinoma., PMID:37974224
High CD8+tumor-infiltrating lymphocytes indicate severe exhaustion and poor prognosis in angioimmunoblastic T-cell lymphoma., PMID:37781365
Spike protein is a key target for stronger and more persistent T-cell responses-a study of mild and asymptomatic SARS-CoV-2 infection., PMID:37683720
HCST Expression Distinguishes Immune-hot and Immune-cold Subtypes in Pancreatic Ductal Adenocarcinoma., PMID:37475556
Genome-wide DNA methylation profile analysis identifies an individualized predictive signature for melanoma immune response., PMID:36595044
Tumor microenvironment gene expression profiles associated to complete pathological response and disease progression in resectable NSCLC patients treated with neoadjuvant chemoimmunotherapy., PMID:36171009
Assessment of DNA methylation in porcine immune cells reveals novel regulatory elements associated with cell-specific gene expression and immune capacity traits., PMID:35953767
Autoimmunity is a hallmark of post-COVID syndrome., PMID:35296346
Insufficiency of CD205-positive cortical thymic epithelial cells in immature Japanese Black cattle with severe thymic abnormalities and poor prognosis., PMID:35038635
Decreased expression of T-cell-associated immune markers predicts poor prognosis in patients with follicular lymphoma., PMID:34837284
Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology., PMID:34412704
Clonal Expansion of Tumor-Infiltrating T Cells and Analysis of the Tumor Microenvironment within Esophageal Squamous Cell Carcinoma Relapsed after Definitive Chemoradiation Therapy., PMID:33499345
CD4, CD8b, and Cytokines Expression Profiles in Peripheral Blood Mononuclear Cells Infected with Different Subtypes of KoRV from Koalas (Phascolarctos cinereus) in a Japanese Zoo., PMID:33316950
ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth., PMID:33148660
The function annotations of ST3GAL4 in human LAMP1 and Lassa virus GP-C interaction from the perspective of systems virology., PMID:32974605
Robust CD8+ T-cell proliferation and diversification after mogamulizumab in patients with adult T-cell leukemia-lymphoma., PMID:32433748
Single or Combined Dietary Supply of Psidium guajava and Phyllanthus amarus Extracts Differentially Modulate Immune Responses and Liver Proteome in Striped Catfish (Pangasianodon hyphophthalmus)., PMID:32431710
FAM83H overexpression predicts worse prognosis and correlates with less CD8+ T cells infiltration and Ras-PI3K-Akt-mTOR signaling pathway in pancreatic cancer., PMID:32424701
NGS Evaluation of Colorectal Cancer Reveals Interferon Gamma Dependent Expression of Immune Checkpoint Genes and Identification of Novel IFNγ Induced Genes., PMID:32265897
Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity., PMID:31940721
The TLR9 agonist (GNKG168) induces a unique immune activation pattern in vivo in children with minimal residual disease positive acute leukemia: Results of the TACL T2009-008 phase I study., PMID:31530240
Tumor growth inhibition by mSTEAP peptide nanovaccine inducing augmented CD8+ T cell immune responses., PMID:31228097
FGL2 promotes tumor progression in the CNS by suppressing CD103+ dendritic cell differentiation., PMID:30683885
Fingerprints of CD8+ T cells on human pre-plasma and memory B cells., PMID:30540814
Classification of tumor microenvironment immune types based on immune response-associated gene expression., PMID:30387832
A radiomics approach to assess tumour-infiltrating CD8 cells and response to anti-PD-1 or anti-PD-L1 immunotherapy: an imaging biomarker, retrospective multicohort study., PMID:30120041
Co-expression Analysis of Sirtuins and Related Metabolic Biomarkers in Juveniles of Gilthead Sea Bream (Sparus aurata) With Differences in Growth Performance., PMID:29922168
Contradictory intrahepatic immune responses activated in high-load hepatitis C virus livers compared with low-load livers., PMID:29248968
ADAR1 expression is associated with tumour-infiltrating lymphocytes in triple-negative breast cancer., PMID:29022489
Gene expression profiles associated with lymphocystis disease virus (LCDV) in experimentally infected Senegalese sole (Solea senegalensis)., PMID:28476672
Differential expression of major histocompatibility complex class I in subtypes of breast cancer is associated with estrogen receptor and interferon signaling., PMID:27121061
Local and systemic inflammatory and immunologic reactions to cyathostomin larvicidal therapy in horses., PMID:26429413
The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response., PMID:25451162
cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cells., PMID:24297179
cAMP-responsive element modulator α (CREMα) trans-represses the transmembrane glycoprotein CD8 and contributes to the generation of CD3+CD4-CD8- T cells in health and disease., PMID:24047902
Short-lived effector CD8 T cells induced by genetically attenuated malaria parasite vaccination express CD11c., PMID:23980113
The human CD8β M-4 isoform dominant in effector memory T cells has distinct cytoplasmic motifs that confer unique properties., PMID:23533620
Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining., PMID:21677135
Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a disorder of innate immunity and Th1 activation responsive to IL-1 blockade., PMID:21478439
For research use only. Not for human or drug use.
