Catalog No.
RHF64102
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Applications
IP, WB
Recommended Dilution
| Application |
Dilution |
| IP |
1:20, WB: 1:500-1:1000 |
Target
Disintegrin and metalloproteinase domain-containing protein 8, ADAM8, CD156a, MS2, Cell surface antigen MS2, ADAM 8
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P78325
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2B24
Note
For research use only.
Reactivity of new adhesion molecules on lymphocytes from patients with chronic graft versus host disease., PMID:12793201
Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding., PMID:17548643
Human parainfluenza virus type 2 (HPIV2) induced host ADAM8 expression in human salivary adenocarcinoma cell line (HSY) during cell fusion., PMID:19284887
ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271)., PMID:19714641
CD155 on human vascular endothelial cells attenuates the acquisition of effector functions in CD8 T cells., PMID:21330602
Adam8 limits the development of allergic airway inflammation in mice., PMID:23670189
ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis., PMID:24375628
Fibronectin fragments and the cleaving enzyme ADAM-8 in the degenerative human intervertebral disc., PMID:25010013
The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells., PMID:25825051
miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells., PMID:27039296
Inducible expression of A Disintegrin and Metalloproteinase 8 in chronic periodontitis and gingival epithelial cells., PMID:27859260
IL-5-stimulated eosinophils adherent to periostin undergo stereotypic morphological changes and ADAM8-dependent migration., PMID:28378503
Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo., PMID:28425175
ADAM8 expression in breast cancer derived brain metastases: Functional implications on MMP-9 expression and transendothelial migration in breast cancer cells., PMID:28986926
ADAM8 localizes to extravillous trophoblasts within the maternal-fetal interface and potentiates trophoblast cell line migration through a β1 integrin-mediated mechanism., PMID:30124911
ADAM 8 as a novel target for doxorubicin delivery to TNBC cells using magnetic thermosensitive liposomes., PMID:33338603
For research use only. Not for human or drug use.
