Catalog No.
RHF61303
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
DBPB, EFI-A, Y-box-binding protein 1, Enhancer factor I subunit A, Y-box transcription factor, YB1, NSEP1, YBX1, Nuclease-sensitive element-binding protein 1, CBF-A, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, YB-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P67809
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2A77
Transcriptome-wide identification of 5-methylcytosine by deaminase and reader protein-assisted sequencing., PMID:40197347
The TMBIM1-YBX1 axis orchestrates MDSC recruitment and immunosuppressive microenvironment in pancreatic cancer., PMID:40083936
Identification and classification of abundant RNA-binding proteins in the mouse lens and interactions of Carhsp1, Igf2bp1/ZBP1, and Ybx1 with crystallin and β-actin mRNAs., PMID:39829794
M6A-mediated upregulation of lncRNA TUG1 in liver cancer cells regulates the antitumor response of CD8+ T cells and phagocytosis of macrophages., PMID:38981064
CDKL1 potentiates the antitumor efficacy of radioimmunotherapy by binding to transcription factor YBX1 and blocking PD-L1 expression in lung cancer., PMID:38520004
Characterised intron retention profiles in muscle tissue of idiopathic inflammatory myopathy subtypes., PMID:38302260
Regulatory mechanism of interaction between Y-box-binding protein 1 and heterogenous nuclear ribonucleoprotein K in cell division cycle 25a signal pathway and lung cancer metastasis., PMID:38279484
Neural Stem Cell Extracellular Vesicles Carrying YBX1 Inhibited Neuronal Pyroptosis Through Increasing m6A-modified GPR30 Stability and Expression in Ischemic Stroke., PMID:37966628
Screening of Tnfaip1-Interacting Proteins in Zebrafish Embryonic cDNA Libraries Using a Yeast Two-Hybrid System., PMID:37886961
YBX1/lncRNA SBF2-AS1 interaction regulates proliferation and tamoxifen sensitivity via PI3K/AKT/MTOR signaling in breast cancer cells., PMID:36754932
Long noncoding RNA HOTAIR interacts with Y-Box Protein-1 (YBX1) to regulate cell proliferation., PMID:34266873
Using RNA-binding proteins for immunoprecipitation of mRNAs from Xenopus laevis embryos., PMID:34195668
Ybx1 fine-tunes PRC2 activities to control embryonic brain development., PMID:32792512
LINC00312/YBX1 Axis Regulates Myofibroblast Activities in Oral Submucous Fibrosis., PMID:32340273
Peptides of neuron specific enolase as potential ASD biomarkers: From discovery to epitope mapping., PMID:31812776
Nimotuzumab inhibits epithelial-mesenchymal transition in prostate cancer by targeting the Akt/YB-1/AR axis., PMID:30907986
The soluble ligand Y box-1 activates Notch3 receptor by binding to epidermal growth factor like repeats 20-23., PMID:30321499
The Oncolytic Adenovirus XVir-N-31 as a Novel Therapy in Muscle-Invasive Bladder Cancer., PMID:29916265
Heat shock protein 70 inhibitors suppress androgen receptor expression in LNCaP95 prostate cancer cells., PMID:28691182
Y-box Binding Protein 1 Is Involved in Regulating the G2/M Phase of the Cell Cycle., PMID:28373420
PAR-CLIP and streamlined small RNA cDNA library preparation protocol for the identification of RNA binding protein target sites., PMID:27871973
Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction., PMID:27559612
Uncoupling of EGFR-RAS signaling and nuclear localization of YBX1 in colorectal cancer., PMID:26779809
Critical role of phosphorylation of serine 165 of YBX1 on the activation of NF-κB in colon cancer., PMID:26318844
HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform., PMID:25354590
Search for ligand of N-acetylglucosaminyl-N-acetylmuramyl dipeptide using its peptide mimetic., PMID:24794728
YB-1 expression promotes epithelial-to-mesenchymal transition in prostate cancer that is inhibited by a small molecule fisetin., PMID:24770864
High prevalence of Y-box protein-1/p18 fragment in plasma of patients with malignancies of different origin., PMID:24443788
Links between the oncoprotein YB-1 and small non-coding RNAs in breast cancer., PMID:24260353
Autism-specific maternal autoantibodies recognize critical proteins in developing brain., PMID:23838888
Low expression of the X-linked ribosomal protein S4 in human serous epithelial ovarian cancer is associated with a poor prognosis., PMID:23800275
GW/P-bodies and autoimmune disease., PMID:23224965
Elevated nuclear YB1 expression is associated with poor survival of patients with early breast cancer., PMID:22843890
Y-box binding protein-1 implicated in translational control of fetal myocardial gene expression after cardiac transplant., PMID:22619371
MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition., PMID:22249268
A new regulatory function of the region proximal to the RGG box in the fragile X mental retardation protein., PMID:21868366
Prognostic association of YB-1 expression in breast cancers: a matter of antibody., PMID:21695211
YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention., PMID:21576761
YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification., PMID:21423216
The expression of activated Y-box binding protein-1 serine 102 mediates trastuzumab resistance in breast cancer cells by increasing CD44+ cells., PMID:20802512
Nuclear detection of Y-box protein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer., PMID:19930682
Genotoxic stress-induced nuclear localization of oncoprotein YB-1 in the absence of proteolytic processing., PMID:19838214
Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs., PMID:19029303
Probing the mRNA processing body using protein macroarrays and "autoantigenomics"., PMID:17339575
[Serological screening of autoantigens associated with vasculitis in systemic lupus erythematosus]., PMID:17294748
Fragmented hyaluronan induces transcriptional up-regulation of the multidrug resistance-1 gene in CD4+ T cells., PMID:17038319
Formation of a nuclear complex containing the p53 tumor suppressor, YB-1, and the Werner syndrome gene product in cells treated with UV light., PMID:16584908
A novel Ded1-like RNA helicase interacts with the Y-box protein ctYB-1 in nuclear mRNP particles and in polysomes., PMID:16556597
Y-box binding protein, YB-1, as a marker of tumor aggressiveness and response to adjuvant chemotherapy in breast cancer., PMID:15703814
YB-1 represses AP1-dependent gene transactivation and interacts with an AP-1 DNA sequence., PMID:15702969