Catalog No.
YHC81401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp30-Tyr224
Predicted molecular weight
23.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10586
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Leukocyte common antigen related, Receptor-type tyrosine-protein phosphatase F, PTPRF, LAR
Unraveling ADHD: genes, co-occurring traits, and developmental dynamics., PMID:40000109
KLF3 impacts insulin sensitivity and glucose uptake in skeletal muscle., PMID:39250818
Exploring the Biomarkers and Potential Mechanisms of Botulinum Toxin Type A in the Treatment of Microglial Inflammatory Activation through P2X7 Receptors based on Transcriptome Sequencing., PMID:39177140
Aptamer-Based Enforced Phosphatase-Recruiting Chimeras Inhibit Receptor Tyrosine Kinase Signal Transduction., PMID:39087949
Alfalfa xeno-miR159a regulates bovine mammary epithelial cell proliferation and milk protein synthesis by targeting PTPRF., PMID:38643232
Liprin-α1 contributes to oncogenic MAPK signaling by counteracting ERK activity., PMID:38264964
Transcriptomic analysis of glucosidase II beta subunit (GluIIß) knockout A549 cells reveals its roles in regulation of cell adhesion molecules (CAMs) and anti-tumor immunity., PMID:38245670
MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata., PMID:38139460
Ephexin3/ARHGEF5 Together with Cell Migration Signaling Partners within the Tumor Microenvironment Define Prognostic Transcriptional Signatures in Multiple Cancer Types., PMID:38003617
Transcriptomic analysis identifies four novel receptors potentially linking endometrial cancer with polycystic ovary syndrome and generates a transcriptomic atlas., PMID:37737665
Differentially Expressed Genes Induced by Erythropoietin Receptor Overexpression in Rat Mammary Adenocarcinoma RAMA 37-28 Cells., PMID:37239828
CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice., PMID:37173343
High expression of PPFIA1 in human esophageal squamous cell carcinoma correlates with tumor metastasis and poor prognosis., PMID:37158817
Generation of an Aptamer Targeting Receptor-Type Tyrosine-Protein Phosphatase F., PMID:36594741
High PPFIA1 expression promotes cancer survival by suppressing CD8+ T cells in breast cancer: drug discovery and machine learning approach., PMID:36478321
FSCN1 induced PTPRF-dependent tumor microenvironment inflammatory reprogramming promotes lung adenocarcinoma progression via regulating macrophagic glycolysis., PMID:36223033
The putative oncogenic role of WDTC1 in colorectal cancer., PMID:35238908
MRNA Profiling Involved in Triggering of STAT1 with Regulatory Involvement of IRF7, PTPRF, and miR-145p in Patients Suffering from Gall Bladder Carcinoma., PMID:35035811
Comparative proteomic analysis of nuclear and cytoplasmic compartments in human cardiac progenitor cells., PMID:34997006
miR-647 inhibits hepatocellular carcinoma cell progression by targeting protein tyrosine phosphatase receptor type F., PMID:34969357
LAR Receptor Tyrosine Phosphatase Family in Healthy and Diseased Brain., PMID:34966732
Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development., PMID:34863978
LncRNA TCONS_00004099-derived microRNA regulates oncogenesis through PTPRF in gliomas., PMID:34277823
Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR., PMID:33656439
Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer., PMID:32973331
circ_0080145 Enhances Imatinib Resistance of Chronic Myeloid Leukemia by Regulating miR-326/PPFIA1 Axis., PMID:32598170
Crystal and solution structures of fragments of the human leucocyte common antigen-related protein., PMID:32355037
Down-regulation of the insulin signaling pathway by SHC may correlate with congenital heart disease in Chinese populations., PMID:31971563
Characterization of Macrophage Galactose-type Lectin (MGL) ligands in colorectal cancer cell lines., PMID:31911241
PPARγ inhibits breast cancer progression by upregulating PTPRF expression., PMID:31799666
Exosomal Circular RNA as a Biomarker Platform for the Early Diagnosis of Immune-Mediated Demyelinating Disease., PMID:31611906
Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p., PMID:30886199
Structural basis of the target-binding mode of the G protein-coupled receptor kinase-interacting protein in the regulation of focal adhesion dynamics., PMID:30737283
PTPRF as a novel tumor suppressor through deactivation of ERK1/2 signaling in gastric adenocarcinoma., PMID:30464527
CD133-induced TM4SF5 expression promotes sphere growth via recruitment and blocking of protein tyrosine phosphatase receptor type F (PTPRF)., PMID:30217560
Identification of Core Genes and Key Pathways via Integrated Analysis of Gene Expression and DNA Methylation Profiles in Bladder Cancer., PMID:29739919
Structural Characterization of a Heparan Sulfate Pentamer Interacting with LAR-Ig1-2., PMID:29570275
Potential prognostic biomarkers identified by DNA methylation profiling analysis for patients with lung adenocarcinoma., PMID:29467875
Aberrant astrocytic expression of chondroitin sulfate proteoglycan receptors in a rat model of amyotrophic lateral sclerosis., PMID:28752900
In utero exposure to diesel exhaust particulates is associated with an altered cardiac transcriptional response to transverse aortic constriction and altered DNA methylation., PMID:28751527
NGL-3-induced presynaptic differentiation of hippocampal neurons in an afadin-dependent, nectin-1-independent manner., PMID:28695613
Comparison of protein expression during wild-type, and E1B-55k-deletion, adenovirus infection using quantitative time-course proteomics., PMID:28631589
Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators., PMID:27880917
PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis., PMID:27876801
LAR protein tyrosine phosphatase regulates focal adhesions through CDK1., PMID:27352860
Regulation of Platelet Derived Growth Factor Signaling by Leukocyte Common Antigen-related (LAR) Protein Tyrosine Phosphatase: A Quantitative Phosphoproteomics Study., PMID:27074791
Unbiased identification of substrates of protein tyrosine phosphatase ptp-3 in C. elegans., PMID:27067626
Quantitative proteomics reveals protein kinases and phosphatases in the individual phases of contextual fear conditioning in the C57BL/6J mouse., PMID:26748257
Evaluation of drug-targetable genes by defining modes of abnormality in gene expression., PMID:26336805
PTPRF Expression as a Potential Prognostic/Predictive Marker for Treatment with Erlotinib in Non-Small-Cell Lung Cancer., PMID:26291013
For research use only. Not for human or drug use.
