Catalog No.
YHC45302
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn680-Arg756
Predicted molecular weight
11.07 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P0C0L4
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C4a anaphylatoxin, CO4, CPAMD2, Acidic complement C4, C4A, Complement C4-A, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2
Note
For research use only.
Low C4A copy numbers and higher HERV gene insertion contributes to increased risk of SLE, with absence of association with disease phenotype and disease activity., PMID:38594415
Proteomics in Patients with Fibromyalgia Syndrome: A Systematic Review of Observational Studies., PMID:38652420
Electrophoresis-Based Approach for Characterizing Dendrimer-Protein Interactions: A Proof-of-Concept Study., PMID:38753577
Comparison of CTX-M encoding plasmids present during the early phase of the ESBL pandemic in western Sweden., PMID:38789462
Genetic associations in ankylosing spondylitis: circulating proteins as drug targets and biomarkers., PMID:38835753
Serum proteomic analysis uncovers novel serum biomarkers for depression., PMID:38895030
Identification of novel therapeutic targets for chronic kidney disease and kidney function by integrating multi-omics proteome with transcriptome., PMID:38898508
Complement system molecules: Expression and regulation at the maternal-conceptus interface during pregnancy in pigs., PMID:39004297
A multi-ethnic proteomic profiling analysis in Alzheimer's disease identifies the disparities in dysregulation of proteins and pathogenesis., PMID:39035156
Analysis of the complement component C4 gene with schizophrenia subphenotypes., PMID:39084106
Decoding the genetic landscape of juvenile dermatomyositis: insights from phosphorylation-associated single nucleotide polymorphisms., PMID:39085621
Sequential window acquisition of all theoretical mass spectra (SWATH-MS) as an emerging proteomics approach for the discovery of dark-cutting beef biomarkers., PMID:39096797
Kidney whole-transcriptome profiling in primary antiphospholipid syndrome reveals complement, interferons and NETs-related gene expression., PMID:39107892
Causal relationship between complement C1QB and colorectal cancer: a drug target Mendelian randomization study., PMID:39109334
Different Complement Activation Patterns Following C5 Cleavage in MOGAD and AQP4-IgG+NMOSD., PMID:39133885
Proteomic analysis of laser captured tubular tissues reveals complement activation and mitochondrial dysfunction in autoimmune related kidney diseases., PMID:39164435
Unveiling potential drug targets for lung squamous cell carcinoma through the integration of druggable genome and genome-wide association data., PMID:39175755
Different Proteomic Profiles Regarding Antihypertensive Therapy in Preeclampsia Pregnant., PMID:39201423
Lipidomic and Proteomic Insights from Extracellular Vesicles in Postmortem Dorsolateral Prefrontal Cortex Reveal Substance Use Disorder-Induced Brain Changes., PMID:39211229
The structure of Chlamydomonas LOV1 as revealed by time-resolved serial synchrotron crystallography., PMID:39212519
Impact of Preanalytical Procedures on Complement Biomarkers in Cerebrospinal Fluid and Plasma from Controls and Alzheimer's Disease Patients., PMID:39213066
Effect of Kruppel-like factor 4 on PTZ-induced acute seizure mice., PMID:39234952
Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes., PMID:39251599
Proteomic analysis of cerebrospinal fluid of amyotrophic lateral sclerosis patients in the presence of autologous bone marrow derived mesenchymal stem cells., PMID:39278909
Sex-dependent association study of complement C4 gene with treatment-resistant schizophrenia and hospitalization frequency., PMID:39342786
CSF complement proteins are elevated in prodromal to moderate Alzheimer's disease patients and are not altered by the anti-tau antibody semorinemab., PMID:39369294
Mechanistic Perspective on Oxygen Activation Chemistry by Flavoenzymes., PMID:39424594
High-abundance serum glycoproteins as valuable resources for glycopeptide standards., PMID:39486975
Regioselective Synthesis of Potential Non-Quinonoid Prodrugs of Plasmodione: Antiparasitic Properties Against Two Hemoglobin-Feeding Parasites and Drug Metabolism Studies., PMID:39598657
Africanized honeybee venom (Apis mellifera) promotes human complement activation split products storm., PMID:39606222
Complement Activation Profiles Predict Clinical Outcomes in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease., PMID:39661937
Proteomic signatures of Alzheimer's disease and Lewy body dementias: A comparative analysis., PMID:39711511
Comparative proteomic analysis reveals the response mechanism of freshwater leech (Whitmania pigra) under heat-stress challenge., PMID:39729945
Aberrant Complement Activation Is Associated With Structural Brain Damage in Multiple Sclerosis., PMID:39752618
Avian pathogenic Escherichia coli alters complement gene expression in chicken erythrocytes., PMID:39757946
Unlocking the catalytic precision of ligand-controlled enzymatic halogenation., PMID:39793036
Association of C4 Null Alleles and Persistently Low C4 in Asian Indian Patients With Systemic Lupus Erythematosus., PMID:39800843
N-terminomics profiling of host proteins targeted by excretory-secretory proteases of the nematode Angiostrongylus vasorum identifies points of interaction with canine coagulation and complement cascade., PMID:39813225
Mechanisms and applications of bacterial luciferase and its auxiliary enzymes., PMID:39824239
Use of brain MRI and gene expression atlases to reconstruct the pathophysiology of autoimmune neurological disorders: The proof-of-concept of NMOSD., PMID:39891565
Plasma proteome fingerprint in kidney diseases., PMID:39896931
Integrative Multi-omics Analysis and Mendelian Randomization Reveal Potential Therapeutic Targets and their Stratification in Lung Squamous Cell Carcinoma., PMID:39936431
HTRA1 and complement activation in neovascular age-related macular degeneration., PMID:39937341
Genome-wide mapping of complement system proteins for islet autoimmunity in the DAISY and TEDDY children., PMID:39989961
Assessment of complement cascade components in patients with major depressive disorder., PMID:40064429
Genetically druggable targets for MAPK-activated colorectal cancer by a two-sample mendelian randomization analysis., PMID:40210889
Proteomic and In Silico Analyses Highlight Complement System's Role in Bladder Cancer Immune Regulation., PMID:40283026
Proteomic Insights into IgA Nephropathy: A Comprehensive Analysis of Differentially Expressed Proteins in the Kidney., PMID:40352523
Complement component C4a binds to oxytocin and modulates plasma oxytocin concentrations and social behavior in male mice., PMID:40393160
Comprehensive Mendelian randomization analysis and experimental investigation identifies the causal relationship between immunity and kidney stone disease., PMID:40498118
For research use only. Not for human or drug use.
