Catalog No.
YHC45301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr1021-Thr1330
Predicted molecular weight
35.69 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P0C0L4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CO4, CPAMD2, Acidic complement C4, C4A, Complement C4-A, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2
Comprehensive Mendelian randomization analysis and experimental investigation identifies the causal relationship between immunity and kidney stone disease., PMID:40498118
Complement component C4a binds to oxytocin and modulates plasma oxytocin concentrations and social behavior in male mice., PMID:40393160
Proteomic Insights into IgA Nephropathy: A Comprehensive Analysis of Differentially Expressed Proteins in the Kidney., PMID:40352523
Proteomic and In Silico Analyses Highlight Complement System's Role in Bladder Cancer Immune Regulation., PMID:40283026
Genetically druggable targets for MAPK-activated colorectal cancer by a two-sample mendelian randomization analysis., PMID:40210889
Assessment of complement cascade components in patients with major depressive disorder., PMID:40064429
Genome-wide mapping of complement system proteins for islet autoimmunity in the DAISY and TEDDY children., PMID:39989961
HTRA1 and complement activation in neovascular age-related macular degeneration., PMID:39937341
Integrative Multi-omics Analysis and Mendelian Randomization Reveal Potential Therapeutic Targets and their Stratification in Lung Squamous Cell Carcinoma., PMID:39936431
Plasma proteome fingerprint in kidney diseases., PMID:39896931
Use of brain MRI and gene expression atlases to reconstruct the pathophysiology of autoimmune neurological disorders: The proof-of-concept of NMOSD., PMID:39891565
Mechanisms and applications of bacterial luciferase and its auxiliary enzymes., PMID:39824239
N-terminomics profiling of host proteins targeted by excretory-secretory proteases of the nematode Angiostrongylus vasorum identifies points of interaction with canine coagulation and complement cascade., PMID:39813225
Association of C4 Null Alleles and Persistently Low C4 in Asian Indian Patients With Systemic Lupus Erythematosus., PMID:39800843
Unlocking the catalytic precision of ligand-controlled enzymatic halogenation., PMID:39793036
Avian pathogenic Escherichia coli alters complement gene expression in chicken erythrocytes., PMID:39757946
Aberrant Complement Activation Is Associated With Structural Brain Damage in Multiple Sclerosis., PMID:39752618
Comparative proteomic analysis reveals the response mechanism of freshwater leech (Whitmania pigra) under heat-stress challenge., PMID:39729945
Proteomic signatures of Alzheimer's disease and Lewy body dementias: A comparative analysis., PMID:39711511
Complement Activation Profiles Predict Clinical Outcomes in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease., PMID:39661937
Africanized honeybee venom (Apis mellifera) promotes human complement activation split products storm., PMID:39606222
Regioselective Synthesis of Potential Non-Quinonoid Prodrugs of Plasmodione: Antiparasitic Properties Against Two Hemoglobin-Feeding Parasites and Drug Metabolism Studies., PMID:39598657
High-abundance serum glycoproteins as valuable resources for glycopeptide standards., PMID:39486975
Mechanistic Perspective on Oxygen Activation Chemistry by Flavoenzymes., PMID:39424594
CSF complement proteins are elevated in prodromal to moderate Alzheimer's disease patients and are not altered by the anti-tau antibody semorinemab., PMID:39369294
Sex-dependent association study of complement C4 gene with treatment-resistant schizophrenia and hospitalization frequency., PMID:39342786
Proteomic analysis of cerebrospinal fluid of amyotrophic lateral sclerosis patients in the presence of autologous bone marrow derived mesenchymal stem cells., PMID:39278909
Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes., PMID:39251599
Effect of Kruppel-like factor 4 on PTZ-induced acute seizure mice., PMID:39234952
Impact of Preanalytical Procedures on Complement Biomarkers in Cerebrospinal Fluid and Plasma from Controls and Alzheimer's Disease Patients., PMID:39213066
The structure of Chlamydomonas LOV1 as revealed by time-resolved serial synchrotron crystallography., PMID:39212519
Lipidomic and Proteomic Insights from Extracellular Vesicles in Postmortem Dorsolateral Prefrontal Cortex Reveal Substance Use Disorder-Induced Brain Changes., PMID:39211229
Different Proteomic Profiles Regarding Antihypertensive Therapy in Preeclampsia Pregnant., PMID:39201423
Unveiling potential drug targets for lung squamous cell carcinoma through the integration of druggable genome and genome-wide association data., PMID:39175755
Proteomic analysis of laser captured tubular tissues reveals complement activation and mitochondrial dysfunction in autoimmune related kidney diseases., PMID:39164435
Different Complement Activation Patterns Following C5 Cleavage in MOGAD and AQP4-IgG+NMOSD., PMID:39133885
Causal relationship between complement C1QB and colorectal cancer: a drug target Mendelian randomization study., PMID:39109334
Kidney whole-transcriptome profiling in primary antiphospholipid syndrome reveals complement, interferons and NETs-related gene expression., PMID:39107892
Sequential window acquisition of all theoretical mass spectra (SWATH-MS) as an emerging proteomics approach for the discovery of dark-cutting beef biomarkers., PMID:39096797
Decoding the genetic landscape of juvenile dermatomyositis: insights from phosphorylation-associated single nucleotide polymorphisms., PMID:39085621
Analysis of the complement component C4 gene with schizophrenia subphenotypes., PMID:39084106
A multi-ethnic proteomic profiling analysis in Alzheimer's disease identifies the disparities in dysregulation of proteins and pathogenesis., PMID:39035156
Complement system molecules: Expression and regulation at the maternal-conceptus interface during pregnancy in pigs., PMID:39004297
Identification of novel therapeutic targets for chronic kidney disease and kidney function by integrating multi-omics proteome with transcriptome., PMID:38898508
Serum proteomic analysis uncovers novel serum biomarkers for depression., PMID:38895030
Genetic associations in ankylosing spondylitis: circulating proteins as drug targets and biomarkers., PMID:38835753
Comparison of CTX-M encoding plasmids present during the early phase of the ESBL pandemic in western Sweden., PMID:38789462
Electrophoresis-Based Approach for Characterizing Dendrimer-Protein Interactions: A Proof-of-Concept Study., PMID:38753577
Proteomics in Patients with Fibromyalgia Syndrome: A Systematic Review of Observational Studies., PMID:38652420
Low C4A copy numbers and higher HERV gene insertion contributes to increased risk of SLE, with absence of association with disease phenotype and disease activity., PMID:38594415
For research use only. Not for human or drug use.
