Catalog No.
RHE40604
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
GRK6, GPRK6, G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P43250
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1W46
[Screening and validation of therapeutic targets for chronic sinusitis with nasal polyps based on proteomics]., PMID:39107122
Suitability of GRK Antibodies for Individual Detection and Quantification of GRK Isoforms in Western Blots., PMID:35163118
Inhibition of G Protein-Coupled Receptor Kinase 2 Promotes Unbiased Downregulation of IGF1 Receptor and Restrains Malignant Cell Growth., PMID:33158816
A novel monoclonal antibody against human GRK6 antigen., PMID:25723280
Decreased expression and role of GRK6 in spinal cord of rats after chronic constriction injury., PMID:23979726
Tissue dependent differences in G-protein coupled receptor kinases associated with 5-HT4 receptor desensitization in the rat gastro-intestinal tract., PMID:20836992
Lysophosphatidylcholines activate G2A inducing G(αi)₋₁-/G(αq/)₁₁- Ca²(+) flux, G(βγ)-Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs., PMID:20799926
Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling., PMID:20048153
Phosphorylation of the beta2-adrenergic receptor in plasma membranes by intrinsic GRK5., PMID:18034461
Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2., PMID:17207480
Myocardial expression and redistribution of GRKs in hypertensive hypertrophy and failure., PMID:15584034
Endogenous G protein-coupled receptor kinase 6 triggers homologous beta-adrenergic receptor desensitization in primary uterine smooth muscle cells., PMID:12810562
G protein-coupled receptor kinases, beta-arrestin-2 and associated regulatory proteins in the human brain: postmortem changes, effect of age and subcellular distribution., PMID:12007830
Ligand-induced phosphorylation of anaphylatoxin receptors C3aR and C5aR is mediated by "G protein-coupled receptor kinases., PMID:10508278
Differentially regulated expression of the G-protein-coupled receptor kinases, betaARK and GRK6, during myelomonocytic cell development in vitro., PMID:8977246
Identification by polymerase chain reaction of the G protein-coupled receptor kinases expressed in the mouse gonadotropic alpha T3-1 cell line., PMID:8756570
Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases., PMID:8755530
For research use only. Not for human or drug use.
