Catalog No.
YHC42601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Phe372
Predicted molecular weight
40.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09651
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HNRNPA1, Single-strand RNA-binding protein, Heterogeneous nuclear ribonucleoprotein A1, hnRNP A1, hnRNP core protein A1, Helix-destabilizing protein, HNRPA1
Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation., PMID:40441157
Analysing Differential Alternative Splicing Events and Their Impact on Retinoblastoma Progression Using RNA-seq Metadata., PMID:40439392
Regulatory interplay of LINC00115/hnRNPA1/miR-146a-5p axis modulating EGFR signaling in LUAD progression., PMID:40403792
KHSRP promotes the malignant behavior and cisplatin resistance of bladder cancer cells through the CLASP2/MAPRE1 axis., PMID:40382315
The differential impact of HNRNPA1 isoforms on gene expression and their relevance to dsRNA-mediated innate immune response., PMID:40312500
The ribonucleoprotein hnRNPA1 mediates binding to RNA and DNA telomeric G-quadruplexes through an RGG-rich region., PMID:40209951
Triclosan exposure induces liver fibrosis in mice: The heterogeneous nuclear ribonucleoprotein A1/pyruvate kinase M2 axis drives hepatic stellate cell activation., PMID:40157328
Proteomic analysis identifies intracellular targets for avian coronavirus NSP10., PMID:40080214
LTA4H improves the tumor microenvironment and prevents HCC progression via targeting the HNRNPA1/LTBP1/TGF-β axis., PMID:40056904
Myopathic aggregation-prone variants in the TDP-43 prion-like domain: genetics paving the way., PMID:40036368
Lamb Performance and Meat Quality: The Impact of Chromium in High-Concentrate Diets and Its Molecular Effects on Skeletal Muscle During Finishing Phase., PMID:40011411
Enhanced identification of small molecules binding to hnRNPA1 via cryptic pockets mapping coupled with X-ray fragment screening., PMID:39984046
Decoding phase separation of prion-like domains through data-driven scaling laws., PMID:39937084
Serum/glucose starvation enhances binding of miR-4745-5p and miR-6798-5p to HNRNPA1 mRNA 3'UTR: A novel method to identify miRNAs binding to mRNA 3'UTR using λN peptide-boxB sequence., PMID:39896348
Mutations in hnRNP A1 drive neurodegeneration and alternative RNA splicing of neuronal gene targets., PMID:39874994
Exosomal miR-224-3p promotes lymphangiogenesis and lymph node metastasis by targeting GSK3B in gastric cancer., PMID:39866224
Impacts of hnRNP A1 Splicing Inhibition on the Brain Remyelination Proteome., PMID:39840781
Downregulation of hnRNPA1 inhibits hepatocellular carcinoma cell progression by modulating alternative splicing of ZNF207 exon 9., PMID:39834948
Benchmarking residue-resolution protein coarse-grained models for simulations of biomolecular condensates., PMID:39804953
Enhanced identification of small molecules binding to hnRNPA1 via cryptic pockets mapping coupled with X-Ray fragment screening., PMID:39763864
Abnormal ac4C modification in metabolic dysfunction associated steatotic liver cells., PMID:39762452
Regulation of physiological and pathological condensates by molecular chaperones., PMID:39756021
Comparative proteomic analysis reveals the response mechanism of freshwater leech (Whitmania pigra) under heat-stress challenge., PMID:39729945
Regulation of AUF1 alternative splicing by hnRNPA1 and SRSF2 modulate the sensitivity of ovarian cancer cells to cisplatin., PMID:39652302
Energy Stress-Induced circEPB41(2) Promotes Lipogenesis in Hepatocellular Carcinoma., PMID:39636740
C9orf72-linked arginine-rich dipeptide repeats aggravate pathological phase separation of G3BP1., PMID:39621905
Pioneering molecular screening for cervical precursor lesions and cervical cancer in sera., PMID:39610929
Higher isoform of hnRNPA1 confer Temozolomide resistance in U87MG & LN229 glioma cells., PMID:39585598
RNA-Binding Protein Hnrnpa1 Triggers Daughter Cardiomyocyte Formation by Promoting Cardiomyocyte Dedifferentiation and Cell Cycle Activity in a Post-Transcriptional Manner., PMID:39559922
Optical characterization of molecular interaction strength in protein condensates., PMID:39535884
Direct and indirect salt effects on homotypic phase separation., PMID:39531035
Dysfunctional RNA binding protein induced neurodegeneration is attenuated by inhibition of the integrated stress response., PMID:39521193
[HNRNPA1 gene is highly expressed in colorectal cancer: its prognostic implications and potential as a therapeutic target]., PMID:39505336
PTBP1 crotonylation promotes colorectal cancer progression through alternative splicing-mediated upregulation of the PKM2 gene., PMID:39497094
Hypoxia induced cellular and exosomal RPPH1 promotes breast cancer angiogenesis and metastasis through stabilizing the IGF2BP2/FGFR2 axis., PMID:39496940
Optical characterization of molecular interaction strength in protein condensates., PMID:39484615
Has_circ_0002360 facilitates immune evasion by enhancing heterogeneous nuclear ribonucleoprotein A1 stability, thereby promoting malignant progression in non-small cell lung cancer., PMID:39476941
RNA Binding Protein Dysfunction Links Smoldering/Slowly Expanding Lesions to Neurodegeneration in Multiple Sclerosis., PMID:39422285
Role of Circular RNA MMP9 in Glioblastoma Progression: From Interaction With hnRNPC and hnRNPA1 to Affecting the Expression of BIRC5 by Sequestering miR-149., PMID:39401767
Altered mRNA transport and local translation in iNeurons with RNA binding protein knockdown., PMID:39386562
Alternative splicing dynamically regulates common carp embryogenesis under thermal stress., PMID:39358679
Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity., PMID:39341825
Cross-Effects in Folding and Phase Transitions of hnRNP A1 and C9Orf72 RNA G4 In Vitro., PMID:39339364
Human hnRNPA1 reorganizes telomere-bound replication protein A., PMID:39329264
Decellularized adipose-derived matrix from Superficial layers of abdominal adipose tissue exhibits superior capacity of adipogenesis compared to deep layers., PMID:39318374
Phase separation of hnRNPA1 and TERRA regulates telomeric stability., PMID:39313323
hnRNPA1 promotes the metastasis and proliferation of gastric cancer cells through WISP2-guided Wnt/β-catenin signaling pathway., PMID:39298013
On the interface of aging, cancer, and neurodegeneration with SIRT6 and L1 retrotransposon protein interaction network., PMID:39251041
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression., PMID:39247822
CircSMAD3 represses VSMC phenotype switching and neointima formation via promoting hnRNPA1 ubiquitination degradation., PMID:39219022
For research use only. Not for human or drug use.
