Catalog No.
YHC42101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu33-Ser496
Predicted molecular weight
52.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09603
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CSF1, Macrophage colony-stimulating factor 1, CSF-1, Lanimostim, M-CSF, MCSF
Circulating protein biomarkers and their association with vulnerable plaque characteristics - a PROSPECT II substudy., PMID:40503438
Mast cells modulate macrophage biology through release of pre-stored CSF1., PMID:40480612
Plasma Proteomics-Based Identification of Novel Predictive and Diagnostic Inflammatory Biomarkers for Diabetic Foot., PMID:40474698
Intercellular communication between FAP+ fibroblasts and SPP1+ macrophages in prostate cancer via multi-omics., PMID:40438108
Harnessing local and system immune profiling delineating differential responders to first-line sintilimab (anti-PD-1 antibody) combined with chemotherapy in extensive-stage small cell lung cancer: an exploratory biomarker analysis of a phase II study., PMID:40404633
Modeling hereditary diffuse leukoencephalopathy with axonal spheroids using microglia-sufficient brain organoids., PMID:40397490
Elevated levels of salivary interleukin-34 in patients suffering from Alzheimer's disease., PMID:40389754
CSF1R ligands promote microglial proliferation but are not the sole regulators of developmental microglial proliferation., PMID:40387575
Causal Associations of Cardiovascular Proteins and Diabetic Nephropathy Revealed by Mediation and Phenome-Wide Mendelian Randomization., PMID:40383956
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Axatilimab in Healthy Japanese Male Participants: Results from a Phase 1, Randomized, Double-Blind, Dose-Escalation Study., PMID:40381116
External validation of plasma CSF1 as a preoperative prognostic marker in patients with resectable intrahepatic cholangiocarcinoma., PMID:40347719
scRNA-seq and scATAC-seq analyses highlight the role of TNF signaling pathway in chronic obstructive pulmonary disease model mice., PMID:40343927
Evaluating Axatilimab as a treatment option for chronic graft-versus-host disease., PMID:40338737
Interleukin-34-dependent perivascular macrophages promote vascular function in the brain., PMID:40315842
miR-484 in Hippocampal Astrocytes of Aged and Young Rats Targets CSF-1 to Regulate Neural Progenitor/Stem Cell Proliferation and Differentiation Into Neurons., PMID:40304412
Comprehensive profiling of candidate biomarkers and immune infiltration landscape in metabolic dysfunction-associated steatohepatitis., PMID:40292075
Fusion of glioma-associated mesenchymal stem/stromal cells with glioma cells promotes macrophage recruitment and M2 polarization via m6A modification of CSF1., PMID:40287444
Therapy-induced senescent glioblastoma cells sustain a procancer immune microenvironment by activating DDX58-mediated STAT1 signaling., PMID:40259469
Integrating network pharmacology and in vivo pharmacological validation to explore the gastroprotective mechanism of Sotetsuflavone against indomethacin-induced gastric ulcer in rats: Involvement of JAK2/STAT3 pathway., PMID:40258498
Fibroblast to macrophage-like cell transition in renal inflammatory injury through the MR/CSF1 pathway induced by aldosterone., PMID:40216224
Serum and synovial fluid levels of CSF-1 and in knee osteoarthritis and its clinical significance., PMID:40211184
Mendelian Randomization Analysis Supports a Causal Relationship Between Circulating Inflammatory Proteins and Basal Cell Carcinoma., PMID:40190471
CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion., PMID:40176374
Resident Macrophages in the Cervical Sympathetic Ganglia Participate in P2Y12 Receptor Mediated Diabetic Cardiac Autonomic Neuropathy., PMID:40146499
Follicle-Stimulating Hormone and Testosterone Play a Role in the Regulation of Sertoli Cell Functions Following Germ Cell Depletion In Vitro., PMID:40141344
The role of osteopontin in modulating macrophage phagocytosis of calcium oxalate crystals., PMID:40131428
New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma., PMID:40101804
CSF1R inhibition agents protect against cisplatin ototoxicity and synergize with immunotherapy for Head and Neck Squamous Cell Carcinoma., PMID:40073814
Expansion and pathogenic activation of skeletal muscle-resident macrophages in mdx5cv/Ccr2-/- mice., PMID:40067893
Intravitreal delivery of NMO-IgG causes primary retinal damage in the absence of optic nerve injury., PMID:40055743
LILRB4 specific overexpression in myeloid cells promotes tumor progression and immunosuppression in mouse models., PMID:40048761
Whole-exome sequencing identifies EP300 variants associated with visceral leishmaniasis relapse., PMID:40020829
Therapeutic advances in Tenosynovial giant cell Tumor: Targeting the CSF1/CSF1R axis., PMID:40020639
An evaluation of vimseltinib for treatment of tenosynovial giant cell tumors., PMID:40014878
Immunological biomarkers of response and resistance to treatment with cabozantinib and nivolumab in recurrent endometrial cancer., PMID:40010771
Disruption of GPSM1/CSF1 signaling reprograms tumor-associated macrophages to overcome anti-PD-1 resistance in colorectal cancer., PMID:40010765
Neutrophil extracellular traps impede cancer metastatic seeding via protease-activated receptor 2-mediated downregulation of phagocytic checkpoint CD24., PMID:40010762
Insights into CSF-1/CSF-1R signaling: the role of macrophage in radiotherapy., PMID:40007537
Gene Expression Signatures of Porcine Bone Marrow-Derived Antigen-Presenting Cells Infected with Classical Swine Fever Virus., PMID:40006915
Palmitic Acid Accumulation Activates Fibroblasts and Promotes Matrix Stiffness in Colorectal Cancer., PMID:39992719
Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease., PMID:39977705
[Methylation of Selected CpG-Sites of the Gene CSF1 as a Factor in Regulation of Its Expression and a Marker of Human Biological Aging]., PMID:39970113
Role of IL-34 in Tumors and Its Application to Regulate Inflammation., PMID:39951014
Identification of TNFAIP2 as a unique cellular regulator of CSF-1 receptor activation., PMID:39939179
Proliferation of renal macrophage via MR/CSF1 pathway induced with aldosterone and inhibited by esaxerenone., PMID:39923576
Development of antigen-capture enzyme-linked immunoassay for Chicken Interleukin-34., PMID:39900196
Molecular Profiling of Odontoclasts during Physiological Tooth Replacement., PMID:39876039
Genetically engineered bacteria expressing IL-34 alleviate DSS-induced experimental colitis by promoting tight junction protein expression in intestinal mucosal epithelial cells., PMID:39864284
Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestine., PMID:39853303
Proteomic Profiling of the Large-Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling., PMID:39817309
For research use only. Not for human or drug use.
