Catalog No.
YHC42001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu61-Ile172
Predicted molecular weight
15.21 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09601
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HMOX1, HO-1, HO, HO1, Heme oxygenase 1
bTRM Control of Murine Cytomegalovirus CNS Reactivation., PMID:40508083
Bioinformatics analysis of hub genes and oxidative stress-related pathways in odontogenic keratocysts., PMID:40505773
A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study., PMID:40502600
Mechanism study of naringenin in treating sepsis-induced kidney injury based on network pharmacology., PMID:40501235
Impact of SPP1 and HMOX1 Genes in Glioma: Correlations With Oncolytic Virus Infection, Adverse Prognosis and Increased Cell Proliferation., PMID:40495644
Rescuing vascular dysfunction in dorsal pancreatic arteries prevents tacrolimus-induced glucose metabolism disorder in mice., PMID:40495121
Investigating the histomorphometric changes of rabbit cornea after infection with Pseudomonas Aeruginosa and treatment with cold plasma., PMID:40494206
Rab7 inhibitor enhances stem cell differentiation into keratinocyte-like cells with anti-inflammatory properties., PMID:40491919
PTBP1 acts as a tumor suppressor in glioma by promoting HMOX1-dependent ferroptosis., PMID:40484043
Empagliflozin ameliorates RSL3-induced ferroptosis in vascular endothelial cells via the NRF2/HO-1 pathway., PMID:40483457
Hsp90 C-terminal domain inhibition enhances ferroptosis by disrupting GPX4-VDAC1 interaction to increase HMOX1 release from oligomerized VDAC1 channels., PMID:40472773
Study on the Effect of Naringenin on LPS-Induced Acute Lung Injury Based on NRF2/HO-1 Pathway., PMID:40465481
[FGF19 alleviates inflammatory injury in vascular endothelial cells by activating the Nrf2/HO-1 signaling pathway]., PMID:40462435
[Fucoidan sulfate regulates Hmox1-mediated ferroptosis to ameliorate myocardial injury in diabetic cardiomyopathy]., PMID:40461202
Alpinetin protects against iron overload related osteoarthritis via NRF2/HO-1 pathway., PMID:40455747
Perinatal nicotine-induced neurotoxicity and behavioral alterations in newborn mice are associated with oxidative stress, inflammation and downregulated Nrf2/HO-1 signaling: protective role of Anethum graveolens., PMID:40455124
Prescription FINO2 and Pirfenidone Supported in Reducing Fibrosis in Mouse Breast Tumor Tissue by Targeting SLC7A11 and HMOX1., PMID:40454509
A Novel Flavonoid Derivative of Icariside II (YS-10) Improves Erectile Dysfunction in a Diabetic Rat Model by Inhibiting Ferroptosis via Activation of the Nrf2/HO-1/GPX4 Pathway., PMID:40453214
Ameliorative Effects of the Neng-Jing-Huo Essential Oil Blend on H2O2-induced Oxidative Stress Injury in NRK-52E Cells via the AMPK/Nrf2/HO-1 Signaling Pathway., PMID:40451821
Anti-inflammatory Function of Ozonated Ethyl Ester of Unsaturated Fatty Acids., PMID:40451818
Effects of extreme heat exposure on heatstroke and liver injury in mice: The role of PPARα., PMID:40445822
The role of HMOX1-mediated ferroptosis in blue light-induced damage to retinal pigment epithelium., PMID:40442370
Marsdenia tenacissima extract accelerates ferroptosis of osteosarcoma cells by upregulating HO-1 and activating mitophagy., PMID:40441459
RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity., PMID:40437698
In Silico Analysis of Novel circRNA-miRNA-mRNA Axis in BRAFV600E Melanoma: Implications for Primary to Metastasis Transformation and TIME Modulation., PMID:40436810
Lacticaseibacillus paracasei NCU-21 improves ethanol-induced gastric mucosal injury by regulating the Nrf2/HO-1 signalling pathway and gastrointestinal microbiota in mice., PMID:40436552
Protective Effects of Panax notoginseng Saponins on Cerebral Ischemia/Reperfusion Injury: Insights Into SIRT1/NRF2/HO-1 Pathway Activation., PMID:40432445
Deciphering the Role of Ferroptosis in the Pathogenesis of Peripheral Artery Disease Myopathy., PMID:40427725
Regio- and Stereoselective Synthesis of Nitro-fatty Acids as NRF2 Pathway Activators Working under Ambient or Hypoxic Conditions., PMID:40419458
Vitamin E Inhibits Oxidative Stress and Inflammation in Stress-Induced Gastritis via Modulating Nrf2 and NF-κB Signalling Pathways., PMID:40418631
[Electroacupuncture pretreatment alleviates cerebral ischemia-reperfusion injury in rats by inhibiting ferroptosis through the gut-brain axis and the Nrf2/HO-1 signaling pathway]., PMID:40415422
[Role of the Nrf2/HO-1 pathway in cypermethrin-induced oxidative injury of mice hippocampal neurons]., PMID:40415420
Melatonin inhibits salivary gland epithelial cell ferroptosis via the NRF2/HO-1/GPX4 signaling pathway in primary Sjögren's syndrome., PMID:40413364
Sulforaphane regulates hepatic autophagy and apoptosis by modulating Kupffer cells' polarization via Nrf2/HO-1 pathway in the murine hemorrhagic shock/resuscitation model., PMID:40407885
Environmentally Relevant Lead Exposure Impacts Gene Expression in SH-SY5Y Cells Throughout Neuronal Differentiation., PMID:40397994
Ginseng peptide extract alleviates nicotine-induced oxidative stress and apoptosis in human aortic endothelial cells by preserving the balance of the Keap1/Nrf2/HO-1 signaling pathway., PMID:40394800
Colo-Protective Effects of Pentoxifylline Alone or in Combination With Mesalamine in Colitis Through Sphingosine Kinase 1/Sphingosine 1 Phosphate, and Zonula Occuldin 1 Pathways: New Molecular Approach., PMID:40387460
Solasodine suppresses nasopharyngeal carcinoma progression by inducing ferroptosis., PMID:40383858
Ameliorative effect of GLP1 agonist on vascular calcification in normoglycemic aged rat aorta via miR34a/SIRT6/NRF2/HO-1 signalling pathway., PMID:40383222
KLF15 prevents ferroptosis in vascular smooth muscle cells via interacting with p53., PMID:40382847
Cyclophosphamide-induced pulmonary toxicity involves oxidative stress, inflammation, apoptosis, and fibrosis with impaired Nrf2/HO-1 Signaling: Protective role of rosmarinic acid., PMID:40379079
Far-Infrared Radiation Ameliorates the Cognitive Dysfunction in an Alzheimer's Disease Transgenic Mouse via Modulating Jak-2/Stat3 and Nrf-2/HO-1 Pathways., PMID:40374872
Anti-Inflammatory Mechanisms of Pleurotus citrinopileatus: Inhibition of MAPK and NF-κB Signaling Pathways, and Activation of ROS/PI3K/Nrf2/HO-1 Signaling Pathway in LPS-Stimulated RAW264.7 Cells., PMID:40374537
Expression and diagnostic values of ferroptosis-related genes in coronavirus-associated viral sepsis., PMID:40370730
Dihydromyricetin mitigates abdominal aortic aneurysm via transcriptional and post-transcriptional regulation of heme oxygenase-1 in vascular smooth muscle cells., PMID:40370559
The NFE2L2 (NRF2) transcription factor controls genes involved in the oxidative stress response and inflammation in myometrial cells., PMID:40360022
NFE2L3 regulates inflammation and oxidative stress-related genes in the colon., PMID:40360021
Dracorhodin perochlorate sensitizes colorectal cancer to ferroptosis by activating HMOX1 and inhibiting the SLC7A11/GPX4 axis., PMID:40359890
Canagliflozin Delays Aortic Valve Calcification by Enhancing the AMPK/Nrf2/HO-1 Antioxidant Signaling Pathway in Valvular Interstitial Cells., PMID:40357866
Syringic acid alleviates cadmium-induced neurotoxicity in rats by modulating cellular signaling pathways., PMID:40354709