Catalog No.
RHE04202
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
MCM4, CDC21 homolog, CDC21, P1-CDC21, DNA replication licensing factor MCM4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P33991
Applications
FCM, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1U70
EZH2 regulates pancreatic cancer cells through E2F1, GLI1, CDK3, and Mcm4., PMID:37198697
Comparative Study of the Minichromosome Maintenance Proteins Complex (MCM 4/5/6) in Ameloblastoma and Unicystic Ameloblastoma., PMID:29845895
Effect of daidzein and equol on DNA replication in MCF-7 cells., PMID:29346578
Characterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA., PMID:21829589
Increase of Mcm3 and Mcm4 expression in cervical squamous cell carcinomas., PMID:21077471
Functional cooperation between FACT and MCM is coordinated with cell cycle and differential complex formation., PMID:20156367
Minichromosome maintenance proteins are useful adjuncts to differentiate between benign and malignant melanocytic skin lesions., PMID:19389522
Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells., PMID:18286467
Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin., PMID:17046832
The medulloblastoma cell line DAOY but not eleven other tumor cell lines expresses minichromosome maintenance protein 4., PMID:16051427
A hypophosphorylated form of RPA34 is a specific component of pre-replication centers., PMID:15456845
Human Mcm proteins at a replication origin during the G1 to S phase transition., PMID:12364596
Essential role of human CDT1 in DNA replication and chromatin licensing., PMID:11896191
Identification of a binding region for human origin recognition complex proteins 1 and 2 that coincides with an origin of DNA replication., PMID:11809796
Phosphorylation of Mcm4 at specific sites by cyclin-dependent kinase leads to loss of Mcm4,6,7 helicase activity., PMID:11454864
Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis., PMID:11046155
Localisation of the DmCdc45 DNA replication factor in the mitotic cycle and during chorion gene amplification., PMID:11024168
Stepwise regulated chromatin assembly of MCM2-7 proteins., PMID:10722676
Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis., PMID:10491086
Multiple domains of fission yeast Cdc19p (MCM2) are required for its association with the core MCM complex., PMID:9658174
A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex., PMID:9305914
Binding of human minichromosome maintenance proteins with histone H3., PMID:8798650
A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins., PMID:7601140
The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins., PMID:8265339
For research use only. Not for human or drug use.
