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Anti-CD50/ICAM3 Antibody (R1U60)

Catalog #:   RHE01702 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IHC, IP, WB
Accession: P32942
Overview

Catalog No.

RHE01702

Species reactivity

Human, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000

Target

CD50, CDw50, Intercellular adhesion molecule 3, ICAM-R, ICAM3, ICAM-3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P32942

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1U60

Note

For research use only.

Data Image
  • Immunohistochemical
    Immunohistochemistry analysis of paraffin-embedded Human tonsil using ICAM3 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot
    Western blot analysis of ICAM3 in Hela, A549, HL-60, U2OS, C6 lysates using ICAM3 antibody.
References

Beta1 integrin triggering affects leukemic cell line sensitivity to natural killer cells., PMID:11941451

Functional evaluation of DC-SIGN monoclonal antibodies reveals DC-SIGN interactions with ICAM-3 do not promote human immunodeficiency virus type 1 transmission., PMID:12021323

Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN, CD209), a C-type surface lectin in human DCs, is a receptor for Leishmania amastigotes., PMID:12122001

Immunophenotypic analysis of human spleen compartments., PMID:12392323

Differential pathomechanisms of epidermal necrolytic blistering diseases., PMID:12429994

Adhesion molecules as costimulators: ICAM-3 signaling potentiates CD3-mediated HIV-1 stimulation., PMID:12485933

Functional antibodies to leukocyte adhesion molecules in antithymocyte globulins., PMID:12640305

The Prognosis of Survival in Patients with Some Solid Tumors Based on Optimal Partitions of Immunological Parameter Ranges., PMID:12687164

Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses., PMID:12783086

ICAM-3 activation modulates cell-cell contacts of human bone marrow endothelial cells., PMID:14726630

[Dynamics of the soluble CD50-antigen level in patients with breast cancer in the course of combined therapy]., PMID:15137202

Immunohistochemical study of cyclosporin-induced gingival overgrowth in renal transplant recipients., PMID:15732868

Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin., PMID:15940144

Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding., PMID:15958383

[Linear and adhesive phenotype of tumor lymphocytes and clinical course of chronic leucosis]., PMID:15960204

[Serum level of soluble forms of membranous antigens of immune system cells in carriers of virus hepatitis G markers]., PMID:16250593

Effect of a combination of extract from several plants on cell-mediated and humoral immunity of patients with advanced ovarian cancer., PMID:16619374

Ligation of intercellular adhesion molecule 3 induces apoptosis of human blood eosinophils and neutrophils., PMID:17030234

DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues., PMID:17145745

The role of complement regulatory proteins (CD55 and CD59) in the pathogenesis of autoimmune hemocytopenias., PMID:17289551

Mutation of a conserved asparagine in the I-like domain promotes constitutively active integrins alphaLbeta2 and alphaIIbbeta3., PMID:17468108

Tonsil epithelial factors may influence oropharyngeal human immunodeficiency virus transmission., PMID:17620369

Use of flow cytometry to identify monoclonal antibodies that recognize conserved epitopes on orthologous leukocyte differentiation antigens in goats, llamas, and rabbits., PMID:17686528

Evaluation of in vivo and in vitro biological activity of a Vibrio cholerae 01 hemolysin., PMID:18053392

Structural requirements for multimerization of the pathogen receptor dendritic cell-specific ICAM3-grabbing non-integrin (CD209) on the cell surface., PMID:18073208

Glycosphingolipids in vascular endothelial cells: relationship of heterogeneity in Gb3Cer/CD77 receptor expression with differential Shiga toxin 1 cytotoxicity., PMID:18176841

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4., PMID:18377648

Binding of the Streptococcus gordonii DL1 surface protein Hsa to the host cell membrane glycoproteins CD11b, CD43, and CD50., PMID:18678668

Intercellular adhesion molecule 1 (ICAM-1), but not ICAM-2 and -3, is important for dendritic cell-mediated human immunodeficiency virus type 1 transmission., PMID:19211748

Ovarian cancer-derived glycodelin impairs in vitro dendritic cell maturation., PMID:19609241

Phenotyping studies of clonotypic B lymphocytes from patients with multiple myeloma by flow cytometry., PMID:19792049

A mechanistic rationale for combining alemtuzumab and rituximab in the treatment of ALL., PMID:20844239

Adhesion molecules are promising candidates to establish surrogate markers for natalizumab treatment., PMID:20937631

An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells., PMID:21841799

Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells., PMID:22117198

Activated apoptotic cells induce dendritic cell maturation via engagement of Toll-like receptor 4 (TLR4), dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN), and β2 integrins., PMID:22396536

Fludarabine and cladribine induce changes in surface proteins on human B-lymphoid cell lines involved with apoptosis, cell survival, and antitumor immunity., PMID:22839105

Novel role of ICAM3 and LFA-1 in the clearance of apoptotic neutrophils by human macrophages., PMID:23775590

An alternative micromethod to access the procoagulant activity of Bothrops jararaca venom and the efficacy of antivenom., PMID:25128708

Development and characterization of a monoclonal antibody specific for bovine CD209., PMID:25593043

Characterization and expression of monoclonal antibody-defined molecules on resting and activated bovine αβ, γδ T and NK cells., PMID:26384699

Modulation of Proinflammatory Cytokines in Monocyte-Derived Dendritic Cells by Porcine Reproductive and Respiratory Syndrome Virus Through Interaction with the Porcine Intercellular-Adhesion-Molecule-3-Grabbing Nonintegrin., PMID:27643915

Bispecific chimeric antigen receptors targeting the CD4 binding site and high-mannose Glycans of gp120 optimized for anti-human immunodeficiency virus potency and breadth with minimal immunogenicity., PMID:29306566

ICAM3 mediates tumor metastasis via a LFA-1-ICAM3-ERM dependent manner., PMID:29729315

Transcriptomics and Immunological Analyses Reveal a Pro-Angiogenic and Anti-Inflammatory Phenotype for Decidual Endothelial Cells., PMID:30935090

Chitosan nano-structure loaded with recombinant E. coli O157:H7 antigens as a vaccine candidate can effectively increase immunization capacity., PMID:31240960

Immunophenotypic Characterization and Purification of Neoplastic Cells from Lymph Nodes Involved by T-Cell/Histiocyte-rich Large B-cell Lymphoma by Flow Cytometry and Flow Cytometric Cell Sorting., PMID:31254446

An approach to chimeric subunit immunogen provides efficient protection against toxicity, type III and type v secretion systems of Shigella., PMID:34508943

Unraveling the surface proteomic profile of multiple myeloma to reveal new immunotherapeutic targets and markers of drug resistance., PMID:36311892

Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-CD50/ICAM3 Antibody (R1U60) [RHE01702]
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