Catalog No.
YHC40701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gln338
Predicted molecular weight
39.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09467
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FBPase 1, FBP1, Liver FBPase, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1, FBP, Fructose-1,6-bisphosphatase 1
HNF4α-TET2-FBP1 axis contributes to gluconeogenesis and type 2 diabetes., PMID:40459008
O-GlcNAcylation of FBP1 promotes pancreatic cancer progression by facilitating its Lys48-linked polyubiquitination in hypoxic environments., PMID:40263262
Multiomics analysis of human serum and animal experiments reveals the protective mechanism of Qingre Huoxue Decoction against rheumatoid arthritis., PMID:40124380
ChREBP mediates metabolic remodeling in FBP1-deficient liver., PMID:40055186
Glucose and Insulin Differently Regulate Gluconeogenic and Ureagenic Gene Expression., PMID:40024748
Unveiling the effects of GSK126 on osteosarcoma cells implications for apoptosis, autophagy, and cellular migration., PMID:40014170
Identification and functional analysis of energy metabolism and pyroptosis-related genes in diabetic nephropathy., PMID:39995931
Fructose 1,6-bisphosphatase 1 is a potential biomarker affecting the malignant phenotype and aerobic glycolysis in glioblastoma., PMID:39902328
Fructose-1,6-bisphosphatase 1 in cancer: Dual roles, mechanistic insights, and therapeutic potential - A comprehensive review., PMID:39753180
FBP1 controls liver cancer evolution from senescent MASH hepatocytes., PMID:39743585
Salvianolic acid C promotes renal gluconeogenesis in fibrotic kidneys through PGC1α., PMID:39700761
Fructose-1,6-diphosphate inhibits viral replication by promoting the lysosomal degradation of HMGB1 and blocking the binding of HMGB1 to the viral genome., PMID:39693295
FBP1 over-expression suppresses HIF-1α in papillary thyroid cancer., PMID:39587225
Fructose 1,6-bisphosphatase as a promising target of anticancer treatment., PMID:39490352
Overexpression of FBP1 enhances dendritic cell activation and maturation by inhibiting glycolysis and promoting the secretion of IL33 in lung adenocarcinoma., PMID:39486659
TRIM47 promotes the Warburg effect and reduces ferroptosis in prostate cancer by FBP1 and FOXO1., PMID:39434735
Glycogenesis and glyconeogenesis from glutamine, lactate and glycerol support human macrophage functions., PMID:39424955
GSM1 Requires Hap4 for Expression and Plays a Role in Gluconeogenesis and Utilization of Nonfermentable Carbon Sources., PMID:39336719
Innate cells and STAT1-dependent signals orchestrate vaccine-induced protection against invasive Cryptococcus infection., PMID:39324785
Disturbed function of TBL1X has a differential effect on T3-regulated gene expression in two human liver cell models., PMID:39316725
Fermentation impact: A comparative study on the functional and biological properties of Banana peel waste., PMID:39247352
PI3KR1 and AKT1 in largemouth bass (Micropterus salmoides): molecular cloning, characterization, and its involvement in the alleviation of hepatic glycogen deposition caused by insulin inclusion in vitro., PMID:39150597
Distinct maturation, glucose metabolism, and inflammatory function of human monocytes-derived IDECs mediated by anti-IgE and Pam3CSK4 alone or in combination., PMID:39086490
Exposure to 6-PPD quinone disrupts glucose metabolism associated with lifespan reduction by affecting insulin and AMPK signals in Caenorhabditis elegans., PMID:39084302
Huaier inhibits cholangiocarcinoma cells through the twist1/FBP1/Wnt/β-catenin axis., PMID:39042261
Inhibition of FBP1 expression by KMT5A through TWIST1 methylation is one of the mechanisms leading to chemoresistance in breast cancer., PMID:38963044
Research into how carvacrol and metformin affect several human proteins in a hyperglycemic condition: A comparative study in silico and in vitro., PMID:38880320
FBP1 orchestrates keratinocyte proliferation/differentiation and suppresses psoriasis through metabolic control of histone acetylation., PMID:38834617
Transcriptome analysis of adipose tissue and muscle of Laiwu and Duroc pigs., PMID:38766520
Identification and functional analysis of lactic acid metabolism-related differentially expressed genes in hepatocellular carcinoma., PMID:38689649
Fructose-1,6-bisphosphatase 1 dephosphorylates and inhibits TERT for tumor suppression., PMID:38538923
Differential Disruption of Glucose and Lipid Metabolism Induced by Phthalates in Human Hepatocytes and White Adipocytes., PMID:38535947
Excess homocysteine inhibits pancreatic β-cell secretory function by repressing Zbtb20 expression., PMID:38432501
FBP1 inhibits NSCLC stemness by promoting ubiquitination of Notch1 intracellular domain and accelerating degradation., PMID:38349431
Identification of candidate regulatory genes for intramuscular fatty acid composition in pigs by transcriptome analysis., PMID:38347496
Associations between plasma metabolism-associated proteins and future development of giant cell arteritis: results from a prospective study., PMID:38310345
Metabolic stress-induced long ncRNA transcription governs the formation of meiotic DNA breaks in the fission yeast fbp1 gene., PMID:38252660
Hypoxia-induced P4HA1 overexpression promotes post-ischemic angiogenesis by enhancing endothelial glycolysis through downregulating FBP1., PMID:38238754
LncRNA SOX9-AS1 triggers a transcriptional program involved in lipid metabolic reprogramming, cell migration and invasion in triple-negative breast cancer., PMID:38233470
The translational potential of miR-26 in atherosclerosis and development of agents for its target genes ACC1/2, COL1A1, CPT1A, FBP1, DGAT2, and SMAD7., PMID:38195542
Extracellular vesicles released by cancer-associated fibroblast-induced myeloid-derived suppressor cells inhibit T-cell function., PMID:38192443
Correction: Fructose‑bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3)., PMID:38155346
Yeast zinc cluster transcription factors involved in the switch from fermentation to respiration show interdependency for DNA binding revealing a novel type of DNA recognition., PMID:38109318
The preferential utilization of hepatic glycogen as energy substrates in largemouth bass (Micropterus salmoides) under short-term starvation., PMID:38108936
Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3)., PMID:38049890
Proteome profiling identifies circulating biomarkers associated with hepatic steatosis in subjects with Prader-Willi syndrome., PMID:38034016
Integrated single-cell and bulk RNA sequencing analysis identifies a neoadjuvant chemotherapy-related gene signature for predicting survival and therapy in breast cancer., PMID:37996875
1α,25(OH)2D3 ameliorates insulin resistance by alleviating γδ T cell inflammation via enhancing fructose-1,6-bisphosphatase 1 expression., PMID:37908738
Effects of Mealworm Fermentation Extract and Soy Protein Mix Ratio on Hepatic Glucose and Lipid Metabolism in Obese-Induced Mice., PMID:37842251
Adipocyte-derived exosomes promote the progression of triple-negative breast cancer through circCRIM1-dependent OGA activation., PMID:37775001
For research use only. Not for human or drug use.
