Catalog No.
RHD87301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Disulfide isomerase ER-60, ER protein 60, ERp60, Endoplasmic reticulum resident protein 57, ERp57, ERP60, p58, Protein disulfide-isomerase A3, ER protein 57, ERP57, PDIA3, Endoplasmic reticulum resident protein 60, GRP58, 58 kDa glucose-regulated protein, 58 kDa microsomal protein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P30101
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1T92
Unveiling the link: anti-protein disulfide isomerase A3 autoantibody expression and polycystic ovary syndrome risk in euthyroid autoimmune thyroiditis women., PMID:39702372
Association Between Peptide Antigen-Related Antibody Levels and the Short- and Long-Term Efficacy of Antipsychotic Treatment in Drug-Naïve First-Episode Schizophrenia Patients., PMID:39673496
The protein disulfide isomerase A3 and osteopontin axis promotes influenza-induced lung remodelling., PMID:39118388
Dual role of the peptide-loading complex as proofreader and limiter of MHC-I presentation., PMID:38771881
PDIA3 driven STAT3/PD-1 signaling promotes M2 TAM polarization and aggravates colorectal cancer progression., PMID:38761176
Inducing Melanoma Cell Apoptosis by ERp57/PDIA3 Antibody in the Presence of CPI-613 and Hydroxychloroquine., PMID:38434963
A Novel Strategy for Selective Thyroid Hormone Determination Based on an Electrochemical Biosensor with Graphene Nanocomposite., PMID:36679398
PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes., PMID:35984892
Patient-Derived Extracellular Vesicles Proteins as New Biomarkers in Multiple Myeloma - A Real-World Study., PMID:35800053
A Predictive Role of Autoantibodies Against the Epitope aa168-183 of ENO1 in the Occurrence of Miscarriage Related to Thyroid Autoimmunity., PMID:35707546
The expression of anti-protein disulfide isomerase A3 autoantibody is associated with the increased risk of miscarriage in euthyroid women with thyroid autoimmunity., PMID:34996009
Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature., PMID:34372761
Dermatan Sulfate Is a Potential Regulator of IgH via Interactions With Pre-BCR, GTF2I, and BiP ER Complex in Pre-B Lymphoblasts., PMID:34113352
Differential expression of protein disulfide isomerase (PDI) in regulating endometrial receptivity in humans., PMID:33677360
ER-resident oxidoreductases are glycosylated and trafficked to the cell surface to promote matrix degradation by tumour cells., PMID:33077910
UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD., PMID:32558906
Disulfide isomerase ERp57 improves the stability and immunogenicity of H3N2 influenza virus hemagglutinin., PMID:32316996
The role of protein disulphide-isomerase A3 as autoantigen in the pathogenesis of autoimmune thyroiditis and related brain damage in adult mice., PMID:31982645
The role of PDIA3 in myogenesis during muscle regeneration., PMID:31956274
Effects of calcium-dependent molecular chaperones and endoplasmic reticulum in the amygdala in rats under single‑prolonged stress., PMID:29115545
A decision tree-based combination of ezrin-interacting proteins to estimate the prognostic risk of patients with esophageal squamous cell carcinoma., PMID:28603065
The roles of protein disulphide isomerase family A, member 3 (ERp57) and surface thiol/disulphide exchange in human spermatozoa-zona pellucida binding., PMID:28175305
An ERp57-mediated disulphide exchange promotes the interaction between Burkholderia cenocepacia and epithelial respiratory cells., PMID:26879174
Protein disulfide isomerase A3-specific Th1 effector cells infiltrate colon cancer tissue of patients with circulating anti-protein disulfide isomerase A3 autoantibodies., PMID:26772958
Redox proteomics identification of specifically carbonylated proteins in the hippocampi of triple transgenic Alzheimer's disease mice at its earliest pathological stage., PMID:25890254
GFAP antibodies show protective effect on oxidatively stressed neuroretinal cells via interaction with ERP57., PMID:25837926
The dehydrogenase region of the NADPH oxidase component Nox2 acts as a protein disulfide isomerase (PDI) resembling PDIA3 with a role in the binding of the activator protein p67 (phox.)., PMID:25699251
Proapoptotic activities of protein disulfide isomerase (PDI) and PDIA3 protein, a role of the Bcl-2 protein Bak., PMID:25697356
Trichinella spiralis: genome database searches for the presence and immunolocalization of protein disulphide isomerase family members., PMID:25475092
Membrane actions of 1α,25(OH)2D3 are mediated by Ca(2+)/calmodulin-dependent protein kinase II in bone and cartilage cells., PMID:25263660
Rapid 1α,25(OH)₂D ₃ membrane-mediated activation of Ca²⁺/calmodulin-dependent protein kinase II in growth plate chondrocytes requires Pdia3, PLAA and caveolae., PMID:25158196
The disulfide isomerase ERp57 is required for fibrin deposition in vivo., PMID:25156521
Identification and characterization of an oocyte factor required for sperm decondensation in pig., PMID:25030891
Identification of target antigens of anti-endothelial cell antibodies in patients with anti-neutrophil cytoplasmic antibody-associated vasculitides: a proteomic approach., PMID:24726766
The binding of silibinin to ERp57., PMID:24530445
Increased expression of ERp57 in rat oocytes during meiotic maturation is associated with sperm-egg fusion., PMID:24415168
Glycan-dependent and -independent interactions contribute to cellular substrate recruitment by calreticulin., PMID:24100026
Secretion of ERP57 is important for extracellular matrix accumulation and progression of renal fibrosis, and is an early sign of disease onset., PMID:23781031
The protein ERp57 contributes to EGF receptor signaling and internalization in MDA-MB-468 breast cancer cells., PMID:23696074
Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway., PMID:23401559
Diosgenin is an exogenous activator of 1,25D₃-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice., PMID:22837815
Role of the 1,25D3-MARRS receptor in the 1,25(OH)2D3-stimulated uptake of calcium and phosphate in intestinal cells., PMID:22546984
Serendipitous discovery of a novel protein signaling mechanism in heart failure., PMID:22503978
Phospholipase A2 activating protein is required for 1α,25-dihydroxyvitamin D3 dependent rapid activation of protein kinase C via Pdia3., PMID:22484374
Intestinal cell phosphate uptake and the targeted knockout of the 1,25D3-MARRS receptor/PDIA3/ERp57., PMID:22334724
The role of the vitamin D receptor and ERp57 in photoprotection by 1α,25-dihydroxyvitamin D3., PMID:22322599
The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function., PMID:22168334
Immunoproteomic analysis of the antibody response obtained in mouse following vaccination with a T-cell vaccine., PMID:21919206
Role of cysteine amino acid residues in calnexin., PMID:21842374
Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells., PMID:21093319
For research use only. Not for human or drug use.
