Catalog No.
RHD79601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Dual specificity protein phosphatase 1, MAP kinase phosphatase 1, CL100, PTPN10, Mitogen-activated protein kinase phosphatase 1, MKP1, MKP-1, DUSP1, Protein-tyrosine phosphatase CL100, VH1, Dual specificity protein phosphatase hVH1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P28562
Applications
FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1T60
Multi-omic characteristics of longitudinal immune profiling after breakthrough infections caused by Omicron BA.5 sublineages., PMID:39536392
Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases., PMID:39284741
Expression profile of mRNAs and miRNAs related to mitogen-activated kinases in HaCaT cell culture treated with lipopolysaccharide a and adalimumab., PMID:38557266
Chronic TNF exposure induces glucocorticoid-like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia., PMID:38459711
Seven chromatin regulators as immune cell infiltration characteristics, potential diagnostic biomarkers and drugs prediction in hepatocellular carcinoma., PMID:37903974
Aloe-emodin targets multiple signaling pathways by blocking ubiquitin-mediated degradation of DUSP1 in nasopharyngeal carcinoma cells., PMID:36866539
Evaluation of molecular apoptosis signaling pathways and its correlation with EBV viral load in SLE patients using systems biology approach., PMID:34864653
Changes in the Expression Pattern of DUSP1-7 and miRNA Regulating their Expression in the Keratinocytes Treated with LPS and Adalimumab., PMID:34342258
β-Caryophyllene attenuates lipopolysaccharide-induced acute lung injury via inhibition of the MAPK signalling pathway., PMID:34313776
Serum microRNAs as Tool to Predict Early Response to Benralizumab in Severe Eosinophilic Asthma., PMID:33525548
Genetic Basis of Response of Ghanaian Local Chickens to Infection With a Lentogenic Newcastle Disease Virus., PMID:32849779
Glucocorticoid Receptor-α and MKP-1 as Candidate Biomarkers for Treatment Response and Disease Activity in Vogt-Koyanagi-Harada Disease., PMID:31323199
Glucocorticoid Receptor Modulates EGFR Feedback upon Acquisition of Resistance to Monoclonal Antibodies., PMID:31052457
Immune profiling of pre- and post-treatment breast cancer tissues from the SWOG S0800 neoadjuvant trial., PMID:30967156
Paclitaxel reversed trastuzumab resistance via regulating JUN in human gastric cancer cells identified by FAN analysis., PMID:30265158
Obacunone causes sustained expression of MKP-1 thus inactivating p38 MAPK to suppress pro-inflammatory mediators through intracellular MIF., PMID:28657665
CpG oligonucleotide-mediated co-stimulation of mouse invariant natural killer T cells negatively regulates their activation status., PMID:28550425
Corticosteroid modulation of immunoglobulin expression and B-cell function in COPD., PMID:26887440
Heparin Decreases in Tumor Necrosis Factor α (TNFα)-induced Endothelial Stress Responses Require Transmembrane Protein 184A and Induction of Dual Specificity Phosphatase 1., PMID:26769965
Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis., PMID:26655499
Sustained interleukin-1β exposure modulates multiple steps in glucocorticoid receptor signaling, promoting split-resistance to the transactivation of prominent anti-inflammatory genes by glucocorticoids., PMID:25977599
Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults., PMID:25367297
Critical role of MKP-1 in lipopolysaccharide-induced osteoclast formation through CXCL1 and CXCL2., PMID:25261746
Post-translational regulation of mitogen-activated protein kinase phosphatase (MKP)-1 and MKP-2 in macrophages following lipopolysaccharide stimulation: the role of the C termini of the phosphatases in determining their stability., PMID:25204653
LC3 binding to the scaffolding protein JIP1 regulates processive dynein-driven transport of autophagosomes., PMID:24914561
[Preliminary study of apoptotic inhibition and its molecular mechanism of dexamethasone on cisplatin-induced human lung adenocarcinoma cell line SPCA/I]., PMID:24490498
MAPK signaling drives inflammation in LPS-stimulated cardiomyocytes: the route of crosstalk to G-protein-coupled receptors., PMID:23226236
The expression of dual-specificity phosphatase 1 mRNA is downregulated in lesional psoriatic skin., PMID:22924482
Differential expression and functional analysis of the tristetraprolin family during early differentiation of 3T3-L1 preadipocytes., PMID:22701344
Mite allergen Der-p2 triggers human B lymphocyte activation and Toll-like receptor-4 induction., PMID:21909400
Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells., PMID:21263446
Transcriptional regulation of human dual specificity protein phosphatase 1 (DUSP1) gene by glucocorticoids., PMID:21060794
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors., PMID:20837666
Phase I/II trial of bevacizumab and radiotherapy for locally advanced inoperable colorectal cancer: vasculature-independent radiosensitizing effect of bevacizumab., PMID:19887481
Identification of protein tyrosine phosphatases and dual-specificity phosphatases in mammalian spermatozoa and their role in sperm motility and protein tyrosine phosphorylation., PMID:19211810
Unique co-expression of immune cell-related genes in IBDV resistant chickens indicates the activation of specific cellular host-response mechanisms., PMID:18817297
IL-4-induced Stat6 activities affect apoptosis and gene expression in breast cancer cells., PMID:18342537
VEGF and thrombin induce MKP-1 through distinct signaling pathways: role for MKP-1 in endothelial cell migration., PMID:18003751
Acetylation of histone H3 and adrenergic-regulated gene transcription in rat pinealocytes., PMID:17628002
Dexamethasone suppresses monocyte chemoattractant protein-1 production via mitogen activated protein kinase phosphatase-1 dependent inhibition of Jun N-terminal kinase and p38 mitogen-activated protein kinase in activated rat microglia., PMID:17403137
Dipyridamole activation of mitogen-activated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells., PMID:16765938
Molecular events triggered by heat shock in Y1 adrenocortical cells., PMID:15666808
Regulation of connexin43-protein binding in astrocytes in response to chemical ischemia/hypoxia., PMID:15618229
Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids., PMID:15476200
Repression of mitogen-activated protein kinase (MAPK) phosphatase-1 by anthracyclines contributes to their antiapoptotic activation of p44/42-MAPK., PMID:14557375
MAP kinase phosphatase-1 is induced in abnormal fibers in inclusion body myositis., PMID:12913191
Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer., PMID:12618338
Molecular mechanisms of non-apoptosis by Fas stimulation alone versus apoptosis with an additional actinomycin D in cultured cardiomyocytes., PMID:12176128
Expression of mitogen-activated protein kinases in human renal dysplasia., PMID:11849444
Insulin-induced c-Jun N-terminal kinase activation is negatively regulated by protein kinase C delta., PMID:11356718
For research use only. Not for human or drug use.
