Catalog No.
YHC38801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly182-Asn424
Predicted molecular weight
27.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09110
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Peroxisomal 3-oxoacyl-CoA thiolase, Acetyl-CoA C-myristoyltransferase, Acetyl-CoA acyltransferase, ACAA, 3-ketoacyl-CoA thiolase, peroxisomal, Beta-ketothiolase, ACAA1, PTHIO
Compound 3d Attenuates Metabolic Dysfunction-Associated Steatohepatitis via Peroxisome Proliferator-Activated Receptor Pathway Activation and Inhibition of Inflammatory and Apoptotic Signaling., PMID:40422873
Cross-ancestry genome-wide association study identifies new susceptibility genes for preeclampsia., PMID:40170147
Effects of different energy levels in low-protein diet on liver lipid metabolism in the late-phase laying hens through the gut-liver axis., PMID:38987834
Gestational organophosphate esters (OPEs) exposure in association with placental DNA methylation levels of peroxisome proliferator-activated receptors (PPARs) signaling pathway-related genes., PMID:38977092
Whole Genome Scan Uncovers Candidate Genes Related to Milk Production Traits in Barka Cattle., PMID:38892330
Mechanisms of low nighttime temperature promote oil accumulation in Brassica napus L. based on in-depth transcriptome analysis., PMID:38812077
Identification of PPAR-related differentially expressed genes liver hepatocellular carcinoma and construction of a prognostic model based on data analysis and molecular docking., PMID:38652093
Multi-omics approaches for drug-response characterization in primary biliary cholangitis and autoimmune hepatitis variant syndrome., PMID:38424613
Proteomic study on nintedanib in gastric cancer cells., PMID:38406279
[Clinical phenotypic and genotypic analysis of 5 pediatric patients with β-ketothiolase deficiency]., PMID:38154980
The Identification of Functional Genes Affecting Fat-Related Meat Traits in Meat-Type Pigeons Using Double-Digest Restriction-Associated DNA Sequencing and Molecular Docking Analysis., PMID:37893980
Appropriate cold stimulation changes energy distribution to improve stress resistance in broilers., PMID:37279534
Inhibition of ACAA1 Restrains Proliferation and Potentiates the Response to CDK4/6 Inhibitors in Triple-Negative Breast Cancer., PMID:37129951
In-depth systems biological evaluation of bovine alveolar macrophages suggests novel insights into molecular mechanisms underlying Mycobacterium bovis infection., PMID:36532492
Autophagy inhibition and reactive oxygen species elimination by acetyl-CoA acetyltransferase 1 through fused in sarcoma protein to promote prostate cancer., PMID:36517760
The Cys-N-degron pathway modulates pexophagy through the N-terminal oxidation and arginylation of ACAD10., PMID:36184612
Mycobacterium tuberculosis Acetyltransferase Suppresses Oxidative Stress by Inducing Peroxisome Formation in Macrophages., PMID:35269727
iTRAQ-based quantitative proteomics analysis of Sprague-Dawley rats liver reveals perfluorooctanoic acid-induced lipid metabolism and urea cycle dysfunction., PMID:34958885
A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline., PMID:34465723
Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis., PMID:34110423
Peroxisomes in the mouse parotid glands: An in-depth morphological and molecular analysis., PMID:34091056
Bioinformatics Analysis of Key Candidate Genes and Pathways in Ulcerative Colitis., PMID:33132321
HSD17B4, ACAA1, and PXMP4 in Peroxisome Pathway Are Down-Regulated and Have Clinical Significance in Non-small Cell Lung Cancer., PMID:32265992
The effects of chronic cadmium exposure on Bufo gargarizans larvae: Histopathological impairment, gene expression alteration and fatty acid metabolism disorder in the liver., PMID:32199138
High-Dose Dexamethasone Manipulates the Tumor Microenvironment and Internal Metabolic Pathways in Anti-Tumor Progression., PMID:32156004
Transcriptomic Responses in the Livers and Jejunal Mucosa of Pigs under Different Feeding Frequencies., PMID:31547261
MicroRNA-15a Regulates the Differentiation of Intramuscular Preadipocytes by Targeting ACAA1, ACOX1 and SCP2 in Chickens., PMID:31434294
Quantitative Proteomic Analysis of Low Linolenic Acid Transgenic Soybean Reveals Perturbations of Fatty Acid Metabolic Pathways., PMID:30784187
Dietary fish oil supplementation alters liver gene expressions to protect against LPS-induced liver injury in weanling piglets., PMID:30782046
Proteomic Analysis of Lysosomal Membrane Proteins in Bovine Mammary Epithelial Cells Illuminates Potential Novel Lysosome Functions in Lactation., PMID:30499671
Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours., PMID:30176945
Selenium Supplementation Alters Hepatic Energy and Fatty Acid Metabolism in Mice., PMID:29982657
hsa-miR-29c-3p regulates biological function of colorectal cancer by targeting SPARC., PMID:29262657
Proteomics Analysis Reveals an Important Role for the PPAR Signaling Pathway in DBDCT-Induced Hepatotoxicity Mechanisms., PMID:28684700
Differential activities of peroxisomes along the mouse intestinal epithelium., PMID:28370438
Aberrant expression of cell cycle and material metabolism related genes contributes to hepatocellular carcinoma occurrence., PMID:28238542
Pyrazinamide induced hepatic injury in rats through inhibiting the PPARα pathway., PMID:27071702
Identification of hepatocellular carcinoma-associated hub genes and pathways by integrated microarray analysis., PMID:25768320
Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways., PMID:25605240
Ananas comosus L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression., PMID:25197313
Polymorphisms in genes involved in fatty acid β-oxidation interact with dietary fat intakes to modulate the plasma TG response to a fish oil supplementation., PMID:24647074
Functional TLR5 genetic variants affect human colorectal cancer survival., PMID:24154872
Tysnd1 deficiency in mice interferes with the peroxisomal localization of PTS2 enzymes, causing lipid metabolic abnormalities and male infertility., PMID:23459139
Innate immunity and non-Hodgkin's lymphoma (NHL) related genes in a nested case-control study for gastric cancer risk., PMID:23028900
Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1., PMID:22151743
Molecular markers of endometrial carcinoma detected in uterine aspirates., PMID:21207424
Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice., PMID:17717280
Underlying mechanisms of pharmacology and toxicity of a novel PPAR agonist revealed using rodent and canine hepatocytes., PMID:17255113
For research use only. Not for human or drug use.
