Catalog No.
RHD58501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
LRN, LOR, Loricrin, LORICRIN
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P23490
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1S40
Regulatory effects of Ishige okamurae extract and Diphlorethohydroxycarmalol on skin barrier function., PMID:39654745
Evaluation of the therapeutic effect of Sacha inchi oil in atopic dermatitis mice., PMID:38917521
Topical application of Artemisia annua L. essential oil ameliorates 2,4-dintrochlorobenzene-induced atopic dermatitis in mice., PMID:38862031
(S)-(-)-blebbistatin O-benzoate has the potential to improve atopic dermatitis symptoms in NC/Nga mice by upregulating epidermal barrier function and inhibiting type 2 alarmin cytokine induction., PMID:38713650
Targeting IL-13 with tralokinumab normalizes type 2 inflammation in atopic dermatitis both early and at 2 years., PMID:38563683
Comparative immunohistochemical analysis suggests a conserved role of EPS8L1 in epidermal and hair follicle barriers of mammals., PMID:37889356
Ablation of Basic Leucine Zipper Transcription Factor ATF-Like Potentiates Estradiol to Induce Atopic Dermatitis., PMID:36160706
Lithospermum erythrorhizon Alleviates Atopic Dermatitis-like Skin Lesions by Restoring Immune Balance and Skin Barrier Function in 2.4-Dinitrochlorobenzene-Induced NC/Nga Mice., PMID:34579088
Efficacy and action mechanisms of a Chinese herbal formula on experimental models of atopic dermatitis., PMID:33716079
Evaluation of the Efficacy of Loricrin as a Diagnostic Marker in Patients with Oral Submucous Fibrosis., PMID:33149468
Effects of Apigenin on RBL-2H3, RAW264.7, and HaCaT Cells: Anti-Allergic, Anti-Inflammatory, and Skin-Protective Activities., PMID:32610574
The Effects of Fabric Containing Chamaecyparis obtusa Essential Oil on Atopic Dermatitis-Like Lesions: A Functional Clothing Possibility., PMID:32535609
Caffeoyl-Pro-His amide relieve DNCB-Induced Atopic Dermatitis-Like phenotypes in BALB/c mice., PMID:32439906
Development of an in vitro submerged culture system to synthesize epidermal ceramides in canine keratinocytes., PMID:32143083
Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation., PMID:32019420
Fermented Morinda citrifolia (Noni) Alleviates DNCB-Induced Atopic Dermatitis in NC/Nga Mice through Modulating Immune Balance and Skin Barrier Function., PMID:31963703
Poncirus Trifoliata (L.) Raf. Extract Inhibits the Development of Atopic Dermatitis-like Lesions in Human Keratinocytes and NC/Nga mice., PMID:31523174
Lysates of a Probiotic, Lactobacillus rhamnosus, Can Improve Skin Barrier Function in a Reconstructed Human Epidermis Model., PMID:31480681
Loricrin expression and its implication in oral submucous fibrosis, hyperkeratosis and normal mucosa with association to habits - An immunohistochemical study., PMID:31193624
Atopic dermatitis in African American patients is TH2/TH22-skewed with TH1/TH17 attenuation., PMID:30223113
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis., PMID:30194992
Eupatilin, an activator of PPARα, inhibits the development of oxazolone-induced atopic dermatitis symptoms in Balb/c mice., PMID:29353040
Acidification of stratum corneum prevents the progression from atopic dermatitis to respiratory allergy., PMID:27376923
Transcription factor 7-like 1 dysregulates keratinocyte differentiation through upregulating lipocalin 2., PMID:27551519
Interleukin-15 inhibits the expression of differentiation markers induced by Ca(2+) in keratinocytes., PMID:26914593
Immunolocalization of loricrin in the maturing α-layer of normal and regenerating epidermis of the lizard Anolis carolinensis., PMID:25690302
Staphylococcus aureus inhibits terminal differentiation of normal human keratinocytes by stimulating interleukin-6 secretion., PMID:24398033
Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis., PMID:23777851
Ultrastructural immunocytochemistry for the central region of keratin associated-beta-proteins (beta-keratins) shows the epitope is constantly expressed in reptilian epidermis., PMID:23608345
Epidermal structure created by canine hair follicle keratinocytes enriched with bulge cells in a three-dimensional skin equivalent model in vitro: implications for regenerative therapy of canine epidermis., PMID:23331683
Cornification in reptilian epidermis occurs through the deposition of keratin-associated beta-proteins (beta-keratins) onto a scaffold of intermediate filament keratins., PMID:23065677
Location of Keratin-associated Proteins in Developing Fiber Cuticle Cells using Immunoelectron Microscopy., PMID:21712910
TRPV1 antagonist can suppress the atopic dermatitis-like symptoms by accelerating skin barrier recovery., PMID:21345654
Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators., PMID:20930145
Comprehensive keratin profiling reveals different histopathogenesis of keratocystic odontogenic tumor and orthokeratinized odontogenic cyst., PMID:20801488
Disturbed keratin expression and distinct genotype of ichthyosis hystrix Lambert type., PMID:20605767
The potency of the fs260 connexin43 mutant to impair keratinocyte differentiation is distinct from other disease-linked connexin43 mutants., PMID:20515445
Investigation of papulopustular eruptions caused by cetuximab treatment shows altered differentiation markers and increases in inflammatory cytokines., PMID:19903175
Locus 1q21 Gene expression changes in atopic dermatitis skin lesions: deregulation of small proline-rich region 1A., PMID:19672094
Laser capture microscopy in a study of expression of structural proteins in the cuticle cells of human hair., PMID:19220452
Characterization of keratins and associated proteins involved in the corneification of crocodilian epidermis., PMID:17707449
Targeting TNFalpha rapidly reduces density of dendritic cells and macrophages in psoriatic plaques with restoration of epidermal keratinocyte differentiation., PMID:17689932
Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges., PMID:17671515
Hyaluronate fragments reverse skin atrophy by a CD44-dependent mechanism., PMID:17177600
Expression and regulation of cornified envelope proteins in human corneal epithelium., PMID:16639001
SLURP-2: A novel cholinergic signaling peptide in human mucocutaneous epithelium., PMID:16575903
Immunocytochemical observations on the cornification of soft and hard epidermis in the turtle Chrysemys picta., PMID:16351854
Large haematoxylin-stainable keratohyaline granules in solar keratoses: immunohistochemical comparison using anti-Ted-H-1 antibody and antiloricrin antibody., PMID:16225609
Distribution and characterization of proteins associated with cornification in the epidermis of gecko lizard., PMID:16171836
Localization and characterization of specific cornification proteins in avian epidermis., PMID:15812148