Catalog No.
YHC36401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu117-Arg419
Predicted molecular weight
37.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08779
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Keratin, type I cytoskeletal 16, KRT16A, Keratin-16, CK-16, Cytokeratin-16, KRT16, K16
Berberine in the treatment of radiation-induced skin injury: insights from proteomics and network pharmacology., PMID:40421220
Genetic Distinctiveness in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma Cancer: Identifying Key Genomic Signatures through Differentially Expressed Gene Analysis., PMID:40415318
Identification and validation of shared biomarkers and drug repurposing in psoriasis and Crohn's disease: integrating bioinformatics, machine learning, and experimental approaches., PMID:40406126
Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells., PMID:40257786
IL-17 Ligand and Receptor Family Members Are Differentially Expressed by Keratinocyte Subpopulations and Modulate Their Differentiation and Inflammatory Phenotype., PMID:40243580
Sakuranetin modulates IL-17A-related inflammation and enhances skin barrier function in an imiquimod-induced psoriasis model., PMID:40209307
Identifying transcriptomic predictors of brodalumab response in psoriasis using CART analysis., PMID:40140063
Identification of KRT16 and ANXA10 as cell cycle regulation genes for lung adenocarcinoma based on self-transcriptome sequencing of surgical samples and TCGA public data mining., PMID:39841389
Keratin 16 spatially inhibits type I interferon responses in stressed skin., PMID:39763960
Mass spectrometric detection of keratins in tear fluid., PMID:39761842
Clinical and Genetic Findings in Patients With Palmoplantar Keratoderma., PMID:39630431
Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice., PMID:39608053
CSF1-dependent macrophage support matrisome and epithelial stress-induced keratin remodeling in Eosinophilic esophagitis., PMID:39343055
Analysis of intracellular communication reveals consistent gene changes associated with early-stage acne skin., PMID:39143467
Single-cell RNA sequencing comparison of CD4+, CD8+ and T-cell receptor γδ+ cutaneous T-cell lymphomas reveals subset-specific molecular phenotypes., PMID:39133553
Comprehensive analysis of aberrantly methylated differentially expressed genes and validation of CDC6 in melanoma., PMID:39052109
Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high-dose dietary zinc as a therapeutic agent., PMID:39046322
Adenosine A2A receptor activation regulates the M1 macrophages activation to initiate innate and adaptive immunity in psoriasis., PMID:39002795
Pachyonychia congenita: A father and son with a novel variant in the KRT16 gene., PMID:38978313
GLI Transcriptional Targets S100A7 and KRT16 Show Upregulated Expression Patterns in Epidermis Overlying the Tumor Mass in Melanoma Samples., PMID:38892279
LncRNA MIR181A2HG inhibits keratinocytes proliferation through miR-223-3p/SOX6 axis., PMID:38848163
miR-181a/b-5p negatively regulates keratinocytes proliferation by targeting MELK., PMID:38795158
LncRNA MIR181A2HG negatively regulates human keratinocytes proliferation by binding SRSF1., PMID:38736729
Identification of a shared gene signature and biological mechanism between diabetic foot ulcers and cutaneous lupus erythemnatosus by transcriptomic analysis., PMID:38434138
Integrated genetic analysis of diabetic complications: Bioinformatics insights into foot ulcers, neuropathy and peripheral artery disease., PMID:38358067
Evaluation of Cd-induced cytotoxicity in primary human keratinocytes., PMID:38174414
Autosomal recessive plantar keratoderma with ragged periungual hyperkeratosis caused by a homozygous missense variant in KRT16., PMID:38170465
Understanding the effects of per- and polyfluoroalkyl substances on early skin development: Role of ciliogenesis inhibition and altered microtubule dynamics., PMID:38163615
Effect of abrocitinib on skin biomarkers in patients with moderate-to-severe atopic dermatitis., PMID:38108208
A recurrent missense mutation in the KRT16 gene causing pachyonychia congenita in a patient., PMID:38093419
Pachyonychia Congenita Project: Advancing Research and Drug Development through Collaboration., PMID:38072449
Comparative study on gene expression in psoriatic lesions versus chronic wound healing processes., PMID:38012097
Eukaryotic Initiation Factor 4E (eIF4E) as a Target of Anti-Psoriatic Treatment., PMID:37865179
Pachyonychia Congenita: Clinical Features and Future Treatments., PMID:37766547
Idiopathic Subglottic Stenosis Is Associated With More Frequent and Abnormal Squamous Metaplasia., PMID:37740367
Co-occurrence of non-alcoholic steatohepatitis exacerbates psoriasis associated with decreased adiponectin expression in a murine model., PMID:37646025
Target and Mechanism of the Xihuang Pill Based on Network Pharmacology for Lung Squamous Cell Carcinoma., PMID:37442189
Comparisons of the protein expressions between high myopia and moderate myopia on the anterior corneal stroma in human., PMID:37389637
Epidermal Loss of RORα Enhances Skin Inflammation in a MC903-Induced Mouse Model of Atopic Dermatitis., PMID:37373387
Cerebrospinal Fluid Protein Biomarker Discovery in CLN3., PMID:37338096
Targeting the KRT16-vimentin axis for metastasis in lung cancer., PMID:37315823
Detection of the effect of microvibrational stimulation on human discarded immature oocytes by single-cell transcriptome sequencing technology., PMID:37273164
A new prognostic model for RHOV, ABCC2, and CYP4B1 to predict the prognosis and association with immune infiltration of lung adenocarcinoma., PMID:37197482
Elucidating the NB-UVB mechanism by comparing transcriptome alteration on the edge and center of psoriatic plaques., PMID:36928592
Phenotype and genotype features of Vietnamese children with pachyonychia congenita., PMID:36658016
Comprehensive proteomic and phosphoproteomic reveal that Microcystin-LR contributed to the malignant progression of gastric cancer by estrogenic potency., PMID:36436660
miR-204-3p downregulates KRT16 and promotes corneal repair in tree shrew fungal keratitis model., PMID:36398250
Network exploration of gene signatures underlying low birth weight induced metabolic alterations., PMID:36316897
Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling., PMID:36291580
Corneal epithelium in keratoconus underexpresses active NRF2 and a subset of oxidative stress-related genes., PMID:36240204
For research use only. Not for human or drug use.
