Catalog No.
RHD26801
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IP: 1:20, WB: 1:500-1:1000
Target
TREB-5, XBP2, X-box-binding protein 1, Tax-responsive element-binding protein 5, TREB5, XBP1, XBP-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P17861
Applications
IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1Q58
IL16 Promotes Plasma Cell Differentiation., PMID:40495388
Functional multiomics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma., PMID:40453054
Differential Induction of Endoplasmic Reticulum Stress Signaling by Antibody Isotypes: Implications for Plasma Cell Differentiation., PMID:40285383
Suppression of NF-κB and downstream XBP1 by DcR3 contributes to a decrease in antibody secretion., PMID:40073262
A comprehensive analysis of scRNA-Seq and RNA-Seq unveils B cell immune suppression in the AAV-loaded brain., PMID:40044925
Myricetin exposure reduces PC differentiation in vitro in primary human B cells., PMID:39875809
Novel Sarcoidosis Epitope Augments MHCII, CD80/CD86 Expression, Promotes B-Cell Differentiation and IgG Production., PMID:39836049
Assessing human B cell responses to influenza virus vaccines and adjuvants in a PBMC-derived in vitro culture system., PMID:39616951
The Clinical and Molecular Response of Pyoderma Gangrenosum to IL-23 Blockade: Result from a Proof-of-Concept Open-Label Clinical Trial., PMID:39547392
Increased autoreactivity and maturity of EBI2+ antibody-secreting cells from nasal polyps., PMID:39253973
FIND-seq: high-throughput nucleic acid cytometry for rare single-cell transcriptomics., PMID:39039320
Blockade of OX40/OX40L signaling using anti-OX40L alleviates murine lupus nephritis., PMID:38798163
PDIA3 driven STAT3/PD-1 signaling promotes M2 TAM polarization and aggravates colorectal cancer progression., PMID:38761176
The IRE1α/XBP1 pathway sustains cytokine responses of group 3 innate lymphoid cells in inflammatory bowel disease., PMID:38722686
The inositol-requiring enzyme 1 (IRE1) endoplasmic reticulum stress pathway promotes MDA-MB-231 cell survival and renewal in response to the aryl-ureido fatty acid CTU., PMID:38608921
APOE and Alzheimer's disease: Pathologic clues from transgenic Drosophila melanogaster., PMID:38537387
Enhancing Antibody-Specific Productivity: Unraveling the Impact of XBP1s Overexpression and Glutamine Availability in SP2/0 Cells., PMID:38534475
Transcriptomics analysis of LINC02202/XBP1 axis in melanoma: Implications for drug targeting and PD-1 monoclonal antibody efficacy., PMID:38520212
Transcriptomic Analysis Reveals Sixteen Potential Genes Associated with the Successful Differentiation of Antibody-Secreting Cells through the Utilization of Unfolded Protein Response Mechanisms in Robust Responders to the Influenza Vaccine., PMID:38400120
Tumorous IRE1α facilitates CD8+T cells-dependent anti-tumor immunity and improves immunotherapy efficacy in melanoma., PMID:38291473
Platelets induce endoplasmic reticulum stress in macrophages in vitro., PMID:38278417
Loss of function of XBP1 splicing activity of IRE1α favors B cell tolerance breakdown., PMID:38071801
Fibrinogen-like protein 2 promotes tumor immune suppression by regulating cholesterol metabolism in myeloid-derived suppressor cells., PMID:38056898
Rosmarinic acid enhances CHO cell productivity and proliferation through activation of the unfolded protein response and the mTOR pathway., PMID:37897814
Single-cell transcriptome analysis and protein profiling reveal broad immune system activation in IgG4-related disease., PMID:37561593
TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation., PMID:37481835
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells., PMID:37329685
The human bone marrow plasma cell compartment in rheumatoid arthritis - Clonal relationships and anti-citrulline autoantibody producing cells., PMID:37001434
Ezh2 Knockout in B Cells Impairs Plasmablast Differentiation and Ameliorates Lupus-like Disease in MRL/lpr Mice., PMID:36897808
Inhibition of pathologic immunoglobulin E in food allergy by EBF-2 and active compound berberine associated with immunometabolism regulation., PMID:36825019
A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation., PMID:36685499
XBP1-elicited environment by chemotherapy potentiates repopulation of tongue cancer cells by enhancing miR-22/lncRNA/KAT6B-dependent NF-κB signalling., PMID:36639835
The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells., PMID:36618345
Deficiency of p53 Causes the Inadequate Expression of miR-1246 in B Cells of Systemic Lupus Erythematosus., PMID:36165173
Regulatory network of BLIMP1, IRF4, and XBP1 triad in plasmacytic differentiation and multiple myeloma pathogenesis., PMID:36081178
Peripheral CD23hi/IgE+ Plasmablasts Secrete IgE and Correlate with Allergic Disease Severity., PMID:35896336
Endoplasmic reticulum-stress and unfolded protein response-activation in immune-mediated necrotizing myopathy., PMID:35703068
Romidepsin (FK228) improves the survival of allogeneic skin grafts through downregulating the production of donor-specific antibody via suppressing the IRE1α-XBP1 pathway., PMID:35557040
Plasmablast-like Phenotype Among Antigen-Experienced CXCR5-CD19low B Cells in Systemic Lupus Erythematosus., PMID:35507291
FK506-Binding Protein 11 Is a Novel Plasma Cell-Specific Antibody Folding Catalyst with Increased Expression in Idiopathic Pulmonary Fibrosis., PMID:35456020
Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine., PMID:35149556
Macrophage-Derived Immunoglobulin M Inhibits Inflammatory Responses via Modulating Endoplasmic Reticulum Stress., PMID:34831038
Tumor innervation is triggered by endoplasmic reticulum stress., PMID:34785777
Single-cell transcriptome profiling and the use of AID deficient mice reveal that B cell activation combined with antibody class switch recombination and somatic hypermutation do not benefit the control of experimental trypanosomosis., PMID:34762705
Modulation of the Physical Properties of 3D Spheroids Derived from Human Scleral Stroma Fibroblasts (HSSFs) with Different Axial Lengths Obtained from Surgical Patients., PMID:34698138
Collagen XV Promotes ER Stress-Induced Inflammation through Activating Integrin β1/FAK Signaling Pathway and M1 Macrophage Polarization in Adipose Tissue., PMID:34576160
Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer., PMID:34493732
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy., PMID:34414762
Targeting LAG3/GAL-3 to overcome immunosuppression and enhance anti-tumor immune responses in multiple myeloma., PMID:34290359
The Immunity-malignancy equilibrium in multiple myeloma: lessons from oncogenic events in plasma cells., PMID:34117720
For research use only. Not for human or drug use.
