Catalog No.
RHD23302
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
JUNB, Transcription factor jun-B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P17275
Applications
IF, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1Q37
Single-cell transcriptomic analysis reveals AP-1 downregulation remodels bone marrow environment and contributes to osteopenia in ovariectomized mice., PMID:40213116
Humanizing a CD28 signaling domain affects CD8 activation, exhaustion and stem-like precursors., PMID:40161835
Inhibitors of oncogenic Kras specifically prime CTLA4 blockade to transcriptionally reprogram Tregs and overcome resistance to suppress pancreas cancer., PMID:40093186
Progressively differentiated TFH13 cells are stabilized by JunB to mediate allergen germinal center responses., PMID:39891019
Fluorescence-activated nuclear sorting (FANS) of nuclei from in vitro-generated syncytiotrophoblast., PMID:38944560
Transcriptome Analysis Reveals the Induction of Apoptosis-Related Genes by a Monoclonal Antibody against a New Epitope of CD99 on T-Acute Lymphoblastic Leukemia., PMID:38804310
Regulation of Axon Guidance by Slit2 and Netrin-1 Signaling in the Lacrimal Gland of Aqp5 Knockout Mice., PMID:37707834
An innovative immunotherapeutic strategy for rheumatoid arthritis: Selectively suppressing angiogenesis and osteoclast differentiation by fully human antibody targeting thymocyte antigen-1., PMID:36706943
Identification of a distal RXFP1 gene enhancer with differential activity in fibrotic lung fibroblasts involving AP-1., PMID:34972106
Target protein deglycosylation in living cells by a nanobody-fused split O-GlcNAcase., PMID:33686291
NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis., PMID:32956405
Clinical Management and Therapeutic Strategies for the Thyroid-Associated Ophthalmopathy: Current and Future Perspectives., PMID:32567373
CXCR4 and JUNB double-positive disseminated tumor cells are detected frequently in breast cancer patients at primary diagnosis., PMID:32426042
Engineering a Proximity-Directed O-GlcNAc Transferase for Selective Protein O-GlcNAcylation in Cells., PMID:32119511
Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease., PMID:31934626
Cutaneous Immune Cell-Microbiota Interactions Are Controlled by Epidermal JunB/AP-1., PMID:31644908
The prognostic value of JUNB-positive CTCs in metastatic breast cancer: from bioinformatics to phenotypic characterization., PMID:31370904
JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling., PMID:31285535
AP-1cFos/JunB/miR-200a regulate the pro-regenerative glial cell response during axolotl spinal cord regeneration., PMID:30854483
Multiplex quantitative imaging of human myocardial infarction by mass spectrometry-immunohistochemistry., PMID:29556718
Increased mTOR cancels out the effect of reduced Xbp-1 on antibody secretion in IL-1α-deficient B cells., PMID:29499909
CCL2 as a potential therapeutic target for clear cell renal cell carcinoma., PMID:27666332
Early markers for myocardial ischemia and sudden cardiac death., PMID:27392959
Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse model., PMID:27340921
Interleukin-6 receptor alpha blockade improves skin lesions in a murine model of systemic lupus erythematosus., PMID:26739431
Preclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 Transgene., PMID:26076730
Specific roles for dendritic cell subsets during initiation and progression of psoriasis., PMID:25216727
The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma., PMID:25145835
Induction of ATF3 gene network by triglyceride-rich lipoprotein lipolysis products increases vascular apoptosis and inflammation., PMID:23868936
Transcriptional regulation of PES1 expression by c-Jun in colon cancer., PMID:22860098
Suppression of AP1 transcription factor function in keratinocyte suppresses differentiation., PMID:22649503
JunB promotes cell invasion and angiogenesis in VHL-defective renal cell carcinoma., PMID:22020339
Angiopoietin-like 4 regulates epidermal differentiation., PMID:21966511
Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1., PMID:21809421
Dimethylfumarate inhibits MIF-induced proliferation of keratinocytes by inhibiting MSK1 and RSK1 activation and by inducing nuclear p-c-Jun (S63) and p-p53 (S15) expression., PMID:21340650
The transcription factor B-cell lymphoma (BCL)-6 modulates pancreatic {beta}-cell inflammatory responses., PMID:21190961
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma., PMID:20926789
An NF-kappaB-dependent role for JunB in the induction of proinflammatory cytokines in LPS-activated bone marrow-derived dendritic cells., PMID:20221401
Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis., PMID:19995970
Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling., PMID:19918056
Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-gamma stimulated macrophages., PMID:19893639
Utility of fascin and JunB in distinguishing nodular lymphocyte predominant from classical lymphocyte-rich Hodgkin lymphoma., PMID:19550297
Viperin is required for optimal Th2 responses and T-cell receptor-mediated activation of NF-kappaB and AP-1., PMID:19047684
Abnormal AP-1 protein expression in primary cutaneous B-cell lymphomas., PMID:18460027
Genes overexpressed in cerebral arteries following salt-induced hypertensive disease are regulated by angiotensin II, JunB, and CREB., PMID:18156195
B-cell receptor activation induces BIC/miR-155 expression through a conserved AP-1 element., PMID:18048365
JunB is required for IgE-mediated degranulation and cytokine release of mast cells., PMID:17982078
Abnormal activator protein 1 transcription factor expression in CD30-positive cutaneous large-cell lymphomas., PMID:17725669
The mitogen-activated protein kinase p38 regulates activator protein 1 by direct phosphorylation of c-Jun., PMID:17689131
A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells., PMID:17439946
For research use only. Not for human or drug use.
