Catalog No.
RHC85801
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
EGR-2, E3 SUMO-protein transferase ERG2, E3 SUMO-protein ligase EGR2, EGR2, Zinc finger protein Krox-20, AT591, Early growth response protein 2, KROX20
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P11161
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1N25
Memory Phenotype Tfh Cells Develop Without Overt Infection and Support Germinal Center Formation and B Cell Responses to Viral Infection., PMID:39568245
Exploration of the shared gene signatures and biological mechanisms between ischemia-reperfusion injury and antibody-mediated rejection in renal transplantation., PMID:38266883
Characterization of microglia/macrophage phenotypes in the spinal cord following intervertebral disc herniation., PMID:36262531
EGR2 Deletion Suppresses Anti-DsDNA Autoantibody and IL-17 Production in Autoimmune-Prone B6/lpr Mice: A Differential Immune Regulatory Role of EGR2 in B6/lpr Versus Normal B6 Mice., PMID:35784356
Deficiency in the frequency and function of Tr1 cells in IgAV and the possible role of IL-27., PMID:33280050
Oct-6 transcriptional factor a possible biomarker for leprosy diagnosis., PMID:33130505
Aggregates of IVIG or Avastin, but not HSA, modify the response to model innate immune response modulating impurities., PMID:30065306
Novel Richter Syndrome Xenograft Models to Study Genetic Architecture, Biology, and Therapy Responses., PMID:29735551
NAD metabolism fuels human and mouse intestinal inflammation., PMID:28877980
Identification of zinc finger transcription factor EGR2 as a novel acetylated protein., PMID:28576496
Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis., PMID:28511719
Transcriptional Heterogeneity of Mast Cells and Basophils upon Activation., PMID:28476932
A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity., PMID:28228602
The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment., PMID:28115575
Expression of Egr3 in mouse gonads and its localization and function in oocytes., PMID:28002932
Functional Role of γ-Crystallin N in the Auditory Hindbrain., PMID:27517863
Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins., PMID:26678612
Early Growth Response Genes 2 and 3 Regulate the Expression of Bcl6 and Differentiation of T Follicular Helper Cells., PMID:25979336
[Regulatory T cells in systemic lupus erythematosus]., PMID:25765691
TGF-β3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses., PMID:25695838
Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25., PMID:25582080
Dysregulation of anergy-related factors involved in regulatory T cells defects in Systemic Lupus Erythematosus patients: Rapamycin and Vitamin D efficacy in restoring regulatory T cells., PMID:25351606
TCR stimulation without co-stimulatory signals induces expression of "tolerogenic" genes in memory CD4 T cells but does not compromise cell proliferation., PMID:25306961
Effects of an oxycodone conjugate vaccine on oxycodone self-administration and oxycodone-induced brain gene expression in rats., PMID:25025380
Acquired initiating mutations in early hematopoietic cells of CLL patients., PMID:24920063
Expression and effects of epidermal growth factor on human periodontal ligament cells., PMID:24850273
A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes., PMID:23355739
CD40 activation induces NREM sleep and modulates genes associated with sleep homeostasis., PMID:23072727
Characterization of proliferative effects of insulin, insulin analogues and insulin-like growth factor-1 (IGF-1) in human lung fibroblasts., PMID:20924562
Cellular immediate-early gene expression occurs kinetically upstream of Epstein-Barr virus bzlf1 and brlf1 following cross-linking of the B cell antigen receptor in the Akata Burkitt lymphoma cell line., PMID:20861250
Regulation of peripheral myelination by Src-like kinases., PMID:20696161
Embryonic corneal Schwann cells express some Schwann cell marker mRNAs, but no mature Schwann cell marker proteins., PMID:19387082
Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease., PMID:18779345
Reconstitution of Schwannian stroma in neuroblastomas using human bone marrow stromal cells., PMID:18772334
A peptide that ameliorates lupus up-regulates the diminished expression of early growth response factors 2 and 3., PMID:18209054
Differential regulation of NAB corepressor genes in Schwann cells., PMID:18096076
Glucocorticoids inhibit osteocalcin transcription in osteoblasts by suppressing Egr2/Krox20-binding enhancer., PMID:15751078
Functional role of a novel ternary complex comprising SRF and CREB in expression of Krox-20 in early embryos of Xenopus laevis., PMID:15617690
Relationship between hindbrain segmentation, neural crest cell migration and branchial arch abnormalities in rat embryos exposed to fluconazole and retinoic acid in vitro., PMID:15013071
The ontogeny of Krox-20 expression in brainstem and cerebellar neurons., PMID:12706208
Altered gene expression upon BCR cross-linking in Burkitt's lymphoma B cell line., PMID:11027651
Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms' tumor suppressor protein., PMID:9627060
Expression of Fos, Jun, and Krox family proteins in Alzheimer's disease., PMID:9344557
Oct-1, silencer sequence, and GC box regulate thyroid hormone receptor beta1 promoter., PMID:9220031
Expression of Krox proteins during differentiation of the O-2A progenitor cell line CG-4., PMID:9109517
Induction of the early growth response (Egr) family of transcription factors during thymic selection., PMID:9034151
Oct-6 (SCIP/Tst-1) is expressed in Schwann cell precursors, embryonic Schwann cells, and postnatal myelinating Schwann cells: comparison with Oct-1, Krox-20, and Pax-3., PMID:8951674
Role of EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes., PMID:8628295
B cell early response gene expression coupled to B cell receptor, CD40 and interleukin-4 receptor co-stimulation: evidence for a role of the egr-2/krox 20 transcription factor in B cell proliferation., PMID:8625972
Molecular cloning of a novel human cDNA encoding a zinc finger protein that binds to the interleukin-3 promoter., PMID:8035792