Catalog No.
RHC69302
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
HSP70.1, HSP70-1, HSPA1, HSPA1A, Heat shock 70 kDa protein 1A, Heat shock 70 kDa protein 1, HSP72, HSX70
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P0DMV8, P0DMV9
Applications
FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1M49
Cannabidiol ameliorates seizures and neuronal damage in ferric chloride-induced posttraumatic epilepsy by targeting TRPV1 channel., PMID:40449694
Hsc70-4: An unanticipated mediator of dsRNA internalization in Drosophila., PMID:40378201
[Efficient capture and proteomics analysis of urinary extracellular vesicles by affinity purification]., PMID:40331614
Differential Induction of Endoplasmic Reticulum Stress Signaling by Antibody Isotypes: Implications for Plasma Cell Differentiation., PMID:40285383
LGALS3BP antibody-drug conjugate enhances tumor-infiltrating lymphocytes and synergizes with immunotherapy to restrain neuroblastoma growth., PMID:40217513
GRP78 Nanobody-Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy., PMID:40135833
Profiling Nascent Tumor Extracellular Vesicles via Metabolic Timestamping and Aptamer-Driven Specific Click Chemistry., PMID:40082216
A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response., PMID:40073153
Expanding the fluorescent toolkit: Blue fluorescent protein-expressing Plasmodium berghei for enhanced multiplex microscopy., PMID:40029851
Celastrol-loaded ginsenoside Rg3 liposomes enhance anti-programmed death ligand 1 immunotherapy by inducing immunogenic cell death in triple-negative breast cancer., PMID:39986227
TLR2-Bound Cancer-Secreted Hsp70 Induces MerTK-Mediated Immunosuppression and Tumorigenesis in Solid Tumors., PMID:39941817
Functional epitope mapping of cell surface glucose-regulated protein 94: A combinatorial approach for therapeutic targeting., PMID:39880265
Recombinant antibodies inhibit enzymatic activity of the E3 ubiquitin ligase CHIP via multiple mechanisms., PMID:39863102
Integrating immunity, antioxidative status, and gene regulation against nickel and high-temperature stress in fish: selenium nanoparticles for mitigation., PMID:39843820
Extracellular HSP70 facilitated β-glucan induced trained immunity in macrophages to suppress sepsis via TLR2-NF-κB axis., PMID:39823994
Investigating the Process of Autoimmune Inner Ear Disease: Unveiling the Intricacies of Pathogenesis and Therapeutic Strategies., PMID:39744176
Hspa13 Deficiency Impaired Marginal Zone B Cells Regulatory Function and Contributed to Lupus Pathogenesis., PMID:39737854
Design and Cytotoxicity Evaluation of a Cancer-targeting Immunotoxin Based on a Camelid Nanobody-PE Fusion Protein., PMID:39731471
aPKC/Par3/Par6 polarity complexes regulate podocyte motility and crescent formation in the progression of ANCA-associated vasculitis., PMID:39700430
The isolation of VCAM-1+ endothelial cell-derived extracellular vesicles using microfluidics., PMID:39698414
Exosomes derived from TREM-2 knocked-out macrophages alleviated renal fibrosis via HSPa1b/AKT pathway., PMID:39657110
Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo., PMID:39605463
The Spleen Modulates the Balance of Natural and Pathological Autoantibodies in a Mouse Model of Autoimmune Arthritis., PMID:39519235
Extracellular Hsp70 and Circulating Endometriotic Cells as Novel Biomarkers for Endometriosis., PMID:39519195
Optimising Growth, Immunity, and Gene Expression in Broiler Chickens Through Dietary Threonine Levels and Oil Inclusion., PMID:39501595
Epigallocatechin-3-gallate induces immunogenic cell death and enhances cancer immunotherapy in colorectal cancer., PMID:39471680
Synthetic and Natural Inhibitors of Mortalin for Cancer Therapy., PMID:39456564
Analysis of virulence factors in extracellular vesicles secreted by Naegleria fowleri., PMID:39432113
Dendritic Cells Loaded With Heat Shock Inactivated Glioma Stem Cells Enhance Antitumor Response of Mouse Glioma When Combining With CD47 Blockade., PMID:39429684
Proteomic identification of allergenic proteins in holm oak (Quercus ilex) seeds., PMID:39426264
Blood-Brain Barrier Disruption in Neuroimmunological Disease., PMID:39408955
Improved ex vivo fluorescence imaging of human head and neck cancer using the peptide tracer TPP-IRDye800 targeting membrane-bound Hsp70 on tumor cells., PMID:39406917
In silico and in vitro evaluation of a PE38 and Nb-based recombinant immunotoxin targeting the GRP78 receptor in cancer cells., PMID:39397264
O-GlcNAcylation of ribosome-associated proteins is concomitant with translational reprogramming during proteotoxic stress., PMID:39395807
Avian malaria in a feral-pet pigeon: a case report., PMID:39358742
Investigating the immunological activity of the Hsp70-P113 fusion protein for Mycoplasma ovipneumoniae detection: a groundbreaking study., PMID:39304865
Anti-Heat Shock Protein 70 Autoantibodies from Patients with Idiopathic Pulmonary Fibrosis Epigenetically Enhance Lung Fibroblast Apoptosis Resistance and Bcl-2 Expression., PMID:39248593
Alterations in immunized antigens of Anisakis pegreffii by ampicillin-induced gut microbiome changes in mice., PMID:39218634
Disclosing the Novel Protective Mechanisms of Ocrelizumab in Multiple Sclerosis: The Role of PKC Beta and Its Down-Stream Targets., PMID:39201609
A longitudinal assessment of heat exposure and biomarkers of kidney function on heat shock protein 70 and antibodies among agricultural workers., PMID:39198762
A novel bispecific T-cell engager using the ligand-target csGRP78 against acute myeloid leukemia., PMID:39196413
Detection of autoantibodies to heat shock protein 70 in the saliva and urine of normal individuals., PMID:39136018
CD5L up-regulates the TGF-β signaling pathway and promotes renal fibrosis., PMID:39127319
UGT1A7 altered HER2-positive breast cancer response to trastuzumab by affecting epithelial-to-mesenchymal transition: A potential biomarker to identify patients resistant to trastuzumab treatment., PMID:39122832
Analysis of Co-expression of HSP 70 and BCL 2 in Oral Precancer and Cancer Patients Using Immunohistochemistry., PMID:39118904
Small molecules targeting GRP78 mitigate anti-GRP78 autoantibody-mediated tissue factor procoagulant activity in cultured endothelial cells., PMID:39111636
Biomimetic nanocomplex based corneal neovascularization theranostics., PMID:39111599
Alleviating effect of methionine on intestinal mucosal injury induced by heat stress., PMID:39098059
Cobalt(III) prodrug-based nanomedicine for inducing immunogenic cell death and enhancing chemo-immunotherapy., PMID:39033985
Immunoexpression Pattern of Autophagy-Related Proteins in Human Congenital Anomalies of the Kidney and Urinary Tract., PMID:38999938
For research use only. Not for human or drug use.
