Catalog No.
YHC30901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp35-Gly285
Predicted molecular weight
30.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08174
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Complement decay-accelerating factor, CR, DAF, CD55
Human CD55 Expression and C1 Inhibition Partially Protect Gene-Edited Pig Red Blood Cells From Human Complement-Mediated Hemolysis In Vitro., PMID:40492338
Therapeutic targets for Alzheimer's disease: Proteome-wide Mendelian randomization and colocalization analyses., PMID:40452368
Natural killer cells adopt an activated and decidual-like phenotype after autologous hematopoietic stem cell transplantation in children with cancer., PMID:40437214
The decay-accelerating factor (CD55) in acute leukemia patients and its query implication in cancer pathogenesis., PMID:40419851
Evidence for Complement Activation in Preeclampsia Placenta and Its Presence in Circulation., PMID:40388260
CD55 upregulation in T cells of COVID-19 patients suppresses type-I interferon responses., PMID:40316776
Complement dysregulation at lymphatics., PMID:40300720
Mechanism and regulation of the complement activity in kidney xenotransplantation., PMID:40233672
Minimally invasive retrieval and characterisation of tenosynovial tissue in rheumatoid arthritis: a novel approach to study at-risk, active, and remission stages., PMID:40148202
Bioinformatic analysis of serpina1 expression in papillary thyroid carcinoma and its potential association with Hashimoto's thyroiditis., PMID:40106166
Stromal Cell Subsets Show Model-Dependent Changes in Experimental Colitis and Affect Epithelial Tissue Repair and Immune Cell Activation., PMID:40100003
Claudin-2 enhances human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells by modulating antibody binding and complement activation., PMID:40040710
Complement activity and autophagy are dysregulated in the lungs of patients with nonresolvable COVID-19 requiring lung transplantation., PMID:40016722
Evaluation of Complement-Dependent Cytotoxicity Assays for Gene-Edited Pig-to-Human Xenotransplantation., PMID:39960350
Gene expression regulation and polyadenylation in ulcerative colitis via long-chain RNA sequencing., PMID:39955510
SARS-CoV-2 enhances complement-mediated endothelial injury via the suppression of membrane complement regulatory proteins., PMID:39945674
Establishment of a Panel of Human Cell Lines to Identify Cellular Receptors Used by Enteroviruses to Infect Cells., PMID:39940693
Neutrophil-derived vesicles control complement activation to facilitate inflammation resolution., PMID:39938514
The patient experience of CHAPLE disease: results from interviews conducted as part of a clinical trial for an ultra-rare condition., PMID:39934837
Discovery of a second, distinct development pattern of leukemic conversion from paroxysmal nocturnal hemoglobinuria., PMID:39910008
Mitochondrial injury and complement dysregulation are drivers of pathological inflammation in viral myocarditis., PMID:39846741
Complement regulators as novel targets for anti-cancer therapy: A comprehensive review., PMID:39826189
Evaluation of Complement-Dependent Cytotoxicity Assays for Gene-Edited Pig-to-Human Xenotransplantation., PMID:39825616
Exosome-Mediated Lectin Pathway and Resistin-MIF-AA Metabolism Axis Drive Immune Dysfunction in Immune Thrombocytopenia., PMID:39792656
SNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression., PMID:39704173
EBV-induced upregulation of CD55 reduces the efficacy of cetuximab treatment in nasopharyngeal carcinoma., PMID:39695702
A large-scale proteomics resource of circulating extracellular vesicles for biomarker discovery in pancreatic cancer., PMID:39693144
An evaluation of pozelimab for the treatment of CHAPLE disease., PMID:39657032
CD55 characterizes regulatory T cells with reduced functionality and is downregulated in rheumatoid arthritis., PMID:39657534
Deciphering proteins in Alzheimer's disease: A new Mendelian randomization method integrated with AlphaFold3 for 3D structure prediction., PMID:39637861
Generation and characterization of genetically modified pigs with GGTA1/β4GalNT2/CMAH knockout and human CD55/CD47 expression for xenotransfusion studies., PMID:39622959
Essential role of Moringa-albumin (MA) formulation in the maintenance of complement regulatory proteins on erythrocyte (TER-119) cells in diabetic mouse models., PMID:39526711
Clinical Significance of Complement and Coagulation Cascades Genes for Patients With Acute Lymphoblastic Leukemia., PMID:39523585
SARS-CoV-2 hijacks host CD55, CD59 and factor H to impair antibody-dependent complement-mediated lysis., PMID:39435487
RBC subpopulations in RCCs affected by donor factors., PMID:39426025
CD151 identifies an NK cell subset that is enriched in COVID-19 patients and correlates with disease severity., PMID:39374860
N-glycoproteomic and proteomic alterations in SRD5A3-deficient fibroblasts., PMID:39360848
Complement biosensors identify a classical pathway stimulus in complement-mediated thrombotic microangiopathy., PMID:39357054
[The rs2564978(T) Allele Associated with Severe Influenza A Disrupts the Binding Site for Myeloid Differentiation Factor PU.1 and Reduces CD55/DAF Gene Promoter Activity in Macrophages]., PMID:39355884
Population pharmacokinetic analyses of pozelimab in patients with CD55-deficient protein-losing enteropathy (CHAPLE disease)., PMID:39349796
Exercise training upregulates CD55 to suppress complement-mediated synaptic phagocytosis in Parkinson's disease., PMID:39342308
A Histological Analysis and Detection of Complement Regulatory Protein CD55 in SARS-CoV-2 Infected Lungs., PMID:39337843
Complement-Mediated Two-Step NETosis: Serum-Induced Complement Activation and Calcium Influx Generate NADPH Oxidase-Dependent NETs in Serum-Free Conditions., PMID:39273570
Navigating the Complement Pathway to Optimize PNH Treatment with Pegcetacoplan and Other Currently Approved Complement Inhibitors., PMID:39273426
Single-cell RNA sequencing identifies inherent abnormalities of adipose-derived stem cells from nonlesional sites of patients with localized scleroderma., PMID:39215271
Erythropoietin Effect on Complement Activation in Chronic Kidney Disease., PMID:39200211
Iscalimab Combined With Transient Tesidolumab Prolongs Survival in Pig-to-Rhesus Monkey Renal Xenografts., PMID:39185772
NETWORK ANALYSIS OF SINGLE-NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH ABERRANT INFLAMMATION IN TRAUMA PATIENTS SUGGESTS A ROLE FOR VESICLE-ASSOCIATED INFLAMMATORY PROGRAMS INVOLVING CD55., PMID:39178207
Senescence-related genes and proteins in the development of Alzheimer's disease: evidence from transcriptomic and Mendelian randomization analysis., PMID:39156738
Pozelimab for CHAPLE disease: results from in-trial interviews and clinical outcome assessments., PMID:39118150
For research use only. Not for human or drug use.
