Catalog No.
YHC30501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys29-Asn250
Predicted molecular weight
25.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08138
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Low affinity neurotrophin receptor p75NTR, TNFRSF16, CD271, Gp80-LNGFR, p75 ICD, Low-affinity nerve growth factor receptor, NGFR, NGF receptor, Tumor necrosis factor receptor superfamily member 16
Transcriptional evidence of reduced BDNF trophic capacity in the post-mortem human midbrain of schizophrenia cases with high inflammation., PMID:40335479
Dysregulation of proBDNF/p75NTR and BDNF/TrkB Signaling in Acute Ischemic Stroke: Different Sides of the Same Coins., PMID:40209946
Injectable Functional Microspheres Capable of BMSC Recruitment and Osteogenic Induction for In Situ Bone Regeneration., PMID:40131171
CD271 Serves as a Marker for Tumor-Initiating Cells in Laryngocarcinoma., PMID:40116102
Dual role of interferon-gamma in the response of melanoma patients to immunotherapy with immune checkpoint inhibitors., PMID:40108693
Oxidative Stress Suppresses Trk Signaling While Stimulating JNK-Mediated Endocytosis and Cleavage of p75NTR: A Targetable Pathway for Neuroprotection in a Parkinson's Disease Model., PMID:39936238
Heterotypic interactions among members of the death domain superfamily with implications for p75NTR-mediated co-signaling., PMID:39924025
Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration., PMID:39863771
CD271high cancer stem cells regulate macrophage polarization in head and neck squamous cell carcinoma., PMID:39854870
CD271 regulates osteogenic differentiation of ectomesenchymal stem cells via the RhoA/ROCK signaling pathway., PMID:39826451
CD9/SOX2-positive cells in the intermediate lobe of the rat pituitary gland exhibit mesenchymal stem cell characteristics., PMID:39808267
Resveratrol Can Differentiate Human Melanoma Stem-like Cells from Spheroids Treated With All-trans Retinoic Acid., PMID:39626925
Synthesis, characterisation, and anti-tumour activity of nano-immuno-conjugates for enhanced photodynamic therapy of oesophageal cancer stem cells., PMID:39550831
Pulse Activation of Retinoic Acid Receptor Enhances Hematopoietic Stem Cell Homing by Controlling CXCR4 Membrane Presentation., PMID:39480614
The influence of fetal bovine serum concentration on stemness and neuronal differentiation markers in stem cells from human exfoliated deciduous teeth., PMID:39353229
Alcohol use disorder disrupts BDNF maturation via the PAI-1 pathway which could be reversible with abstinence., PMID:39333668
Efficient and cost-effective differentiation of induced neural crest cells from induced pluripotent stem cells using laminin 211., PMID:39290629
Adipocyte-secreted PRELP promotes adipocyte differentiation and adipose tissue fibrosis by binding with p75NTR to activate FAK/MAPK signaling., PMID:39244119
Brain plasticity and neuroinflammatory protein biomarkers with circulating MicroRNAs as predictors of acute brain injury outcome - A prospective cohort study., PMID:39126731
LM11A-31, a modulator of p75 neurotrophin receptor, suppresses HIV-1 replication and inflammatory response in macrophages., PMID:39119118
SNORD88B-mediated WRN nucleolar trafficking drives self-renewal in liver cancer initiating cells and hepatocarcinogenesis., PMID:39112443
Widespread Distribution of Luteinizing Hormone/Choriogonadotropin Receptor in Human Juvenile Angiofibroma: Implications for a Sex-Specific Nasal Tumor., PMID:39056799
Induction of periodontal ligament-derived mesenchymal stromal cell-like cells from human induced pluripotent stem cells., PMID:39045575
PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients., PMID:38978350
Identification of cellular and noncellular components of mature intact human peripheral nerve., PMID:38973168
Extracellular matrices of stromal cell subtypes regulate phenotype and contribute to the stromal microenvironment in vivo., PMID:38886845
Cytokeratin 17 expression is commonly observed in keratinocytic skin tumours and controls tissue homeostasis impacting human papillomavirus protein expression., PMID:38878280
Cooperative interactions between neurotrophin receptors and CXCR4 regulate macrophage phenotype and susceptibility to activation by HIV., PMID:38822196
p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trial., PMID:38760589
Ethnicity-Based Variations in Focal Adhesion Kinase Signaling in Glioblastoma Gene Expression: A Study of the Puerto Rican Hispanic Population., PMID:38732165
CSChighE-cadherinlow immunohistochemistry panel predicts poor prognosis in oral squamous cell carcinoma., PMID:38719848
CD271 mRNA/hnRNPA2B1 complex promotes proliferation and stemness in oral and head and neck squamous cell carcinoma., PMID:38710200
Role of basal cells in nasal polyp epithelium in the pathophysiology of eosinophilic chronic rhinosinusitis (eCRS)., PMID:38670810
P75NTR+CD64+ neutrophils promote sepsis-induced acute lung injury., PMID:38599263
[Different concentrations of adapalene induce differentiation and apoptosis of SH-SY5Y cells]., PMID:38557381
Intranasal delivery of small extracellular vesicles from specific subpopulation of mesenchymal stem cells mitigates traumatic spinal cord injury., PMID:38519036
Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells., PMID:38428412
Mechanism of action of adapalene for treating EGFR-TKI-induced skin disorder., PMID:38379420
A positive feedback between PDIA3P1 and OCT4 promotes the cancer stem cell properties of esophageal squamous cell carcinoma., PMID:38254118
Heterogeneity-induced NGF-NGFR communication inefficiency promotes mitotic spindle disorganization in exhausted T cells through PREX1 suppression to impair the anti-tumor immunotherapy with PD-1 mAb in hepatocellular carcinoma., PMID:38204220
Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway in mucosal melanoma fitness., PMID:38191367
ISX-9 Promotes KGF Secretion From MSCs to Alleviate ALI Through NGFR-ERK-TAU-β-Catenin Signaling Axis., PMID:38159248
Targeting AR-positive breast cancer cells via drug repurposing approach., PMID:38157661
Toward a human brain extracellular vesicle atlas: Characteristics of extracellular vesicles from different brain regions, including small RNA and protein profiles., PMID:38089920
CD271 promotes proliferation and migration in bladder cancer., PMID:38016691
Feline SCCs of the Head and Neck Display Partial Epithelial-Mesenchymal Transition and Harbor Stem Cell-like Cancer Cells., PMID:38003753
Expression profiles of human somatic mesenchymal stem cells derived from fresh endometrium, ectopic-endometrium and umbilical cord., PMID:37934895
Putative Cancer Stem Cell Markers are Frequently Expressed by Melanoma Cells in Vitro and in Situ but are also Present in Benign Differentiated Cells., PMID:37796710
Targeted Delivery of RGD-CD146+CD271+ Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Promotes Blood-Spinal Cord Barrier Repair after Spinal Cord Injury., PMID:37695238
AbobotulinumtoxinA improves skin properties and sebum quality in the rhino mouse., PMID:37517594
For research use only. Not for human or drug use.
