Catalog No.
YHC30301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Ser251
Predicted molecular weight
30.44 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08133
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% SKL, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Chromobindin-20, ANX6, ANXA6, Annexin A6, CPB-II, p70, Protein III, Lipocortin VI, 67 kDa calelectrin, Calphobindin-II, p68, Annexin-6, Annexin VI
Application of RNA-seq for single nucleotide variation identification in a cohort of patients with hypertrophic cardiomyopathy., PMID:40442228
Enterohemorrhagic Escherichia coli O157:H7 Infection Inhibits Host Endoplasmic Reticulum Stress in Intestinal Epithelial Cells via the PERK Pathway., PMID:40430759
Small Extracellular Vesicles Orchestrate Cisplatin-Induced Ototoxicity: Potential Biomarker and Targets Discovery., PMID:40411396
[Ursolic acid down-regulates ANXA6 and inhibits breast cancer cell growth and metastasis]., PMID:40374359
Identification of host factors affecting Chicken Infectious Anemia Virus infection and pathogenicity through RNA-seq and LC-MS., PMID:40279723
Neuroinflammation mediates the progression of neonate hypoxia-ischemia brain damage to Alzheimer's disease: a bioinformatics and experimental study., PMID:39872979
Preclinical Efficacy and Proteomic Prediction of Molecular Targets for s-cal14.1b and s-cal14.2b Conotoxins with Antitumor Capacity in Xenografts of Malignant Pleural Mesothelioma., PMID:39852534
Calcium phosphate formation and deposition in ischemic neurons., PMID:39820937
ANXA6 expression as a potential indicator of tumor diagnosis, metastasis and immunity in nasopharyngeal carcinoma., PMID:39577524
Transcription factor PRRX1-activated ANXA6 facilitates EGFR-PKCα complex formation and enhances cisplatin sensitivity in bladder cancer., PMID:39528080
Oxalate-upregulated annexin A6 promotes the formation of calcium oxalate kidney stones by exacerbating calcium release-mediated oxidative stress injury in renal tubular epithelial cells and crystal-cell adhesion., PMID:39490615
Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells., PMID:39484394
Sequential window acquisition of all theoretical mass spectra (SWATH-MS) as an emerging proteomics approach for the discovery of dark-cutting beef biomarkers., PMID:39096797
SUMOylation of annexin A6 retards cell migration and tumor growth by suppressing RHOU/AKT1-involved EMT in hepatocellular carcinoma., PMID:38566133
Bending of a lipid membrane edge by annexin A5 trimers., PMID:38486451
FLIM-FRET-based analysis of S100A11/annexin interactions in living cells., PMID:38408765
Annexin A6 mitigates neurological deficit in ischemia/reperfusion injury by promoting synaptic plasticity., PMID:38380783
Bioinformatics analysis reveals the potential common genes and immune characteristics between atrial fibrillation and periodontitis., PMID:37971162
Surfaceome analysis of extracellular vesicles from senescent cells uncovers uptake repressor DPP4., PMID:37862381
AnnexinA6: a potential therapeutic target gene for extracellular matrix mineralization., PMID:37727505
SUMOylation of AnxA6 facilitates EGFR-PKCα complex formation to suppress epithelial cancer growth., PMID:37528485
Comprehensive analysis the diagnosis, malignant progression and immune infiltrate of ANXA6 in prostate cancer., PMID:37311953
A multidisciplinary functional proteomics-aided strategy as a tool for the profiling of a novel cytotoxic thiadiazolopyrimidone., PMID:37229937
Annexin A6 mediates calcium-dependent exosome secretion during plasma membrane repair., PMID:37204294
Proteomic Portrait of Human Lymphoma Reveals Protein Molecular Fingerprint of Disease Specific Subtypes and Progression., PMID:37197640
ANXA6/TRPV2 axis promotes lymphatic metastasis in head and neck squamous cell carcinoma by inducing autophagy., PMID:37138336
ANXA6: a key molecular player in cancer progression and drug resistance., PMID:37129645
Annexin-A5 and annexin-A6 silencing prevents metastasis of breast cancer cells in zebrafish., PMID:36958013
Identification of tumor antigens and immune landscapes for bladder urothelial carcinoma mRNA vaccine., PMID:36761744
MANF/EWSR1/ANXA6 pathway might as the bridge between hypolipidemia and major depressive disorder., PMID:36585419
Interplay of membrane crosslinking and curvature induction by annexins., PMID:36581673
Natural selection of immune and metabolic genes associated with health in two lowland Bolivian populations., PMID:36574663
Fluid Shear Stress Regulates Osteogenic Differentiation via AnnexinA6-Mediated Autophagy in MC3T3-E1 Cells., PMID:36555344
Annexin A6 Polymorphism Is Associated with Pro-atherogenic Lipid Profiles and with the Downregulation of Methotrexate on Anti-Atherogenic Lipid Profiles in Psoriasis., PMID:36498634
Apigenin Modulates AnxA6- and TNAP-Mediated Osteoblast Mineralization., PMID:36361965
Hypoxia-Inducible Expression of Annexin A6 Enhances the Resistance of Triple-Negative Breast Cancer Cells to EGFR and AR Antagonists., PMID:36230969
EZH2 Regulates ANXA6 Expression via H3K27me3 and Is Involved in Angiotensin II-Induced Vascular Smooth Muscle Cell Senescence., PMID:36160712
Mineralization Profile of Annexin A6-Harbouring Proteoliposomes: Shedding Light on the Role of Annexin A6 on Matrix Vesicle-Mediated Mineralization., PMID:36012211
CD9 mediates the uptake of extracellular vesicles from cancer-associated fibroblasts that promote pancreatic cancer cell aggressiveness., PMID:35917363
A conserved annexin A6-mediated membrane repair mechanism in muscle, heart, and nerve., PMID:35866481
Linking Late Endosomal Cholesterol with Cancer Progression and Anticancer Drug Resistance., PMID:35806209
iTRAQ-based quantitative proteomics reveals biomarkers/pathways in psoriasis that can predict the efficacy of methotrexate., PMID:35666151
Understanding Myoblast Differentiation Pathways When Cultured on Electroactive Scaffolds through Proteomic Analysis., PMID:35635507
The mouse Anxa6/miR-9-5p/Anxa2 axis modulates TGF-β1-induced mouse hepatic stellate cell (mHSC) activation and CCl4-caused liver fibrosis., PMID:35483553
Fluorescence evidence of annexin A6 translocation across membrane in model matrix vesicles during apatite formation., PMID:38939118
Phosphoproteome Analysis Identifies a Synaptotagmin-1-Associated Complex Involved in Ischemic Neuron Injury., PMID:35257887
Extracellular Matrix Derived From Dental Pulp Stem Cells Promotes Mineralization., PMID:35155398
Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions., PMID:35022465
Identification of a genetic signature enriching for response to ibrutinib in relapsed/refractory follicular lymphoma in the DAWN phase 2 trial., PMID:34791836
Breast Cancer Stem Cell-Derived ANXA6-Containing Exosomes Sustain Paclitaxel Resistance and Cancer Aggressiveness in Breast Cancer., PMID:34676207
For research use only. Not for human or drug use.
