Catalog No.
RMC20501
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000
Target
Protein S100-A9, CAGB, MRP-14, S100 calcium-binding protein A9, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, p14, Calprotectin L1H subunit, S100A9, Calgranulin-B, CFAG, MRP14
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P31725
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1K70
Synergistic inhibition of CitH3 and S100A8/A9: A novel therapeutic strategy for mitigating sepsis-induced inflammation and lung injury., PMID:40390290
Identification of S100A9 as a target for diagnosis and treatment of Crohn's Disease after Vedolizumab treatment failure., PMID:40280281
[The effects of S100A9 gene knockout on lupus-like phenotype in mice]., PMID:40260564
Extracellular vesicle-bound S100A8/A9 is differentially expressed in septic shock and prompts acute lung injury., PMID:40102943
Targeting S100A8/A9-NCF1 axis in tumor microenvironment to prevent tumor metastasis by self-assembled peptide nanofibers., PMID:40040282
E-twenty-six-specific sequence variant 5 (ETV5) facilitates hepatocellular carcinoma progression and metastasis through enhancing polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC)-mediated immunosuppression., PMID:40015948
An S100A8/A9 Neutralizing Antibody Potently Ameliorates Contact Hypersensitivity and Atopic Dermatitis Symptoms., PMID:39848567
A pan-immune panorama of bacterial pneumonia revealed by a large-scale single-cell transcriptome atlas., PMID:39757231
Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR-mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis., PMID:39715697
Intraperitoneal Administration of S100A8 Ameliorates Experimental Acute Colitis in Rats., PMID:39596871
Neutrophil-secreted S100A8/A9 participates in fatty liver injury and fibrosis by promoting myofibroblast migration., PMID:38995368
VNN2-expressing circulating monocytes exhibit unique functional characteristics and are decreased in patients with primary Sjögren's syndrome., PMID:38936146
S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis., PMID:38918871
Development of protein-polymer conjugate nanoparticles for modulation of dendritic cell phenotype and antigen-specific CD4 T cell responses., PMID:38911349
S100a8/9 (S100 Calcium Binding Protein a8/9) Promotes Cardiac Hypertrophy Via Upregulation of FGF23 (Fibroblast Growth Factor 23) in Mice., PMID:38726894
Targeting IL-13 with tralokinumab normalizes type 2 inflammation in atopic dermatitis both early and at 2 years., PMID:38563683
Plasma sCD146 is a potential biomarker for acute exacerbation of chronic obstructive pulmonary disease., PMID:38476031
Longitudinal plasma proteome profiling reveals the diversity of biomarkers for diagnosis and cetuximab therapy response of colorectal cancer., PMID:38302471
Anti-PD-L1 therapy altered inflammation but not survival in a lethal murine hepatitis virus-1 pneumonia model., PMID:38259435
Generation and Application of Monoclonal Antibodies against Porcine S100A8, S100A9, and S100A12 Proteins Using Hybridoma Technology., PMID:38256103
Calprotectin Impairs Platelet Survival in Patients With Primary Antiphospholipid Syndrome., PMID:38225923
CD146 deficiency aggravates chronic obstructive pulmonary disease via the increased production of S100A9 and MMP-9 in macrophages., PMID:38109838
CD147: an integral and potential molecule to abrogate hallmarks of cancer., PMID:38023152
Targeting TAM-secreted S100A9 effectively enhances the tumor-suppressive effect of metformin in treating lung adenocarcinoma., PMID:38008395
Effect of Proinflammatory S100A9 Protein on Migration and Proliferation of Microglial Cells., PMID:37947991
Topical anti-TNF-a ssDNA aptamer decreased the imiquimod induced psoriatic inflammation in BALB/c mice., PMID:37879125
Viral nanoparticle vaccines against S100A9 reduce lung tumor seeding and metastasis., PMID:37844250
S100a9 inhibits Atg9a transcription and participates in suppression of autophagy in cardiomyocytes induced by β1-adrenoceptor autoantibodies., PMID:37723445
Single-cell multi-omics sequencing reveals the immunological disturbance underlying STAT3-V637M Hyper-IgE syndrome., PMID:37480751
Circulating neutrophils activated by cancer cells and M2 macrophages promote gastric cancer progression during PD-1 antibody-based immunotherapy., PMID:37333017
Molecular Signatures in Swine Innate and Adaptive Immune Responses to African Swine Fever Virus Antigens p30/p54/CD2v Expressed Using a Highly Efficient Semliki Forest Virus Replicon System., PMID:37298266
Socs3 expression in myeloid cells modulates the pathogenesis of dextran sulfate sodium (DSS)-induced colitis., PMID:37283760
Unraveling CD69 signaling pathways, ligands and laterally associated molecules., PMID:37223078
Real-World Effectiveness of Nirmatrelvir/Ritonavir on Coronavirus Disease 2019-Associated Hospitalization Prevention: A Population-based Cohort Study in the Province of Quebec, Canada., PMID:37149726
Targeted Transcriptional Analysis of IgA Vasculitis, IgA Nephropathy, and IgA-Dominant Infection-Related Glomerulonephritis Reveals Both Distinct and Overlapping Immune Signatures., PMID:37036681
Desmoglein-Specific B-Cell-Targeted Single-Cell Analysis Revealing Unique Gene Regulation in Patients with Pemphigus., PMID:36997112
Immune Profiling Panel Gene Set Identifies Critically Ill Patients With Low Monocyte Human Leukocyte Antigen-DR Expression: Preliminary Results From the REAnimation Low Immune Status Marker (REALISM) Study., PMID:36917594
A single-dose Qβ VLP vaccine against S100A9 protein reduces atherosclerosis in a preclinical model., PMID:36570039
Corroboration of cross-reactivity between Mycobacterium leprae and hosts' salivary and cutaneous proteins: A hope for prognostic biomarkers for the pathogenesis of reactions in leprosy., PMID:36560940
S100A9 upregulated by IFNGR signaling blockade functions as a novel GVHD suppressor without compromising GVL in mice., PMID:36477272
Cerebral Expression of the Neuregulin-1 Gene NRG1 during Induced Spatial Memory Impairment and Its Reversal in Aging Mice., PMID:36437318
Angelica oil restores the intestinal barrier function by suppressing S100A8/A9 signalling in mice with ulcerative colitis., PMID:36332386
S100A9‑containing serum exosomes obtained from patients with burn injuries promote myocardial cell pyroptosis through NLRP3., PMID:36277145
Ablation of Basic Leucine Zipper Transcription Factor ATF-Like Potentiates Estradiol to Induce Atopic Dermatitis., PMID:36160706
Inhibiting S100A8/A9 attenuates airway obstruction in a mouse model of heterotopic tracheal transplantation., PMID:36113182
Calprotectin (S100A8/S100A9) detects inflammatory activity in rheumatoid arthritis patients receiving tocilizumab therapy., PMID:35986420
Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation., PMID:35949314
Experimental Study of a Quad-Band Metamaterial-Based Plasmonic Perfect Absorber as a Biosensor., PMID:35889446
Identified potential biomarkers may predict primary nonresponse to infliximab in patients with ulcerative colitis., PMID:35876170
Proteomic analysis of infected root canals with apical periodontitis in patients with type 2 diabetes mellitus: A cross-sectional study., PMID:35766999
For research use only. Not for human or drug use.
