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Anti-APP Antibody (R1J89)

Catalog #:   RHC12514 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, IP, WB
Accession: P05067
Overview

Catalog No.

RHC12514

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Applications

IF, IHC, IP, WB

Recommended Dilution

Application Dilution
IF 1:50-1:200, IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000

Target

AICD-57, A4, Beta-CTF, Protease nexin-II, Gamma-CTF(50), ABPP, S-APP-beta, APP, Abeta40, Abeta42, AID(59), Amyloid intracellular domain 59, AID(57), S-APP-alpha, Gamma-CTF(59), Beta-secretase C-terminal fragment, Amyloid-beta precursor protein, Amyloid precursor protein, Beta-APP42, PreA4, Alzheimer disease amyloid protein, APPI, PN-II, AICD-59, Alpha-secretase C-terminal fragment, Amyloid-beta A4 protein, Amyloid intracellular domain 57, CVAP, Amyloid intracellular domain 50, Beta-APP40, AD1, Cerebral vascular amyloid peptide, AID(50), Alpha-CTF, Gamma-CTF(57), AICD-50

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05067

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1J89

Note

For research use only.

Data Image
  • Immunofluorescence
    Immunocytochemistry analysis of Amyloid Precursor Protein (green) in Hela using Amyloid Precursor Protein antibody,and DAPI(blue).
  • Immunohistochemical
    Immunohistochemistry analysis of paraffin-embedded Human brain using Amyloid Precursor Protein antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot
    Western blot analysis of Amyloid Precursor Protein in rat Brain, 3T3, Hela lysates using Amyloid Precursor Protein antibody
References

Improved glycemic and weight control with Dulaglutide addition in SGLT2 inhibitor treated obese type 2 diabetic patients at high cardiovascular risk in a real-world setting. The AWARE-2 study., PMID:39613122

Intranasal trivalent candidate vaccine induces strong mucosal and systemic immune responses against Neisseria gonorrhoeae., PMID:39660148

Standardly Trained Peer Volunteer-Led, Social App Recruiting-Based Human Immunodeficiency Virus Testing Strategy Using Rapid Testing Kits (SPARK) Among Men Who Have Sex With Men: A Population-Based Survey Evaluation., PMID:39679350

Neuroinflammation-targeted magnetic resonance imaging nanoprobes for the early diagnosis of Alzheimer's disease., PMID:39686760

Neprilysin-Mediated Amyloid Beta Clearance and Its Therapeutic Implications in Neurodegenerative Disorders., PMID:39698259

Effectiveness of a Novel PLA2R1 Knock-in Middle Age Rat Model in Repairing Renal Function Damage., PMID:39702946

Acute Communication Between Microglia and Nonparenchymal Immune Cells in the Anti-Aβ Antibody-Injected Cortex., PMID:39741000

Immunohistochemical labeling of ongoing axonal degeneration 10 days following cervical contusion spinal cord injury in the rat., PMID:39753895

Smartphone-based mobile digital pressure sensor for quantitative point-of-care testing of respiratory syncytial virus infection., PMID:39756256

Can GastroPanel be used as a triage tool to select patients with advanced atrophic gastritis for gastroscopy? A prospective clinical validation study., PMID:39762070

Equipmentless point-of-care testing of dengue antibodies using ELISA and smartphones., PMID:39787848

Toward curing neurological autoimmune disorders: Biomarkers, immunological mechanisms, and therapeutic targets., PMID:39809275

Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy., PMID:39813317

Magnetofluidic-Assisted Portable Automated Microfluidic Devices for Protein Detection., PMID:39815389

Immunotherapy-Resistant Neuropathic Pain and Fatigue Predict Quality-of-Life in Contactin-Associated Protein-Like 2 Antibody Disease., PMID:39825737

Immunogenicity and vaccine efficacy of Actinobacillus pleuropneumoniae-derived extracellular vesicles as a novel vaccine candidate., PMID:39831520

Bone marrow mesenchymal stem cells derived cytokines associated with AKT/IAPs signaling ameliorate Alzheimer's disease development., PMID:39849525

Concepts and Methods for Predicting Viral Evolution., PMID:39890732

Predicting and validating the risk of interstitial lung disease in systemic lupus erythematosus., PMID:39986125

Capturing what matters: Patient-reported LGI1-ANTibody encephalitis outcome RatiNg scale (LANTERN)., PMID:39996410

Individual Genomic Loci, Transcript Level and Serum Profile of Immune, Antioxidant and Hormonal Markers Associated with Sheep Arthritis., PMID:40005882

Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer's disease., PMID:40027647

A novel flow through assay and smartphone application based prototype for point-of-care diagnosis of tuberculosis., PMID:40049786

Spatial prediction of immunity gaps during a pandemic to inform decision making: A geostatistical case study of COVID-19 in Dominican Republic., PMID:40074535

Combination therapy with Chicoric acid and PD-1/PD-L1 blockade improves the immunotherapy response in patient-derived ovarian cancer xenograft model., PMID:40087780

Multianalyte Nanopore Detection of Alzheimer's Biomarkers: A Label-Free Platform with Improved Sensitivity and Range., PMID:40129019

Distinguishing Low Expression Levels of Human Epidermal Growth Factor Receptor 2 in Breast Cancer: Insights from Qualitative and Quantitative Magnetic Resonance Imaging Analysis., PMID:40137571

Establishing the lowest penicillin concentration to prevent pharyngitis due to Streptococcus pyogenes using a human challenge model (CHIPS): a randomised, double-blind, placebo-controlled trial., PMID:40157384

Clinical Benefits and Risks of Antiamyloid Antibodies in Sporadic Alzheimer Disease: Systematic Review and Network Meta-Analysis With a Web Application., PMID:40194268

Novel Approaches to Track Neurodegeneration in Murine Models of Alzheimer's Disease Reveal Previously Unknown Aspects of Extracellular Aggregate Deposition., PMID:40236040

Combination of anlotinib with immunotherapy enhanced both anti-angiogenesis and immune response in high-grade serous ovarian cancer., PMID:40260248

Novel Soluble apxIVA-Truncated Protein and Its Application to Rapid Detection and Distinction of Actinobacillus pleuropneumoniae Wild-Strain-Infected Samples from Those Vaccinated with apxIV-Partially Deleted Vaccine., PMID:40266988

Blockage of CCL3 with neutralizing antibody reduces neuroinflammation and reverses Alzheimer disease phenotypes., PMID:40268067

Field Evaluation of a Ready-to-Use Porcine Circovirus Type 2 and Mycoplasma hyopneumoniae Vaccine in Naturally Infected Farms in Taiwan., PMID:40284806

Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs., PMID:40307937

Strategies Beyond 3rd EGFR-TKI Acquired Resistance: Opportunities and Challenges., PMID:40322930

Development and Characterization of a Recombinant galT-galU Protein for Broad-Spectrum Immunoprotection Against Porcine Contagious Pleuropneumonia., PMID:40332240

Probe-free and wash-free strategy for on-site testing of chloramphenicol in food based on differential encodable microspheres separation system., PMID:40359682

A fully automated paper-based smartphone-assisted microfluidic chemiluminescence sample to result immunoassay platform., PMID:40374237

Co-occurrence of Down Syndrome and Multiple Sclerosis., PMID:40395918

Discovery of an APP-selective BACE1 inhibitor for Alzheimer's disease., PMID:40399225

Live attenuated hfq-deleted Acinetobacter baumannii vaccine provides protection against systemic infection., PMID:40412336

Immune impacts of infant whole-cell and acellular pertussis vaccination on co-administered vaccines., PMID:40414565

PET imaging of TREM2 in amyloid-beta induced neuroinflammation., PMID:40434494

Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life., PMID:40442822

Anti-pyroglutamate-3 Aβ immunotherapy engages microglia and inhibits amyloid accumulation in transgenic mouse models of Aβ amyloidosis., PMID:40455292

Soluble VCAM-1 may serve as a pharmacodynamic CSF marker to monitor BACE2 activity in non-human primates., PMID:40480341

β-Amyloid as a new target to suppress tonic PTH hypersecretion in primary hyperparathyroidism., PMID:40492090

Enhancing Human Post-Exposure Rabies Prophylaxis in Canine Rabies Endemic Regions With an Interactive Web Solution., PMID:40496118

Unique lipid cargoes in APOE4 human brain-derived extracellular vesicles recruit cell adhesion molecules and promote tauopathy in Alzheimer's disease., PMID:40502793

Datasheet

Document Download

Anti-APP Antibody (R1J89).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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Mail: support@antibodysystem.com

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For research use only. Not for human or drug use.

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Anti-APP Antibody (R1J89) [RHC12514]
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