Catalog No.
YHC27501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys29-Gln242
Predicted molecular weight
27.05 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07738
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
2,3-bisphosphoglycerate mutase, erythrocyte, 2,3-diphosphoglycerate mutase, BPGM, DPGM, BPG-dependent PGAM, Bisphosphoglycerate mutase, 2,3-bisphosphoglycerate synthase
In vitro protein expression profile of cultivated muscle cells from Labeo rohita., PMID:39966484
Longevity Humans Have Youthful Erythrocyte Function and Metabolic Signatures., PMID:39924931
The difference between young and older ducks: Amino acid, free fatty acid, nucleotide compositions and breast muscle proteome., PMID:39810946
Beyond hemoglobin: Critical role of 2,3-bisphosphoglycerate mutase in kidney function and injury., PMID:39422260
Diagnostic Approaches to Investigate JAK2-Unmutated Erythrocytosis Based on a Single Tertiary Center Experience., PMID:38568469
Alteration in the number, morphology, function, and metabolism of erythrocytes in high-altitude polycythemia., PMID:38426208
Biphosphoglycerate Mutase: A Novel Therapeutic Target for Malaria?, PMID:37827586
Erythrocyte ENT1-AMPD3 Axis is an Essential Purinergic Hypoxia Sensor and Energy Regulator Combating CKD in a Mouse Model., PMID:37725437
Analysis of the role of glucose metabolism-related genes in dilated cardiomyopathy based on bioinformatics., PMID:37559624
Proteomics analyses of acute kidney injury biomarkers in a rat exertional heat stroke model., PMID:37378075
Screening of activators of 2,3-diphosphoglycerate mutase from traditional Chinese herb medicines., PMID:37202106
Enhanced BPGM/2,3-DPG pathway activity suppresses glycolysis in hypoxic astrocytes via FIH-1 and TET2., PMID:36334804
Heterozygosity for bisphosphoglycerate mutase deficiency expressing clinically as congenital erythrocytosis: A case series and literature review., PMID:36177683
Moxibustion attenuates inflammation and alleviates axial spondyloarthritis in mice: Possible role of APOE in the inhibition of the Wnt pathway., PMID:36081820
Diagnosis and genetic analysis of polycythemia in children and a novel EPAS1 gene mutation., PMID:36002380
Bcl11a and the Correlated Key Genes Ascribable to Globin Switching: An In-silico Study., PMID:35718959
Screening of Potential Biomarkers in the Peripheral Serum for Steroid-Induced Osteonecrosis of the Femoral Head Based on WGCNA and Machine Learning Algorithms., PMID:35154510
Erythrocytosis associated with EPAS1(HIF2A), EGLN1(PHD2), VHL, EPOR or BPGM mutations: The Mayo Clinic experience., PMID:35142155
Black phosphorus nanoparticles for dual therapy of non-small cell lung cancer., PMID:35078385
Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming., PMID:34138843
Dysregulation of bisphosphoglycerate mutase during in vitro maturation of oocytes., PMID:34052998
Involvement of glycolysis activation in flatfish sexual size dimorphism: Insights from transcriptomic analyses of Platichthys stellatus and Cynoglossus semilaevis., PMID:33930775
Differential proteomic analysis of children infected with respiratory syncytial virus., PMID:33656056
Hydrogen Sulfide Is a Regulator of Hemoglobin Oxygen-Carrying Capacity via Controlling 2,3-BPG Production in Erythrocytes., PMID:33628390
Erythrocytosis: genes and pathways involved in disease development., PMID:33370224
A broad diversity in oxygen affinity to haemoglobin., PMID:33037242
Bisphosphoglycerate Mutase Deficiency Protects against Cerebral Malaria and Severe Malaria-Induced Anemia., PMID:32966787
Analysis of plasma metabolic profile, characteristics and enzymes in the progression from chronic hepatitis B to hepatocellular carcinoma., PMID:32701483
Cardiac Transcriptome Analysis Reveals Nr4a1 Mediated Glucose Metabolism Dysregulation in Response to High-Fat Diet., PMID:32610475
Maternal erythrocyte ENT1-mediated AMPK activation counteracts placental hypoxia and supports fetal growth., PMID:32434995
Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies., PMID:32284030
Algorithmic evaluation of hereditary erythrocytosis: Pathways and caveats., PMID:31069987
Haemoglobin expression in in vivo murine preimplantation embryos suggests a role in oxygen-regulated gene expression., PMID:30482269
Contextual fear conditioning modulates the gene expression over time., PMID:30039834
Genotype-Phenotype Correlation of Hereditary Erythrocytosis Mutations, a single center experience., PMID:29790589
Genetic basis of congenital erythrocytosis., PMID:29741264
Gene panel sequencing improves the diagnostic work-up of patients with idiopathic erythrocytosis and identifies new mutations., PMID:27651169
A Novel Hemoglobin Variant Associated with Congenital Erythrocytosis: Hb Seoul [β86(F2)Ala→Thr] (HBB:c.259G>A)., PMID:27312559
Associations between Serum Sex Hormone Concentrations and Whole Blood Gene Expression Profiles in the General Population., PMID:26001193
Hereditary erythrocytosis, thrombocytosis and neutrophilia., PMID:25189721
Genetic basis of congenital erythrocytosis: mutation update and online databases., PMID:24115288
Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt., PMID:18413611
Maternal housekeeping proteins translated during bovine oocyte maturation and early embryo development., PMID:16739132
Crystal structure of human B-type phosphoglycerate mutase bound with citrate., PMID:15883004
Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays., PMID:15199147
Expression of an Arabidopsis phosphoglycerate mutase homologue is localized to apical meristems, regulated by hormones, and induced by sedentary plant-parasitic nematodes., PMID:15010616
Assignment of laminin B1 polypeptide (LAMB1) and 2,3 bisphosphoglycerate mutase (BPGM) to the physical and genetic maps of BTA4., PMID:11086543
Human erythrocyte bisphosphoglycerate mutase: inactivation by glycation in vivo and in vitro., PMID:9832630
An enzyme-linked immunosorbent assay and reference ranges for bisphosphoglycerate mutase in human erythrocytes., PMID:9773955
Critical role of human bisphosphoglycerate mutase Cys22 in the phosphatase activator-binding site., PMID:9162026