Catalog No.
YHC25601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys162-His504
Predicted molecular weight
41.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07358
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C8B, Complement component C8 beta chain, Complement component 8 subunit beta
Proteomic and In Silico Analyses Highlight Complement System's Role in Bladder Cancer Immune Regulation., PMID:40283026
Protective Vaccination of Mice Against Blood-Stage Malaria Impacts Hepatic Expression of Genes Encoding Acute-Phase Proteins and IL-6 Family Members., PMID:40243929
Bioinformatics-Guided Identification and Quantification of Biomarkers of Crotalus atrox Envenoming and Its Neutralization by Antivenom., PMID:40147718
Genome-wide mapping of complement system proteins for islet autoimmunity in the DAISY and TEDDY children., PMID:39989961
Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia., PMID:39361088
Hepatocyte nuclear factor 4α is a critical factor for the production of complement components in the liver., PMID:39285151
The temporal protein signature analyses of developing human deciduous molar tooth germ., PMID:38522031
Exosome-Related FTCD Facilitates M1 Macrophage Polarization and Impacts the Prognosis of Hepatocellular Carcinoma., PMID:38254641
Proteomic Biomarkers for the Prediction of Transition to Psychosis in Individuals at Clinical High Risk: A Multi-cohort Model Development Study., PMID:38243809
Comparative transcriptome analysis reveals potential regulatory mechanisms of genes and immune pathways following Vibrio harveyi infection in red drum (Sciaenops ocellatus)., PMID:38242261
Comparative Proteomic Analysis of Exosomes Derived from Patients Infected with Non-Tuberculous Mycobacterium and Mycobacterium tuberculosis., PMID:37764178
Global-feature of autoimmune glomerulonephritis using proteomic analysis of laser capture microdissected glomeruli., PMID:37033921
Combined Heterozygous Genetic Variations in Complement C2 and C8B: An Explanation for Multidimensional Immune Imbalance?, PMID:36858027
Quantitative proteomics reveal three potential biomarkers for risk assessment of acute myocardial infarction., PMID:35156527
Comparative Analysis of Serum Proteins Between Hepatitis B Virus Genotypes B and C Infection by DIA-Based Quantitative Proteomics., PMID:34795487
Quantitative proteomics by iTRAQ-PRM based reveals the new characterization for gout., PMID:34635120
Proteomic analysis of liver tissues in chicken embryo at Day 16 and Day 20 reveals antioxidant mechanisms., PMID:33962068
Aqueous Humor Proteomic Alterations Associated with Visual Field Index Parameters in Glaucoma Patients: A Pilot Study., PMID:33808966
Development of predicitve models to distinguish metals from non-metal toxicants, and individual metal from one another., PMID:33272211
Fish complement C8 evolution, functional network analyses, and the theoretical interaction between C8 alpha chain and CD59., PMID:33160183
Bioinformatics analysis of key biomarkers and potential molecular mechanisms in hepatocellular carcinoma induced by hepatitis B virus., PMID:32443377
mRNA expression disturbance of complement system related genes in acute arterial thrombotic and paroxysmal atrial fibrillation patients., PMID:32389013
Exome-based search for recurrent disease-causing alleles in Russian population., PMID:31028847
Whole-exome sequencing detects mutations in pediatric patients with atypical hemolytic uremic syndrome in Taiwan., PMID:30905589
Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress., PMID:30635638
Cryptophane Nanoscale Assemblies Expand 129Xe NMR Biosensing., PMID:29782149
Molecular characterization and expression analysis of complement component 3 in dojo loach (Misgurnus anguillicaudatus)., PMID:29155029
iTRAQ-Based Quantitative Proteomics Analysis of the Protective Effect of Yinchenwuling Powder on Hyperlipidemic Rats., PMID:28883884
Inflammation Thread Runs across Medical Laboratory Specialities., PMID:27493451
Invasive meningococcal disease in three siblings with hereditary deficiency of the 8(th) component of complement: evidence for the importance of an early diagnosis., PMID:27183977
The complement system of elasmobranches revealed by liver transcriptome analysis of a hammerhead shark, Sphyrna zygaena., PMID:26987526
Susceptibility to invasive meningococcal disease: polymorphism of complement system genes and Neisseria meningitidis factor H binding protein., PMID:25798599
Myelin basic protein undergoes a broader range of modifications in mammals than in lower vertebrates., PMID:22420465
The three-way relationship of polymorphisms of porcine genes encoding terminal complement components, their differential expression, and health-related phenotypes., PMID:21645298
Molecular cloning of the terminal complement components C6 and C8beta of cartilaginous fish., PMID:19716423
Effects of nonylphenol on hepatic testosterone metabolism and the expression of acute phase proteins in winter flounder (Pleuronectes americanus): comparison to the effects of Saint John's Wort., PMID:15792627
Transcriptional analysis of human peripheral blood mononuclear cells after influenza immunization., PMID:15364265
1H-cyclopenta[b]benzofuran lignans from Aglaia species inhibit cell proliferation and alter cell cycle distribution in human monocytic leukemia cell lines., PMID:10685499
Molecular, genetic, and functional analysis of homozygous C8 beta-chain deficiency in two siblings., PMID:9476133
The human complement C8G gene, a member of the lipocalin gene family: polymorphisms and mapping to chromosome 9q34.3., PMID:8865989
Mapping of the OB receptor to 1p in a region of nonconserved gene order from mouse and rat to human., PMID:8743992
Detection of heterozygous C8 beta deficiency by PCR in a healthy Italian population., PMID:9165271
The isolation and characterization of four myelin basic proteins from the unbound fraction during CM52 chromatography., PMID:7574672
Structure of the human C7 gene and comparison with the C6, C8A, C8B, and C9 genes., PMID:7730625
Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus., PMID:7665162
Expression of the complement C8 genes during interleukin-6-mediated in vitro induction of the acute-phase response., PMID:7710765
Simultaneous expression of kappa and lambda light chains in a murine IgG3 anti-Cryptococcus neoformans hybridoma cell line., PMID:7737677
Polymorphism of the complement C8A and -B genes in two families with C8 beta deficiency and neisserial infections., PMID:8020197
Human complement component C8. Molecular basis of the beta-chain polymorphism., PMID:8131848
The human complement component C8B gene: structure and phylogenetic relationship., PMID:8365729