Catalog No.
RHB82202
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
PTTG1, Esp1-associated protein, EAP1, Securin, TUTR1, PTTG, hPTTG, Pituitary tumor-transforming gene 1 protein, Tumor-transforming protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95997
Applications
FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1G84
Valproic acid promotes transcriptional activation of Drd2 by mediating histone acetylation to inhibit the mTOR-Pttg1 signaling axis and exerts anti-PitNETs activity., PMID:40220407
Bioinformatic Analysis of PTTG Family and Prognosis and Immune Cell Infiltration in Gastric Cancer., PMID:36785594
Unravelling the diagnostic and therapeutic potentialities of a novel RNA aptamer isolated against human pituitary tumour transforming gene 1 (PTTG1) protein., PMID:33161980
Protein Expression of PTTG-1, OCT-4, and KLF-4 in Seminoma: A Pilot Study., PMID:31572301
Hormonal aggressiveness according to the expression of cellular markers in corticotroph adenomas., PMID:30474823
Polymorphisms associated with etanercept response in moderate-to-severe plaque psoriasis., PMID:28470127
Identification of Antibody Against SNRPB, Small Nuclear Ribonucleoprotein-Associated Proteins B and B', as an Autoantibody Marker in Crohn's Disease using an Immunoproteomics Approach., PMID:28204086
Prognostic implications of securin expression and sub-cellular localization in human breast cancer., PMID:26984614
Expression of the pituitary tumor transforming gene (PTTG1) in pheochromocytoma as a potential marker for distinguishing benign versus malignant tumors., PMID:25871022
Novel antigens in non-small cell lung cancer: SP17, AKAP4, and PTTG1 are potential immunotherapeutic targets., PMID:25739119
Involvement of pituitary tumor transforming gene 1 in psoriasis, seborrheic keratosis, and skin tumors., PMID:25549700
SUMO-1 plays crucial roles for spindle organization, chromosome congression, and chromosome segregation during mouse oocyte meiotic maturation., PMID:25123474
Regulated genes in psoriatic skin during treatment with fumaric acid esters., PMID:24852654
Pituitary-tumour-transforming-gene 1 expression in testicular cancer., PMID:24754453
Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells., PMID:23867215
Transgenesis-mediated reproductive dysfunction and tumorigenesis: effects of immunological neutralization., PMID:23226476
Prognostic significance of pituitary tumour-transforming gene-binding factor (PBF) expression in papillary thyroid carcinoma., PMID:22888961
Expression of Ki-67, PTTG1, FGFR4, and SSTR 2, 3, and 5 in nonfunctioning pituitary adenomas: a high throughput TMA, immunohistochemical study., PMID:22419713
PTTG1/securin modulates microtubule nucleation and cell migration., PMID:21937724
Role of the pituitary tumor transforming gene 1 in the progression of hepatocellular carcinoma., PMID:21099350
TrkB antibody elicits cytotoxicity and suppresses migration/invasion of transitional cell carcinoma cells., PMID:20811716
Immunohistochemical expression of pituitary tumor transforming gene (PTTG) in pituitary adenomas: a correlative study of tumor subtypes., PMID:20106827
E2F1 induces pituitary tumor transforming gene (PTTG1) expression in human pituitary tumors., PMID:19837943
The pituitary tumor transforming gene 1 (PTTG-1): an immunological target for multiple myeloma., PMID:18384692
Expression of pituitary tumor-transforming gene in endometrial cancer as a prognostic marker., PMID:18217976
Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2)., PMID:17096843
Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cells., PMID:17065388
Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells., PMID:16959877
Essential CDK1-inhibitory role for separase during meiosis I in vertebrate oocytes., PMID:16906143
Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction., PMID:16868023
The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells., PMID:16219911
Ufd2, a novel autoantigen in scleroderma, regulates sister chromatid separation., PMID:15611659
Expression of pituitary tumor transforming gene (PTTG) and its binding protein in human astrocytes and astrocytoma cells: function and regulation of PTTG in U87 astrocytoma cells., PMID:15178645
Expression and function of pituitary tumour transforming gene for T-lymphocyte activation., PMID:12472590
Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors., PMID:12213878
Characterization of a polyclonal antibody to human pituitary tumor transforming gene 1 (PTTG1) protein., PMID:11724901
Human pituitary tumor-transforming gene induces angiogenesis., PMID:11158059
Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter., PMID:10650958
For research use only. Not for human or drug use.
