Catalog No.
RHB76101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
CLDN1, Senescence-associated epithelial membrane protein, CLD1, Claudin-1, SEMP1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95832
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1G73
Note
For research use only.
Claudin-1 Binder Enhances Epidermal Permeability in a Human Keratinocyte Model., PMID:26139628
Novel human anti-claudin 1 mAbs inhibit hepatitis C virus infection and may synergize with anti-SRB1 mAb., PMID:26519290
Claudin-1, -3, -4 and -7 gene expression analyses in canine prostate carcinoma and mammary tissue derived cell lines., PMID:26774145
Analysis of the expression and localization of tight junction transmembrane proteins, claudin-1, -4, -7, occludin and JAM-A, in human cervical adenocarcinoma., PMID:26847087
Immunohistological study of tight junction protein expression in mal de Meleda., PMID:26986447
EpCAM Expressed by Murine Epidermal Langerhans Cells Modulates Immunization to an Epicutaneously Applied Protein Antigen., PMID:27106675
MicroRNA-142-5p contributes to Hashimoto's thyroiditis by targeting CLDN1., PMID:27277258
Generation and characterization of a human-mouse chimeric antibody against the extracellular domain of claudin-1 for cancer therapy using a mouse model., PMID:27286708
Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition., PMID:27298373
Claudin-1 Protein Expression Is a Good Prognostic Factor in Non-Small Cell Lung Cancer, but only in Squamous Cell Carcinoma Cases., PMID:27687058
Aberrant expression of the tight junction molecules claudin-1 and zonula occludens-1 mediates cell growth and invasion in oral squamous cell carcinoma., PMID:27436828
Multivacuolated mucin-filled cells: a unique cell characteristic of plexiform neurofibroma. A report of 11 cases., PMID:27816720
Claudin-Low Breast Cancer; Clinical & Pathological Characteristics., PMID:28045912
Humanisation of a claudin-1-specific monoclonal antibody for clinical prevention and cure of HCV infection without escape., PMID:28360099
Claudin-targeted drug development using anti-claudin monoclonal antibodies to treat hepatitis and cancer., PMID:28415141
Cimifugin suppresses allergic inflammation by reducing epithelial derived initiative key factors via regulating tight junctions., PMID:28597545
Antibody targeting of claudin-1 as a potential colorectal cancer therapy., PMID:28659146
Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function., PMID:28967978
Monoclonal Antibodies against Occludin Completely Prevented Hepatitis C Virus Infection in a Mouse Model., PMID:29437969
Matrix metalloproteinase-9 (MMP9) is involved in the TNF-α-induced fusion of human M13SV1-Cre breast epithelial cells and human MDA-MB-435-pFDR1 cancer cells., PMID:29636110
A long non-coding SINEUP RNA boosts semi-stable production of fully human monoclonal antibodies in HEK293E cells., PMID:29658818
Tight junction proteins in gastrointestinal and liver disease., PMID:30297438
Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs., PMID:30530622
In vivo combination of human anti-envelope glycoprotein E2 and -Claudin-1 monoclonal antibodies for prevention of hepatitis C virus infection., PMID:30599173
Anti-Claudin-1 Conjugated to a Near-Infrared Fluorophore Targets Colon Cancer in PDOX Mouse Models., PMID:31077946
Gold nanoparticles regulate tight junctions and improve cetuximab effect in colon cancer cells., PMID:31215349
Toll-like receptor 2 stimulation augments esophageal barrier integrity., PMID:31267532
Peptides Derived from the Tight Junction Protein CLDN1 Disrupt the Skin Barrier and Promote Responsiveness to an Epicutaneous Vaccine., PMID:31381894
δ Opioid Receptor Agonism Preserves the Retinal Pigmented Epithelial Cell Tight Junctions and Ameliorates the Retinopathy in Experimental Diabetes., PMID:31529081
Lubiprostone Induces Claudin-1 and Protects Intestinal Barrier Function., PMID:31536982
Integrated Imaging Methodology Detects Claudin-1 Expression in Premalignant Nonpolypoid and Polypoid Colonic Epithelium in Mice., PMID:31922993
Targeting claudin-4 enhances chemosensitivity in breast cancer., PMID:32086991
Hepatitis C virus infection and tight junction proteins: The ties that bind., PMID:32268133
COMMD8 changes expression during initial phase of wasp venom immunotherapy., PMID:32559011
Dietary supplementation with polysaccharides from Ziziphus Jujuba cv. Pozao intervenes in immune response via regulating peripheral immunity and intestinal barrier function in cyclophosphamide-induced mice., PMID:32697211
HMGB1 enhances epithelial permeability via p63/TGF-β signaling in lung and terminal bronchial epithelial cells., PMID:32857676
Previous Influenza Infection Exacerbates Allergen Specific Response and Impairs Airway Barrier Integrity in Pre-Sensitized Mice., PMID:34445491
Claudins and Gastric Cancer: An Overview., PMID:35053454
Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment., PMID:36309131
A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity., PMID:36542691
Tight Junction Protein Signaling and Cancer Biology., PMID:36672179
Establishment of Epithelial Inflammatory Injury Model Using Intestinal Organoid Cultures., PMID:36926182
Improving the response to oxaliplatin by targeting chemotherapy-induced CLDN1 in resistant metastatic colorectal cancer cells., PMID:37041570
Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer., PMID:37585503
Effect of Lactobacillus salivarius SNK-6 on egg quality, intestinal morphology, and cecal microbial community of laying hens., PMID:37980753
Targeting IL-13 with tralokinumab normalizes type 2 inflammation in atopic dermatitis both early and at 2 years., PMID:38563683
Tight Junction Proteins as Therapeutic Targets to Treat Liver Fibrosis and Hepatocellular Carcinoma., PMID:38648796
Claudin 1, 4, 6 and 18 isoform 2 as targets for the treatment of cancer (Review)., PMID:39301632
Expression Profiles of Five Common Cancer Membrane Protein Antigens Collected for the Development of Cocktail CAR-T Cell Therapies Applicable to Most Solid Cancer Patients., PMID:40076777
Enhanced visualization of colonic polyps using a fluorophore-conjugated claudin-1 antibody in a CPC-APC mouse model., PMID:40517099
For research use only. Not for human or drug use.
