Catalog No.
RHB75602
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Applications
WB
Recommended Dilution
| Application |
Dilution |
| WB |
1:500-1:1000 |
Target
Docking protein CAIR-1, BAG3, Bcl-2-associated athanogene 3, BAG family molecular chaperone regulator 3, Bcl-2-binding protein Bis, BAG-3, BIS
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95817
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1G72
Note
For research use only.
Reactive astrocytes express bis, a bcl-2-binding protein, after transient forebrain ischemia., PMID:12061864
Induction of Bis, a Bcl-2-binding protein, in reactive astrocytes of the rat hippocampus following kainic acid-induced seizure., PMID:12085992
Regulation by heavy metals and temperature of the human BAG-3 gene, a modulator of Hsp70 activity., PMID:12706811
BAG3 protein regulates cell survival in childhood acute lymphoblastic leukemia cells., PMID:14614315
Protein quantification by chemiluminescent Western blotting: elimination of the antibody factor by dilution series and calibration curve., PMID:20035759
The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases., PMID:21696420
Delineation of apoptotic genes for synergistic apoptosis of lexatumumab and anthracyclines in human renal cell carcinoma cells by polymerase chain reaction array., PMID:22205156
Expression of Bis in the mouse gastrointestinal system., PMID:23094204
Detection of soluble BAG3 and anti-BAG3 antibodies in patients with chronic heart failure., PMID:23412388
BAG3 is a novel serum biomarker for pancreatic adenocarcinomas., PMID:23821002
BAG3 protein expression in melanoma metastatic lymph nodes correlates with patients' survival., PMID:24722298
Insight into PreImplantation Factor (PIF*) mechanism for embryo protection and development: target oxidative stress and protein misfolding (PDI and HSP) through essential RIKP [corrected] binding site., PMID:24983882
The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth., PMID:25149536
BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages., PMID:26522614
Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling., PMID:27321750
Protein Cross-Linking Capillary Electrophoresis for Protein-Protein Interaction Analysis., PMID:27434096
Expression of the anti-apoptotic BAG3 protein in leg venous ulcerative tissues., PMID:27551493
PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment., PMID:28103122
Combined effect of anti-BAG3 and anti-PD-1 treatment on macrophage infiltrate, CD8+ T cell number and tumour growth in pancreatic cancer., PMID:28801350
Role of BAG3 in cancer progression: A therapeutic opportunity., PMID:28864347
The anti-apoptotic BAG3 protein is involved in BRAF inhibitor resistance in melanoma cells., PMID:29113311
BAG3 promotes the phenotypic transformation of primary rat vascular smooth muscle cells via TRAIL., PMID:29484366
Identification of BAG3 target proteins in anaplastic thyroid cancer cells by proteomic analysis., PMID:29487711
Chaperone-assisted selective autophagy in healthy and papillomavirus-associated neoplastic urothelium of cattle., PMID:29981700
Development of an anti-BAG3 humanized antibody for treatment of pancreatic cancer., PMID:30973679
BAG3 induces fibroblasts to release key cytokines involved in pancreatic cell migration., PMID:34741485
Concerted BAG3 and SIRPα blockade impairs pancreatic tumor growth., PMID:35241649
Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338
Pancreatic Cancer-Secreted Proteins: Targeting Their Functions in Tumor Microenvironment., PMID:37835519
Anti-Ku + myositis: an acquired inflammatory protein-aggregate myopathy., PMID:39012547
For research use only. Not for human or drug use.
