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Anti-RAPGEF3/EPAC 1 Antibody (R1G47)

Catalog #:   RHB63702 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, IP, WB
Accession: O95398
Overview

Catalog No.

RHB63702

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000

Target

RAPGEF3, cAMP-GEFI, cAMP-regulated guanine nucleotide exchange factor I, EPAC1, EPAC 1, Exchange protein directly activated by cAMP 1, Rap guanine nucleotide exchange factor 3, Exchange factor directly activated by cAMP 1, Rap1 guanine-nucleotide-exchange factor directly activated by cAMP, EPAC, CGEF1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O95398

Applications

IF, IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1G47

Data Image
  • Western blot
    Western blot analysis of Epac1 expression in HeLa cell lysate.
References

Follicular Lymphoma: Current Therapeutic Landscape and Future Prospects., PMID:40517443

Advances in the Management of Relapsed/Refractory CLL and Richter Transformation., PMID:40517442

T-Cell Redirecting Strategies in Large B-Cell Lymphoma and Follicular Lymphoma., PMID:40517438

A Phase 2 Study of Obinutuzumab Combined with Lenalidomide in Previously Untreated High Tumor Burden Follicular Lymphoma., PMID:40517417

Cas9- and Cas12a-mediated excision and replacement of the celiac disease-related α-gliadin immunogenic complex in hexaploid wheat., PMID:40517395

Investigation of the Efficacy and Safety of Xeligekimab (GR1501) in Patients with Moderate-to-Severe Plaque Psoriasis: A Multicenter, Randomized, Double-Blind Phase II Clinical., PMID:40517362

Assessment of Lyme Seroconversion Among US Military Personnel in Honduras., PMID:40517326

Therapeutic Effect of Galactosyltransferase- and Sialyltransferase-encoding mRNA in Rheumatoid Arthritis., PMID:40517291

Positive coactivator PC4 shows dynamic nucleolar distribution required for rDNA transcription and protein synthesis., PMID:40517275

Quantitative response assessment of combined immunotherapy in a murine melanoma model using multiparametric MRI., PMID:40517176

Doubling multiplexed imaging capability via spatial expression pattern-guided protein pairing and computational unmixing., PMID:40517167

Advances in molecular pathology and therapy of non-small cell lung cancer., PMID:40517166

Enhanced visualization of colonic polyps using a fluorophore-conjugated claudin-1 antibody in a CPC-APC mouse model., PMID:40517099

Evaluating the Role of CAR-T Cell Therapy in the Context of Current Therapy Options for Patients With Relapsed or Refractory Follicular Lymphoma., PMID:40516919

The Role of Tumor Microenvironment and Immune Cell Crosstalk in Triple-Negative Breast Cancer (TNBC): Emerging Therapeutic Opportunities., PMID:40516902

Potential blocker of SARS-CoV entry and a narrow functionality of its spike protein motifs on Qubevirus platform., PMID:40516871

Nanobodies targeting EGFR provide insight into conformations stabilized by glioblastoma mutations., PMID:40516870

A pooled analysis of datopotamab deruxtecan in patients with EGFR-mutated NSCLC., PMID:40516821

Genomic profiles of pathogenic and moderate-penetrance germline variants associated with risk of early-onset lung adenocarcinoma., PMID:40516820

Decreased pathogenicity of triple-mutant of Aeromonas hydrophila flgK, flgL, flgE suggests its potential as a live attenuated vaccine for Carassius auratus., PMID:40516799

Current and emerging strategies for subcutaneous delivery of high-concentration and high-dose antibody therapeutics., PMID:40516697

Efficacy of waitlist desensitization for lung candidates is limited by antibody rebound., PMID:40516662

Analytical Comparison of Commonly Used Laboratory-Developed Tests for the Assessment of Ki-67 in Breast Carcinoma With an FDA-Approved Benchmark., PMID:40516608

WAYPOINT: Are we there yet for patients with nasal polyposis?, PMID:40516522

Modular high-throughput platform for the purification of scFvs and multispecific antibody-based therapeutics., PMID:40516489

Evaluation of commercial vaccines for efficacy and transmission control against the emergent H5N8 (clade 2.3.4.4b) avian influenza virus in Kazakhstan., PMID:40516487

CD38-targeted antibody-polymer drug conjugates for enhanced treatment of multiple myeloma., PMID:40516447

Fixed dosing versus weight-based dosing of HIV-1 prophylactic monoclonal antibodies in adults: a post-hoc, cross-protocol pharmacokinetics modelling study., PMID:40516378

Identification of candidate vaccine antigens using 2-D gel electrophoresis and immunoproteomics for cross protection against Glaesserella parasuis., PMID:40516376

A fc-engineered NKG2D × B7-H3 bispecific antibody enhances the antitumor activity by orchestrating cytotoxic lymphocytes., PMID:40516256

Diagnostic significance of carcinoembryonic antigen and anti-MDA5 antibodies in polymyositis/dermatomyositis-associated rapidly progressive interstitial lung disease., PMID:40516211

Combined use of Carfilzomib and plasmapheresis in antibody-mediated liver transplant rejection., PMID:40516200

Trop-2 expression as a biomarker of response to sacituzumab govitecan in patients with HER2-negative metastatic breast cancer: A pilot study., PMID:40516178

Cost-Effectiveness Analysis of Universal Screening for Subclinical Hypothyroidism in Pregnancy Based on the Czech Nation-Wide Pilot Screening Program in Light of Current Evidence., PMID:40516156

Common Toll-like receptor 7 variants define disease risk and phenotypes in juvenile-onset systemic lupus erythematosus., PMID:40516124

Transplants foster B cell alloimmunity by relaying extracellular vesicles to follicular dendritic cells., PMID:40516053

Transient glycan shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques., PMID:40516049

m6A-REFII: an antibody-independent tool for in situ visualizing cellular specific RNA m6A compatible with protein immunofluorescence staining., PMID:40516020

The immune response of Boschveld chickens to a Newcastle disease vaccination program designed for commercial layers., PMID:40515962

Prevalence and clinical significance of autoantibodies to sulphite oxidase and glycogen phosphorylase in Chinese primary biliary cholangitis patients., PMID:40515960

RNA-Binding Protein Immunoprecipitation 1 (RIP) Assay to Investigate the Interactions Between Viral RNA and Host Proteins., PMID:40515923

Determination of Protein Ubiquitination After Protein Denaturation in Virus-Host Interactions., PMID:40515897

Beyond BCL2 (B cell lymphoma) and BTK (Bruton tyrosine kinase) inhibitors: novel agents and resistance mechanisms for chronic lymphocytic leukemia., PMID:40515863

Response to telitacicept in optic neuritis associated with Sjogren's syndrome: a case report and literature review., PMID:40515854

Basal cell adenoma with S100 protein-positive "stroma": a distinct triphasic salivary gland neoplasm characterized by CTNNB1 mutation., PMID:40515848

Effectiveness and safety of ravulizumab for Japanese patients with atypical hemolytic uremic syndrome switched from eculizumab: an analysis of a post-marketing surveillance., PMID:40515788

The Immunology of Alpha-Gal Syndrome: History, Tick Bites, IgE, and Delayed Anaphylaxis to Mammalian Meat., PMID:40515672

A comparison of JC virus assay performance provided with originator and biosimilar natalizumab., PMID:40515643

Beyond the switch to the biosimilar of natalizumab: What is the impact of changing the JCV test?, PMID:40515642

Diagnostic uncertainty in the era of biosimilar natalizumab-The case for harmonizing anti-JCV antibody testing., PMID:40515640

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

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For research use only. Not for human or drug use.

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Anti-RAPGEF3/EPAC 1 Antibody (R1G47) [RHB63702]
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