Catalog No.
YHC23301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asn352
Predicted molecular weight
42.41 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07196
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NEFL, Neurofilament light polypeptide, 68 kDa neurofilament protein, NF68, Neurofilament triplet L protein, NF-L, NFL
Annual level changes of serum neuronal and glial biomarkers in a German professional football club., PMID:40514556
Blood Biomarkers of Neurodegeneration over Four Decades After Toxic Oil Syndrome: A Case-Control Study., PMID:40507935
Evaluating Glial Fibrillary Acidic Protein and Neurofilament Light as Potential Biomarkers for Spinocerebellar Ataxia 7., PMID:40507882
Presynaptic loss and axonal degeneration synergistically correlate with longitudinal neurodegeneration and cognitive decline., PMID:40495607
Chitinase-3-Like 1 Protein (CHI3L1) Levels in Patients With Cognitive Deficits and Movement Disorders: Comparison With Other Biomarkers., PMID:40495463
Plasma biomarkers for early detection of alzheimer's disease: a cross-sectional study in a Japanese cohort., PMID:40483474
Plasma and MRI biomarkers capture neuronal damage in former professional boxers., PMID:40481074
Serum Neurofilament Light Chain as a Biomarker for CIDP Diagnosis, Severity, and Treatment Outcome., PMID:40472292
Comparative Analysis of SiMoA and Ella Immunoassay Platforms for Measuring Serum Neurofilament Light Chain Levels in ATTRv With Polyneuropathy and Presymptomatic Carriers., PMID:40462552
Synaptic markers are associated with cognitive decline after accounting for amyloid burden among an at-risk Alzheimer's disease cohort., PMID:40461705
Inverse relation between serum neurofilament light chain and cognitive function in chronic inflammatory demyelinating polyneuropathy., PMID:40459587
Value of biomarkers in the prediction of shunt responsivity in patients with normal pressure hydrocephalus., PMID:40457021
Association of Peak Width of Skeletonized Mean Diffusivity With Neurofilament Light Chain in Non-Dementia Adults., PMID:40420623
Blood biomarkers of Alzheimer's disease and 12-year muscle strength trajectories in community-dwelling older adults: a cohort study., PMID:40414227
Associations among blood heavy metals, neurofilament light chains and cognition function in US adults: NHANES 2013-2014., PMID:40412247
Extracellular Vesicle Glial Fibrillary Acidic Protein as a Circulating Biomarker of Traumatic Brain Injury Severity., PMID:40410624
Glial Fibrillary Acid Protein Reflects Disease Activity in Autoimmune Encephalitis., PMID:40407316
Serum GFAP and NfL levels in migraine: A registry for migraine (REFORM) study., PMID:40405682
Neuroimaging and plasma biomarker differences and commonalities in Lewy body dementia subtypes., PMID:40403153
Biomarker discovery in Alzheimer's and neurodegenerative diseases using Nucleic Acid Linked Immuno-Sandwich Assay., PMID:40401628
Physical and biopsychosocial frailty, cognitive phenotypes, and plasma biomarkers for Alzheimer's disease in Chinese older adults: A population-based study., PMID:40399764
Associations between sleep quality, plasma neurofilament light, and cognition in older adults without dementia., PMID:40379641
Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study., PMID:40373252
The role of serum neurofilament light (sNfL) as a biomarker in multiple sclerosis: insights from a systematic review., PMID:40372550
Sex-specific associations of the endocrine-disrupting chemicals with serum neurofilament light chain among US adults., PMID:40367613
Tyrosine kinase inhibitor, masitinib, limits neuronal damage, as measured by serum neurofilament light chain concentration in a model of neuroimmune-driven neurodegenerative disease., PMID:40367050
Serum glial fibrillary protein reflects early brain injury dynamics and cognitive changes after deep brain stimulation surgery., PMID:40360583
Plasma concentrations of neurofilament light, p-Tau231 and glial fibrillary acidic protein are elevated in patients with chronic kidney disease and correlate with measured glomerular filtration rate., PMID:40346521
Cerebral Amyloid Angiopathy and Downstream Alzheimer Disease Plasma Biomarkers., PMID:40343697
APOE4, Blood Neurodegenerative Biomarkers, and Cognitive Decline in Community-Dwelling Older Adults., PMID:40332937
Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients., PMID:40330487
Plasma biomarkers as core mediators in functional network abnormalities: Evidence from a two-cohort study., PMID:40329658
Cerebrospinal fluid biomarkers of efficacy in patients affected by spinal muscular atrophy type 1 treated with nusinersen., PMID:40317413
Profiling 92 circulating neurobiological proteins identifies novel candidate biomarkers of long-term cognitive outcome after ischemic stroke., PMID:40316737
Neurofilament Light Chain Correlates with Stroke Severity and Clinical Outcome in Acute Cerebrovascular Stroke Patients., PMID:40304765
Extracellular Vesicle Marker Changes Associated With Disease Activity in Relapsing-Remitting Multiple Sclerosis., PMID:40300121
Sex differences in the clinical manifestation of autosomal dominant frontotemporal dementia., PMID:40277077
Relationships between blood pressure indicators and fluid biomarkers of brain aging in functionally intact older adults., PMID:40259431
Association of serum neurofilament light chain and bone mineral density in adults., PMID:40259260
Correlation of extracellular vesicle Alu RNA with brain aging and neuronal injury: a potential biomarker for brain aging., PMID:40248949
Do Nitrosative Stress Molecules Hold Promise as Biomarkers for Multiple Sclerosis?, PMID:40244291
Association of Nonmodifiable Risk Factors With Alzheimer Disease Blood Biomarkers in Community-Dwelling Adults in the ESTHER Study., PMID:40239154
Elevated serum concentrations of GFAP in hereditary transthyretin amyloidosis since pre-symptomatic stages., PMID:40232501
The utility of serum neurofilament light chain in MOGAD: Current insights and future directions., PMID:40220725
Cognitive reserve in young-onset cognitive impairment., PMID:40220626
Blood-based biomarkers for Alzheimer's disease in Down syndrome: A systematic review and meta-analysis., PMID:40219863
Serum protein biomarkers for degenerative cervical myelopathy: a prospective study., PMID:40215624
Kinetics of serum NFL and GFAP and changes in cognitive functions, in MS patients treated with repeated administrations of autologous mesenchymal stem cells (MSC-NG01)., PMID:40215559
The relationship between triglyceride-glucose index and serum neurofilament light chain: Findings from NHANES 2013-2014., PMID:40208889
Neurofilament light chain as a marker for neuronal damage: integrating in vitro studies and clinical findings in patients with oxaliplatin-induced neuropathy., PMID:40208334
For research use only. Not for human or drug use.
