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Anti-RAMP1 Antibody (R1E91)

Catalog #:   RHB03601 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: WB
Accession: O60894
Overview

Catalog No.

RHB03601

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

WB: 1:500-1:1000

Target

RAMP1, Receptor activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1, CRLR activity-modifying protein 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O60894

Applications

WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1E91

Data Image
  • Western blot
    Western blot analysis of RAMP1 in Raji, COS7, C6, 3T3, Hela lysates using RAMP1 antibody.
References

Receptor activity-modifying protein modulation of parathyroid hormone-1 receptor function and signaling., PMID:39376604

Neuroimmune modulating and energy supporting nanozyme-mimic scaffold synergistically promotes axon regeneration after spinal cord injury., PMID:38970101

Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein., PMID:38603770

Characteristics associated with response to subcutaneously administered anti-CGRP monoclonal antibody medications in a real-world community cohort of persons living with migraine: A retrospective clinical and genetic study., PMID:38071464

The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats., PMID:37686275

Pharmacological characterisation of erenumab, Aimovig, at two calcitonin gene-related peptide responsive receptors., PMID:37580864

Response to erenumab assessed by Headache Impact Test-6 is modulated by genetic factors and arterial hypertension: An explorative cohort study., PMID:36627267

Gel-forming antagonist provides a lasting effect on CGRP-induced vasodilation., PMID:36569288

Characterization of Antibodies against Receptor Activity-Modifying Protein 1 (RAMP1): A Cautionary Tale., PMID:36555690

Procalcitonin mediates vascular dysfunction in obesity., PMID:35998685

Characterization of transit rates in the large intestine of mice following treatment with a CGRP antibody, CGRP receptor antibody, and small molecule CGRP receptor antagonists., PMID:35822594

Virtual drug repurposing study for the CGRPR identifies pentagastrin and leuprorelin as putative candidates., PMID:35803082

CGRP and the Calcitonin Receptor are Co-Expressed in Mouse, Rat and Human Trigeminal Ganglia Neurons., PMID:35620595

Characterization of erenumab and rimegepant on calcitonin gene-related peptide induced responses in Xenopus Laevis oocytes expressing the calcitonin gene-related peptide receptor and the amylin-1 receptor., PMID:35614383

The PACAP pathway is independent of CGRP in mouse models of migraine: possible new drug target?, PMID:35136961

Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice., PMID:35115501

IMD/ADM2 operates as a secretory factor that controls cumulus-oocyte complexes (COCs) conformation for oocytes in vitro maturation., PMID:35102467

Clinic and genetic predictors in response to erenumab., PMID:34965002

Modulation of osteoclastogenesis through adrenomedullin receptors on osteoclast precursors: initiation of differentiation by asymmetric cell division., PMID:34611305

CGRP-dependent signalling pathways involved in mouse models of GTN- cilostazol- and levcromakalim-induced migraine., PMID:34407650

CGRP receptor antagonists for migraine. Are they also AMY1 receptor antagonists?, PMID:34076887

Targeting Adrenomedullin in Oncology: A Feasible Strategy With Potential as Much More Than an Alternative Anti-Angiogenic Therapy., PMID:33489885

The Effects of Calcitonin Gene-Related Peptide on Bone Homeostasis and Regeneration., PMID:33030684

Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion., PMID:32086679

Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab)., PMID:32049005

C-fibers may modulate adjacent Aδ-fibers through axon-axon CGRP signaling at nodes of Ranvier in the trigeminal system., PMID:31718551

Sex differences in the expression of calcitonin gene-related peptide receptor components in the spinal trigeminal nucleus., PMID:31223141

Development of chimeric and bifunctional antagonists for CLR/RAMP receptors., PMID:31150417

Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma., PMID:30741933

Calcitonin Gene-Related Peptide Antagonists and Therapeutic Antibodies., PMID:30689083

CGRP Antibodies as Prophylaxis in Migraine., PMID:30550780

The Role of Calcitonin Gene Related Peptide (CGRP) in Neurogenic Vasodilation and Its Cardioprotective Effects., PMID:30283343

Neuropeptide regulation of adaptive immunity in the tibia fracture model of complex regional pain syndrome., PMID:29642930

Is the activity of CGRP and Adrenomedullin regulated by RAMP (-2) and (-3) in Trypanosomatidae? An in-silico approach., PMID:29626675

Increased receptor activity-modifying protein 1 in the nervous system is sufficient to protect against autonomic dysregulation and hypertension., PMID:29297736

Recognizing the role of CGRP and CGRP receptors in migraine and its treatment., PMID:29020807

Distribution of CGRP and its receptor components CLR and RAMP1 in the rat retina., PMID:28603014

The Trigeminovascular Pathway: Role of CGRP and CGRP Receptors in Migraine., PMID:28485848

Glucocorticoid Receptor ChIP-Seq Identifies PLCD1 as a KLF15 Target that Represses Airway Smooth Muscle Hypertrophy., PMID:28375666

Induction of Migraine-Like Photophobic Behavior in Mice by Both Peripheral and Central CGRP Mechanisms., PMID:28053042

Immunohistochemical localization of the calcitonin gene-related peptide binding site in the primate trigeminovascular system using functional antagonist antibodies., PMID:27155150

Mapping the calcitonin receptor in human brain stem., PMID:26911465

Localization of CGRP receptor components and receptor binding sites in rhesus monkey brainstem: A detailed study using in situ hybridization, immunofluorescence, and autoradiography., PMID:26105175

CGRP as a neuropeptide in migraine: lessons from mice., PMID:26032833

Role of receptor activity modifying protein 1 in function of the calcium sensing receptor in the human TT thyroid carcinoma cell line., PMID:24454825

Changes in calcitonin gene-related peptide (CGRP) receptor component and nitric oxide receptor (sGC) immunoreactivity in rat trigeminal ganglion following glyceroltrinitrate pretreatment., PMID:24004534

CGRP receptor antagonism and migraine therapy., PMID:23745702

CCL17/thymus and activation-regulated chemokine induces calcitonin gene-related peptide in human airway epithelial cells through CCR4., PMID:23731651

Novel pathways in the pathobiology of human abdominal aortic aneurysms., PMID:22797469

Intermedin stabilized endothelial barrier function and attenuated ventilator-induced lung injury in mice., PMID:22563471

Datasheet

Document Download

Anti-RAMP1 Antibody (R1E91).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-RAMP1 Antibody (R1E91) [RHB03601]
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