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Anti-TBC1D4 Antibody (R1E54)

Catalog #:   RHA89001 Specific References (15) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IP, WB
Accession: O60343
Overview

Catalog No.

RHA89001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IP: 1:20, WB: 1:500-1:1000

Target

KIAA0603, TBC1D4, Akt substrate of 160 kDa, AS160, TBC1 domain family member 4

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O60343

Applications

IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1E54

Data Image
  • Western blot
    Western blot analysis of AS160 in 293 lysates using AS160 antibody.
References

Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects., PMID:23344726

Immunofluorescent localization of the Rab-GAP protein TBC1D4 (AS160) in mouse kidney., PMID:22466139

Thr649Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle., PMID:22318952

Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion., PMID:22139838

Negative regulation of adiponectin secretion by receptor interacting protein 140 (RIP140)., PMID:21872658

In vivo exercise followed by in vitro contraction additively elevates subsequent insulin-stimulated glucose transport by rat skeletal muscle., PMID:20179245

Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle., PMID:19923418

Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle., PMID:19252894

Inhibition of contraction-stimulated AMP-activated protein kinase inhibits contraction-stimulated increases in PAS-TBC1D1 and glucose transport without altering PAS-AS160 in rat skeletal muscle., PMID:19208911

Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during postexercise recovery., PMID:18845784

Contraction-stimulated glucose transport in rat skeletal muscle is sustained despite reversal of increased PAS-phosphorylation of AS160 and TBC1D1., PMID:18818383

Globular adiponectin stimulates glucose transport in type 2 diabetic muscle., PMID:18615850

Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle., PMID:18276596

Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes., PMID:18215134

Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle., PMID:16731842

Datasheet

Document Download

Anti-TBC1D4 Antibody (R1E54).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-TBC1D4 Antibody (R1E54) [RHA89001]
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