Catalog No.
RHA84101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, WB: 1:500-1:1000
Target
BNIP3H, BNIP3A, NIP3-like protein X, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, NIP3L, Adenovirus E1B19K-binding protein B5, NIX, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like, BNIP3L
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O60238
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1E46
Autophagy and mitophagy-related extracellular mitochondrial dysfunction of cerebrospinal fluid cells in patients with hemorrhagic moyamoya disease., PMID:37612316
BNIP3L/NIX-mediated mitophagy alleviates passive stress-coping behaviors induced by tumor necrosis factor-α., PMID:36914810
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes., PMID:33404293
BNIP3L Is a New Autophagy Related Prognostic Biomarker for Melanoma Patients Treated With AGI-101H., PMID:32620611
BNIP3L-Dependent Mitophagy Promotes HBx-Induced Cancer Stemness of Hepatocellular Carcinoma Cells via Glycolysis Metabolism Reprogramming., PMID:32168902
Adalimumab changes the expression profile of selected BCL-2 family genes., PMID:32068934
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
Proximity Ligation In situ Assay is a Powerful Tool to Monitor Specific ATG Protein Interactions following Autophagy Induction., PMID:26034986
HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC)., PMID:25484075
Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis., PMID:23142642
Delineation of apoptotic genes for synergistic apoptosis of lexatumumab and anthracyclines in human renal cell carcinoma cells by polymerase chain reaction array., PMID:22205156
The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray., PMID:21490427
Placental localization and expression of the cell death factors BNip3 and Nix in preeclampsia, intrauterine growth retardation and HELLP syndrome., PMID:16219518
Blockade of epidermal growth factor receptors chemosensitizes breast cancer cells through up-regulation of Bnip3L., PMID:16166289
BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF., PMID:12879018
The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase., PMID:12606722
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia., PMID:10922063
BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites., PMID:10625696
For research use only. Not for human or drug use.
