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Anti-KLF4 Antibody (R1E08)

Catalog #:   RMA68101 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IHC, IP, WB
Accession: Q60793
Overview

Catalog No.

RMA68101

Species reactivity

Human, Mouse, Hamster

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000

Target

KLF4, Gut-enriched krueppel-like factor, Krueppel-like factor 4, EZF, GKLF, Epithelial zinc finger protein EZF

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q60793

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1E08

Data Image
  • Immunohistochemical
    Immunohistochemistry analysis of paraffin-embedded mouse colon using KLF4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot
    Western blot analysis of KLF4 in Hela, CHO-K1 lysates using KLF4 antibody.
References

Isolation and Culture of Primary Pericytes from Mouse., PMID:40291426

Glomerular mesangial cells derived complement factor H regulates complement activation, influences cell proliferation, and maintains actin cytoskeleton., PMID:40157080

Fusobacterium nucleatum Promotes the Growth and Metastasis of Colorectal Cancer by Activating E-Cadherin/Krüppel-Like Factor 4/Integrin α5 Signaling in a Calcium-Dependent Manner., PMID:40066228

Amelioration of LPS-Induced Jejunum Injury and Mucus Barrier Damage in Mice by IgY Embedded in W/O/W Emulsion., PMID:39767078

Endothelial γ-protocadherins inhibit KLF2 and KLF4 to promote atherosclerosis., PMID:39232138

Transglutaminase 2 Regulates HSF1 Gene Expression in the Acute Phase of Fish Optic Nerve Regeneration., PMID:39201764

Targeting the Depletion of M2 Macrophages: Implication in Cancer Immunotherapy., PMID:38989738

Reprogramming of astrocytes to neuronal-like cells in spinal cord injury: a systematic review., PMID:38448665

Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy., PMID:37004094

Exploring the reprogramming potential of B cells and comprehending its clinical and therapeutic perspective., PMID:36921730

Endothelial Cell Markers Are Inferior to Vascular Smooth Muscle Cells Markers in Staining Vasa Vasorum and Are Non-Specific for Distinct Endothelial Cell Lineages in Clinical Samples., PMID:36768296

The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis., PMID:36003376

Eucalyptol prevents bleomycin-induced pulmonary fibrosis and M2 macrophage polarization., PMID:35964659

RNA Sequencing Reveals Beneficial Effects of Atorvastatin on Endothelial Cells in Acute Kawasaki Disease., PMID:35861833

Inhibitory Effect of Essential Oil From Fructus of Alpinia zerumbet on Endothelial-to-Mesenchymal Transformation Induced by TGF-β1 and Downregulation of KLF4., PMID:35794074

Oncofetal proteins and cancer stem cells., PMID:35670043

Iguratimod Attenuates Macrophage Polarization and Antibody-Mediated Rejection After Renal Transplant by Regulating KLF4., PMID:35614941

Tenascin-X Mediates Flow-Induced Suppression of EndMT and Atherosclerosis., PMID:35443807

Modulation of IL-6 Expression by KLF4-Mediated Transactivation and PCAF-Mediated Acetylation in Sublytic C5b-9-Induced Rat Glomerular Mesangial Cells., PMID:35046941

KLF4, negatively regulated by miR-7, suppresses osteoarthritis development via activating TGF-β1 signaling., PMID:34891002

Excellent effects and possible mechanisms of action of a new antibody-drug conjugate against EGFR-positive triple-negative breast cancer., PMID:34879870

Telocytes in the human ascending aorta: Characterization and exosome-related KLF-4/VEGF-A expression., PMID:34562312

Isoalantolactone alleviates ovalbumin‑induced asthmatic inflammation by reducing alternatively activated macrophage and STAT6/PPAR‑γ/KLF4 signals., PMID:34368878

Inflammation in an Animal Model of Multiple Sclerosis Leads to MicroRNA-25-3p Dysregulation Associated with Inhibition of Pten and Klf4., PMID:34134453

Identification of calmodulin-like protein 5 as tumor-suppressor gene silenced during early stage of carcinogenesis in squamous cell carcinoma of uterine cervix., PMID:33997976

Formation of pure nanoparticles with solvent-fractionated lignin polymers and evaluation of their biocompatibility., PMID:33957201

Regorafenib enhances antitumor immunity via inhibition of p38 kinase/Creb1/Klf4 axis in tumor-associated macrophages., PMID:33753566

Actinidia eriantha Polysaccharide and PD1-Antibody Combination Therapy Enhances Antitumor Efficacy in Colorectal Cancer-Xenograft Mice., PMID:33658792

Protein deglycase DJ-1 deficiency induces phenotypic switching in vascular smooth muscle cells and exacerbates atherosclerotic plaque instability., PMID:33501750

Generation of High-Yield, Functional Oligodendrocytes from a c-myc Immortalized Neural Cell Line, Endowed with Staminal Properties., PMID:33498778

Generation of Systemic Lupus Erythematosus Patient-Derived Induced Pluripotent Stem Cells from Blood., PMID:33397195

Transcriptional profiles along cell programming into corneal epithelial differentiation., PMID:33098888

Amniotic fluid mesenchymal stem cells repair mouse corneal cold injury by promoting mRNA N4-acetylcytidine modification and ETV4/JUN/CCND2 signal axis activation., PMID:33010000

BMP6 Regulates Corneal Epithelial Cell Stratification by Coordinating Their Proliferation and Differentiation and Is Upregulated in Pterygium., PMID:32845956

CD47 Promotes Age-Associated Deterioration in Angiogenesis, Blood Flow and Glucose Homeostasis., PMID:32679764

EOFAZ inhibits endothelial‑to‑mesenchymal transition through downregulation of KLF4., PMID:32319539

Targeting cancer stem cell pathways for cancer therapy., PMID:32296030

Characterization of Induced Pluripotent Stem Cells from Human Epidermal Melanocytes by Transduction with Two Combinations of Transcription Factors., PMID:32072883

Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells., PMID:31982829

KLF4 p.A472D Mutation Contributes to Acquired Resistance to Cetuximab in Colorectal Cancer., PMID:31924740

Protein Expression of PTTG-1, OCT-4, and KLF-4 in Seminoma: A Pilot Study., PMID:31572301

Identification of hepatitis B virus and liver cancer bridge molecules based on functional module network., PMID:31543683

Generation of three human induced pluripotent stem cell (hiPSC) lines derived from one Gaucher disease patient with Parkinson's disease and two unrelated Parkinson's disease patients with GBA mutations., PMID:31401455

KLF4 Regulates Corneal Epithelial Cell Cycle Progression by Suppressing Canonical TGF-β Signaling and Upregulating CDK Inhibitors P16 and P27., PMID:30786277

Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice., PMID:30442679

Genome-wide analysis of gene expression after one year of venom immunotherapy., PMID:30312636

Generation of induced pluripotent stem cell line (ZZUi007-A) from a 52-year-old patient with a novel CHCHD2 gene mutation in Parkinson's disease., PMID:30237140

Characterization of induced tissue-specific stem cells from pancreas by a synthetic self-replicative RNA., PMID:30120295

Stemness and Regenerative Potential of Corneal Stromal Stem Cells and Their Secretome After Long-Term Storage: Implications for Ocular Regeneration., PMID:30046814

Kruppel-Like Factor 4 Positively Regulates Autoimmune Arthritis in Mouse Models and Rheumatoid Arthritis in Patients via Modulating Cell Survival and Inflammation Factors of Fibroblast-Like Synoviocyte., PMID:29997611

Datasheet

Document Download

Anti-KLF4 Antibody (R1E08).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-KLF4 Antibody (R1E08) [RMA68101]
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