Catalog No.
RHA49802
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
p53-like transcription factor, Tumor protein p73, P73, p53-related protein, TP73
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O15350
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1D75
TAp73 and ΔTAp73 isoforms show cell-type specific distributions and alterations in cancer., PMID:39622910
Differentially Expressed Genes Involved in Primary Resistance to Immunotherapy in Patients with Advanced-Stage Pulmonary Cancer., PMID:38396726
Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes., PMID:38055913
Immunohistochemical Profile of Tumor Suppressor Proteins RASSF1A and LATS1/2 in Relation to p73 and YAP Expression, of Human Inflammatory Bowel Disease and Normal Intestine., PMID:30604274
[Application of PLA Method for Detection of p53/p63/p73 Complexes in Situ in Tumour Cells and Tumour Tissue]., PMID:28471195
Dehydroleucodine Induces a TP73-dependent Transcriptional Regulation of Multiple Cell Death Target Genes in Human Glioblastoma Cells., PMID:27671304
Depletion of CABYR-a/b sensitizes lung cancer cells to TRAIL-induced apoptosis through YAP/p73-mediated DR5 upregulation., PMID:26843620
Overexpression of the ∆Np73 isoform is associated with centrosome amplification in brain tumor cell lines., PMID:25910708
Relationship between expression of P27, Fragile Histidine Triad (FHT), phosphatase and tensin homolog deleted on chromosome ten (PTEN), P73, and prognosis in esophageal squamous cell carcinoma., PMID:25622532
The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site., PMID:25510918
Alterations of p63 and p73 in human cancers., PMID:25201187
Involvement of miR-196a in HIV-associated neurocognitive disorders., PMID:24872081
Gene expression profiling upon (212) Pb-TCMC-trastuzumab treatment in the LS-174T i.p. xenograft model., PMID:24403230
Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters., PMID:24006445
Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells., PMID:23887605
Characterization of specific p63 and p63-N-terminal isoform antibodies and their application for immunohistochemistry., PMID:23887585
Proinflammatory cytokines and bile acids upregulate ΔNp73 protein, an inhibitor of p53 and p73 tumor suppressors., PMID:23717592
Intracellular distribution of the ΔNp73 protein isoform in medulloblastoma cells: a study with newly generated rabbit polyclonal antibodies., PMID:23338942
Dissection of cell context-dependent interactions between HBx and p53 family members in regulation of apoptosis: a role for HBV-induced HCC., PMID:22030623
Expression of p63 and p73 in acoustic neuroma and its possible clinical relevance., PMID:22000483
Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs., PMID:21508668
Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph., PMID:21048031
TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status., PMID:20146801
P634A4 and TAp73 immunocytochemistry in liquid-based cervical cytology--potential biomarkers for diagnosis and progress prediction of cervical neoplasia., PMID:20081800
An essential role for p73 in regulating mitotic cell death., PMID:20010785
Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway., PMID:19965642
Evaluation of p63 and p73 antibodies for cross-reactivity., PMID:19855172
Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas., PMID:19541929
Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM., PMID:19541822
PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells., PMID:19421143
Interaction of Helicobacter pylori with gastric epithelial cells is mediated by the p53 protein family., PMID:18343378
Yin Yang 1 induces transcriptional activity of p73 through cooperation with E2F1., PMID:17980704
p73 expression in medulloblastoma: TAp73/DeltaNp73 transcript detection and possible association of p73alpha/DeltaNp73 immunoreactivity with survival., PMID:17912537
Transcriptional regulation of the p73 gene, a member of the p53 family, by early growth response-1 (Egr-1)., PMID:17822668
Detection of antibodies against p63 and p73 isoforms in sera from patients diagnosed with oral lichen planus., PMID:17238971
Multiple isoforms of the tumor protein p73 are expressed in the adult human telencephalon and choroid plexus and present in the cerebrospinal fluid., PMID:16630058
DNA methylation in anal intraepithelial lesions and anal squamous cell carcinoma., PMID:16166431
Comparison of p63 and p73 expression in benign and malignant salivary gland lesions., PMID:16021638
Expression of the p53 family of proteins in central and peripheral human corneal endothelial cells., PMID:15889017
New antibodies recognizing p73: comparison with commercial antibodies., PMID:15781249
p73 is a p53-independent, Sp1-dependent repressor of cyclin B1 transcription., PMID:15737644
The C terminus of p53 family proteins is a cell fate determinant., PMID:15713654
p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2., PMID:15601819
Multiple stress signals induce p73beta accumulation., PMID:15548364
Direct binding of apoptosis signal-regulating kinase 1 to retinoblastoma protein: novel links between apoptotic signaling and cell cycle machinery., PMID:15210709
Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling., PMID:14688019
Differential expression of p73alpha in normal ectocervical epithelium, cervical intraepithelial neoplasia, and invasive squamous cell carcinoma., PMID:14501821
p73 Overexpression and angiogenesis in human colorectal carcinoma., PMID:12865464
Synergistic decline in expressions of p73 and p21 with invasion in esophageal cancers., PMID:12841870
Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73., PMID:12676926
For research use only. Not for human or drug use.
