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Anti-TP73 Antibody (R1D75)

Catalog #:   RHA49802 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, WB
Accession: O15350
Overview

Catalog No.

RHA49802

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

p53-like transcription factor, Tumor protein p73, P73, p53-related protein, TP73

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O15350

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1D75

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded rat brain, using p73 Antibody.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
  • Western blot
    Western blot analysis of p73 expression in HeLa cell lysate.
References

TAp73 and ΔTAp73 isoforms show cell-type specific distributions and alterations in cancer., PMID:39622910

Differentially Expressed Genes Involved in Primary Resistance to Immunotherapy in Patients with Advanced-Stage Pulmonary Cancer., PMID:38396726

Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes., PMID:38055913

Immunohistochemical Profile of Tumor Suppressor Proteins RASSF1A and LATS1/2 in Relation to p73 and YAP Expression, of Human Inflammatory Bowel Disease and Normal Intestine., PMID:30604274

[Application of PLA Method for Detection of p53/p63/p73 Complexes in Situ in Tumour Cells and Tumour Tissue]., PMID:28471195

Dehydroleucodine Induces a TP73-dependent Transcriptional Regulation of Multiple Cell Death Target Genes in Human Glioblastoma Cells., PMID:27671304

Depletion of CABYR-a/b sensitizes lung cancer cells to TRAIL-induced apoptosis through YAP/p73-mediated DR5 upregulation., PMID:26843620

Overexpression of the ∆Np73 isoform is associated with centrosome amplification in brain tumor cell lines., PMID:25910708

Relationship between expression of P27, Fragile Histidine Triad (FHT), phosphatase and tensin homolog deleted on chromosome ten (PTEN), P73, and prognosis in esophageal squamous cell carcinoma., PMID:25622532

The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site., PMID:25510918

Alterations of p63 and p73 in human cancers., PMID:25201187

Involvement of miR-196a in HIV-associated neurocognitive disorders., PMID:24872081

Gene expression profiling upon (212) Pb-TCMC-trastuzumab treatment in the LS-174T i.p. xenograft model., PMID:24403230

Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters., PMID:24006445

Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells., PMID:23887605

Characterization of specific p63 and p63-N-terminal isoform antibodies and their application for immunohistochemistry., PMID:23887585

Proinflammatory cytokines and bile acids upregulate ΔNp73 protein, an inhibitor of p53 and p73 tumor suppressors., PMID:23717592

Intracellular distribution of the ΔNp73 protein isoform in medulloblastoma cells: a study with newly generated rabbit polyclonal antibodies., PMID:23338942

Dissection of cell context-dependent interactions between HBx and p53 family members in regulation of apoptosis: a role for HBV-induced HCC., PMID:22030623

Expression of p63 and p73 in acoustic neuroma and its possible clinical relevance., PMID:22000483

Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs., PMID:21508668

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph., PMID:21048031

TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status., PMID:20146801

P634A4 and TAp73 immunocytochemistry in liquid-based cervical cytology--potential biomarkers for diagnosis and progress prediction of cervical neoplasia., PMID:20081800

An essential role for p73 in regulating mitotic cell death., PMID:20010785

Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway., PMID:19965642

Evaluation of p63 and p73 antibodies for cross-reactivity., PMID:19855172

Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas., PMID:19541929

Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM., PMID:19541822

PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells., PMID:19421143

Interaction of Helicobacter pylori with gastric epithelial cells is mediated by the p53 protein family., PMID:18343378

Yin Yang 1 induces transcriptional activity of p73 through cooperation with E2F1., PMID:17980704

p73 expression in medulloblastoma: TAp73/DeltaNp73 transcript detection and possible association of p73alpha/DeltaNp73 immunoreactivity with survival., PMID:17912537

Transcriptional regulation of the p73 gene, a member of the p53 family, by early growth response-1 (Egr-1)., PMID:17822668

Detection of antibodies against p63 and p73 isoforms in sera from patients diagnosed with oral lichen planus., PMID:17238971

Multiple isoforms of the tumor protein p73 are expressed in the adult human telencephalon and choroid plexus and present in the cerebrospinal fluid., PMID:16630058

DNA methylation in anal intraepithelial lesions and anal squamous cell carcinoma., PMID:16166431

Comparison of p63 and p73 expression in benign and malignant salivary gland lesions., PMID:16021638

Expression of the p53 family of proteins in central and peripheral human corneal endothelial cells., PMID:15889017

New antibodies recognizing p73: comparison with commercial antibodies., PMID:15781249

p73 is a p53-independent, Sp1-dependent repressor of cyclin B1 transcription., PMID:15737644

The C terminus of p53 family proteins is a cell fate determinant., PMID:15713654

p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2., PMID:15601819

Multiple stress signals induce p73beta accumulation., PMID:15548364

Direct binding of apoptosis signal-regulating kinase 1 to retinoblastoma protein: novel links between apoptotic signaling and cell cycle machinery., PMID:15210709

Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling., PMID:14688019

Differential expression of p73alpha in normal ectocervical epithelium, cervical intraepithelial neoplasia, and invasive squamous cell carcinoma., PMID:14501821

p73 Overexpression and angiogenesis in human colorectal carcinoma., PMID:12865464

Synergistic decline in expressions of p73 and p21 with invasion in esophageal cancers., PMID:12841870

Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73., PMID:12676926

Datasheet

Document Download

Anti-TP73 Antibody (R1D75).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-TP73 Antibody (R1D75) [RHA49802]
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