Catalog No.
RHA39601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000
Target
Circadian clock protein PERIOD 2, KIAA0347, Period circadian protein homolog 2, PER2, hPER2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O15055
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1D46
Chronological Effects of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer., PMID:39777632
Prokineticin 2 protein is diurnally expressed in PER2-containing clock neurons in the mouse suprachiasmatic nucleus., PMID:39755259
Period circadian clock 3 is crucial for regulation of IL-22-producing type 3 innate lymphoid cells by flavonoids from Shen Ling Bai Zhu San to alleviate colitis., PMID:39672410
Effect of Urolithin A on the Improvement of Circadian Rhythm Dysregulation in Intestinal Barrier Induced by Inflammation., PMID:39064706
Circadian clock disruption in autoimmune thyroiditis., PMID:37548297
Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis., PMID:35172136
Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons., PMID:35046033
The expression, localisation and interactome of pigeon CRY2., PMID:34645873
Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells., PMID:32597148
Time-restricted feeding in rest phase alters IgE/mast cell-mediated allergic reaction in mice., PMID:31623974
Author Correction: Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing., PMID:30808996
Carbon monoxide protects the kidney through the central circadian clock and CD39., PMID:29463714
Circadian PER2 protein oscillations do not persist in cycloheximide-treated mouse embryonic fibroblasts in culture., PMID:29283306
Long-term Levodopa Treatment Accelerates the Circadian Rhythm Dysfunction in a 6-hydroxydopamine Rat Model of Parkinson's Disease., PMID:28469105
Cyclic Variation of Cellular Clock Proteins in the Mouse Estrous Ovary., PMID:27920997
Interactive Organization of the Circadian Core Regulators PER2, BMAL1, CLOCK and PML., PMID:27383066
Persistent neuronal Ube3a expression in the suprachiasmatic nucleus of Angelman syndrome model mice., PMID:27306933
Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing., PMID:27088856
Twist1 Is a TNF-Inducible Inhibitor of Clock Mediated Activation of Period Genes., PMID:26361389
Hypothalamic expression and moonlight-independent changes of Cry3 and Per4 implicate their roles in lunar clock oscillators of the lunar-responsive Goldlined spinefoot., PMID:25272159
Epigenetic suppression of mouse Per2 expression in the suprachiasmatic nucleus by the inhalational anesthetic, sevoflurane., PMID:24498074
Nucleolar localization and circadian regulation of Per2S, a novel splicing variant of the Period 2 gene., PMID:24202686
Circadian regulation of allergic reactions by the mast cell clock in mice., PMID:24060274
Egr1 regulates lithium-induced transcription of the Period 2 (PER2) gene., PMID:23816566
Antibodies for assessing circadian clock proteins in the rodent suprachiasmatic nucleus., PMID:22558277
Alteration of the circadian clock in children with Smith-Magenis syndrome., PMID:22162479
Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutaneous anaphylactic reaction., PMID:21458659
Casein kinase 1-dependent phosphorylation of familial advanced sleep phase syndrome-associated residues controls PERIOD 2 stability., PMID:21324900
A circadian clock in murine bone marrow-derived mast cells modulates IgE-dependent activation in vitro., PMID:20854894
The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulator., PMID:17260955
Identification of clock as a mechanosensitive gene by large-scale DNA microarray analysis: downregulation in osteoarthritic cartilage., PMID:16767550
The aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin alters the circadian rhythms, quiescence, and expression of clock genes in murine hematopoietic stem and progenitor cells., PMID:16556773
The role of phosphorylation and degradation of hPER protein oscillation in normal human fibroblasts., PMID:14712925
Expression of circadian rhythm genes in gonadotropin-releasing hormone-secreting GT1-7 neurons., PMID:12960008
Involvement of calcium/calmodulin-dependent protein kinase II in the induction of mPer1., PMID:12692905
Transcriptional activation of the neuronal peripherin-encoding gene depends on a G + C-rich element that binds Sp1 in vitro and in vivo., PMID:7622044