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Anti-PER2 Antibody (R1D46)

Catalog #:   RHA39601 Specific References (36) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: FCM, IF, WB
Accession: O15055
Overview

Catalog No.

RHA39601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000

Target

Circadian clock protein PERIOD 2, KIAA0347, Period circadian protein homolog 2, PER2, hPER2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O15055

Applications

FCM, IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1D46

Data Image
  • Western blot
    All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.
  • Western blot
    Western blot analysis of PER2 expression in HeLa cell lysate.
References

Chronological Effects of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer., PMID:39777632

Prokineticin 2 protein is diurnally expressed in PER2-containing clock neurons in the mouse suprachiasmatic nucleus., PMID:39755259

Period circadian clock 3 is crucial for regulation of IL-22-producing type 3 innate lymphoid cells by flavonoids from Shen Ling Bai Zhu San to alleviate colitis., PMID:39672410

Effect of Urolithin A on the Improvement of Circadian Rhythm Dysregulation in Intestinal Barrier Induced by Inflammation., PMID:39064706

Circadian clock disruption in autoimmune thyroiditis., PMID:37548297

Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis., PMID:35172136

Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons., PMID:35046033

The expression, localisation and interactome of pigeon CRY2., PMID:34645873

Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells., PMID:32597148

Time-restricted feeding in rest phase alters IgE/mast cell-mediated allergic reaction in mice., PMID:31623974

Author Correction: Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing., PMID:30808996

Carbon monoxide protects the kidney through the central circadian clock and CD39., PMID:29463714

Circadian PER2 protein oscillations do not persist in cycloheximide-treated mouse embryonic fibroblasts in culture., PMID:29283306

Long-term Levodopa Treatment Accelerates the Circadian Rhythm Dysfunction in a 6-hydroxydopamine Rat Model of Parkinson's Disease., PMID:28469105

Cyclic Variation of Cellular Clock Proteins in the Mouse Estrous Ovary., PMID:27920997

Interactive Organization of the Circadian Core Regulators PER2, BMAL1, CLOCK and PML., PMID:27383066

Persistent neuronal Ube3a expression in the suprachiasmatic nucleus of Angelman syndrome model mice., PMID:27306933

Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing., PMID:27088856

Twist1 Is a TNF-Inducible Inhibitor of Clock Mediated Activation of Period Genes., PMID:26361389

Hypothalamic expression and moonlight-independent changes of Cry3 and Per4 implicate their roles in lunar clock oscillators of the lunar-responsive Goldlined spinefoot., PMID:25272159

Epigenetic suppression of mouse Per2 expression in the suprachiasmatic nucleus by the inhalational anesthetic, sevoflurane., PMID:24498074

Nucleolar localization and circadian regulation of Per2S, a novel splicing variant of the Period 2 gene., PMID:24202686

Circadian regulation of allergic reactions by the mast cell clock in mice., PMID:24060274

Egr1 regulates lithium-induced transcription of the Period 2 (PER2) gene., PMID:23816566

Antibodies for assessing circadian clock proteins in the rodent suprachiasmatic nucleus., PMID:22558277

Alteration of the circadian clock in children with Smith-Magenis syndrome., PMID:22162479

Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutaneous anaphylactic reaction., PMID:21458659

Casein kinase 1-dependent phosphorylation of familial advanced sleep phase syndrome-associated residues controls PERIOD 2 stability., PMID:21324900

A circadian clock in murine bone marrow-derived mast cells modulates IgE-dependent activation in vitro., PMID:20854894

The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulator., PMID:17260955

Identification of clock as a mechanosensitive gene by large-scale DNA microarray analysis: downregulation in osteoarthritic cartilage., PMID:16767550

The aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin alters the circadian rhythms, quiescence, and expression of clock genes in murine hematopoietic stem and progenitor cells., PMID:16556773

The role of phosphorylation and degradation of hPER protein oscillation in normal human fibroblasts., PMID:14712925

Expression of circadian rhythm genes in gonadotropin-releasing hormone-secreting GT1-7 neurons., PMID:12960008

Involvement of calcium/calmodulin-dependent protein kinase II in the induction of mPer1., PMID:12692905

Transcriptional activation of the neuronal peripherin-encoding gene depends on a G + C-rich element that binds Sp1 in vitro and in vivo., PMID:7622044

Datasheet

Document Download

Anti-PER2 Antibody (R1D46).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-PER2 Antibody (R1D46) [RHA39601]
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