Catalog No.
RHA28601
Species reactivity
Human, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
NHERF1, Sodium-hydrogen exchanger regulatory factor 1, SLC9A3R1, Solute carrier family 9 isoform A3 regulatory factor 1, NHERF, EBP50, Ezrin-radixin-moesin-binding phosphoprotein 50, Na(+)/H(+) exchange regulatory cofactor NHE-RF1, NHERF-1, Regulatory cofactor of Na(+)/H(+) exchanger
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O14745
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1D25
Fibroblast Growth Factor 23 Neutralizing Antibody Ameliorates Abnormal Renal Phosphate Handling in Sickle Cell Disease Mice., PMID:37972265
MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells., PMID:34965434
Na+/H+ Exchanger Regulatory Factor 1 Mediates the Pathogenesis of Airway Inflammation in a Murine Model of House Dust Mite-Induced Asthma., PMID:33952618
A Critical Role for Na+/H+ Exchanger Regulatory Factor 1 in Modulating FcεRI-Mediated Mast Cell Activation., PMID:33361207
Fibroblast growth factor 23 and phosphate homeostasis., PMID:31335449
ATPR-induced differentiation and G0/G1 phase arrest in acute promyelocytic leukemia by repressing EBP50/NCF1 complex to promote the production of ROS., PMID:31254567
Assembly of Taurine Transporter (Slc6a6) with Na+-H+ Exchanger Regulatory Factor 1 (Slc9a3r1) Improves GABA Transport Activity by Increasing the Maximum Transport Velocity., PMID:29491210
Systematic Proteogenomic Approach To Exploring a Novel Function for NHERF1 in Human Reproductive Disorder: Lessons for Exploring Missing Proteins., PMID:28960081
The CFTR trafficking mutation F508del inhibits the constitutive activity of SLC26A9., PMID:28360110
Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport., PMID:27432882
A molecular switch in the scaffold NHERF1 enables misfolded CFTR to evade the peripheral quality control checkpoint., PMID:25990958
Novel bioactivity of NHERF1 in corneal neovascularization., PMID:22777301
Overexpression of nuclear NHERF1 in advanced colorectal cancer: association with hypoxic microenvironment and tumor invasive phenotype., PMID:22440733
Peritumoral vascular invasion and NHERF1 expression define an immunophenotype of grade 2 invasive breast cancer associated with poor prognosis., PMID:22439624
Identification of EBP50 as a specific biomarker for carcinogens via the analysis of mouse lymphoma cellular proteome., PMID:22434383
Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles., PMID:21427361
NHERF1/EBP50 is a new marker in colorectal cancer., PMID:21170265
Ezrin and EBP50 redistribute apically in rat uterine epithelial cells at the time of implantation and in response to cell contact., PMID:21120533
Ephrin B1 regulates bone marrow stromal cell differentiation and bone formation by influencing TAZ transactivation via complex formation with NHERF1., PMID:19995908
Biological role of NHERF1 protein expression in breast cancer., PMID:19912366
NHERF-1: modulator of glioblastoma cell migration and invasion., PMID:19308292
Localizations of visual cycle components in retinal pigment epithelium., PMID:19180257
Effects of dietary salt on renal Na+ transporter subcellular distribution, abundance, and phosphorylation status., PMID:18653479
Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4., PMID:18559527
Cortical stabilization of beta-catenin contributes to NHERF1/EBP50 tumor suppressor function., PMID:17325659
Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibrosis cells., PMID:16203733
Directed evolution of PDZ variants to generate high-affinity detection reagents., PMID:15820976
Parathyroid hormone treatment induces dissociation of type IIa Na+-P(i) cotransporter-Na+/H+ exchanger regulatory factor-1 complexes., PMID:15788483
Tissue-specific regulation by estrogen of ezrin and ezrin/radixin/moesin-binding protein 50., PMID:14665715
Assembly and trafficking of a multiprotein ROMK (Kir 1.1) channel complex by PDZ interactions., PMID:14604981
Expression of NHERF-1, NHERF-2, PDGFR-alpha, and PDGFR-beta in normal human kidneys and in renal transplant rejection., PMID:12865627
Distinct cell type-specific expression of scaffolding proteins EBP50 and E3KARP: EBP50 is generally expressed with ezrin in specific epithelia, whereas E3KARP is not., PMID:11893083
Na+-H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3., PMID:11731584
Differential renal distribution of NHERF isoforms and their colocalization with NHE3, ezrin, and ROMK., PMID:11121391
The B1 subunit of the H+ATPase is a PDZ domain-binding protein. Colocalization with NHE-RF in renal B-intercalated cells., PMID:10748165
Regulation of the Na/H exchanger regulatory factor in OK cells., PMID:10436398
Basolateral Na(+)/HCO(3)(-) cotransport activity is regulated by the dissociable Na(+)/H(+) exchanger regulatory factor., PMID:10411549
Estrogen receptor regulation of the Na+/H+ exchange regulatory factor., PMID:10385389
NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin., PMID:9748260
An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton., PMID:9677412
Ion exchangers mediating NaCl transport in the proximal tubule., PMID:9261983
Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger., PMID:7738182
For research use only. Not for human or drug use.
