Catalog No.
YHC20601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly90
Predicted molecular weight
12.49 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P06703
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Calcyclin, S100A6, S100 calcium-binding protein A6, Protein S100-A6, Prolactin receptor-associated protein, MLN 4, CACY, PRA, Growth factor-inducible protein 2A9
Human endothelial cells promote a human neural stem cell type B phenotype via Notch signaling., PMID:40447618
Prognostic Value of Blood-Based Protein Biomarkers in Traumatic Brain Injury: A Living Systematic Review and Meta-Analysis., PMID:40432557
Integrated liver-secreted and plasma proteomics identify a predictive model that stratifies MASH., PMID:40250425
S100 Protein Family in Lung Cancer: an Updated Narrative Review., PMID:40166494
Brigatinib activates inflammasomes: Implication for immune-related adverse events., PMID:40122348
Integrative proteomic analysis reveals the potential diagnostic marker and drug target for the Type-2 diabetes mellitus., PMID:39850446
Lactylation modulation identifies key biomarkers and therapeutic targets in KMT2A-rearranged AML., PMID:39789150
FOXF1 promotes ovarian cancer metastasis by facilitating HMGA2-mediated USP30-dependent S100A6 deubiquitination., PMID:39694080
Low serum S100A6 levels are associated RP-ILD risk in anti-MDA5-positive dermatomyositis., PMID:39680260
Spatial transcriptomics analysis identifies therapeutic targets in diffuse high-grade gliomas., PMID:39530009
Icariin ameliorates Coxsackievirus B3-induced viral myocarditis by modulating the S100 calcium binding protein A6/β-catenin/c-Myc signaling pathway., PMID:39522251
Photobiomodulation Modulates Proliferation and Gene Expression Related to Calcium Signaling in Human Osteoblast Cells., PMID:39381787
TMT-Based Quantitative Proteomic Profiling of Human Esophageal Cancer Cells Reveals the Potential Mechanism and Potential Therapeutic Targets Associated With Radioresistance., PMID:39375892
Overexpression of PRDM16 attenuates acute kidney injury progression: genetic and pharmacological approaches., PMID:39309696
Proteomic Heterogeneity of the Extracellular Matrix Identifies Histologic Subtype-Specific Fibroblast in Gastric Cancer., PMID:39305996
Matrix stiffness regulates the protein profile of extracellular vesicles of pancreatic cancer cell lines., PMID:39279557
Comparative analysis of electrophoresis and interferometric optical detection method for molecular weight determination of proteins., PMID:39229532
Comparative proteomic analysis of retinal hypoxia-ischemia in an acute ocular hypertension model using tandem mass tag-based quantitative proteomics., PMID:39216638
Single-cell RNA and T-cell receptor sequencing unveil mycosis fungoides heterogeneity and a possible gene signature., PMID:39169943
Characterization and proteomic analysis of plasma-derived small extracellular vesicles in locally advanced rectal cancer patients., PMID:39162991
Beyond mutations: Accounting for quantitative changes in the analysis of protein evolution., PMID:39021584
S100A6 Regulates nucleus pulposus cell apoptosis via Wnt/β-catenin signaling pathway: an in vitro and in vivo study., PMID:38877413
Involvement of S100A6/S100A11 in T-Cell Immune Regulatory in HCC Revealed by Single Cell RNA-seq., PMID:38766816
S100A6 could not promote the differentiation of Calu-6 lung cancer cell line., PMID:38694326
S100a6 knockdown promotes the differentiation of dental epithelial cells toward the epidermal lineage instead of the odontogenic lineage., PMID:38593315
Schistosoma mansoni infection induces hepatic metallothionein and S100 protein expression alongside metabolic dysfunction in hamsters., PMID:38562583
S100A6 mediated epithelial-mesenchymal transition affects chemosensitivity of colorectal cancer to oxaliplatin., PMID:38521111
Recognition of granulocyte-macrophage colony-stimulating factor by specific S100 proteins., PMID:38484433
Characterization of primary human leptomeningeal cells in 2D culture., PMID:38434413
Do Alarmins Have a Role in Multiple Myeloma?, PMID:38426298
S100A6 drives lymphatic metastasis of liver cancer via activation of the RAGE/NF-kB/VEGF-D pathway., PMID:38350547
Activation of Hypoxia Inducible Factor-1 Alpha-Mediated DNA Methylation Enzymes (DNMT3a and TET2) Under Hypoxic Conditions Regulates S100A6 Transcription to Promote Lung Cancer Cell Growth and Metastasis., PMID:38299557
Genetic insights into associations of multisite chronic pain with common diseases and biomarkers using data from the UK Biobank., PMID:38104003
Multi-omics approaches reveal the molecular mechanisms underlying the interaction between Clonorchis sinensis and mouse liver., PMID:38076459
Revealing the role of necroptosis microenvironment: FCGBP + tumor-associated macrophages drive primary liver cancer differentiation towards cHCC-CCA or iCCA., PMID:38017206
Label-free quantitative proteomics analysis for type 2 diabetes mellitus early diagnostic marker discovery using data-independent acquisition mass spectrometry (DIA-MS)., PMID:38012280
Multi-omics characteristics of tumor-associated macrophages in the tumor microenvironment of gastric cancer and their exploration of immunotherapy potential., PMID:37880233
Interaction of S100A6 Protein with the Four-Helical Cytokines., PMID:37759746
S100A6 is a potential diagnostic and prognostic biomarker for human glioma., PMID:37736555
S100A6: molecular function and biomarker role., PMID:37670392
The S100 calcium-binding protein A6 plays a crucial role in hepatic steatosis by mediating lipophagy., PMID:37655980
Upregulation of S100A6 and its relation with CD34+ cells apoptosis in high-risk myelodysplastic syndromes patients., PMID:37609402
The Role of S100A6 in Human Diseases: Molecular Mechanisms and Therapeutic Potential., PMID:37509175
Metronomic Administration of Topotecan Alone and in Combination with Docetaxel Inhibits Epithelial-mesenchymal Transition in Aggressive Variant Prostate Cancers., PMID:37476073
ALS Variants of Annexin A11's Proline-Rich Domain Impair Its S100A6-Mediated Fibril Dissolution., PMID:37433222
Calcyclin-binding protein contributes to cholangiocarcinoma progression by inhibiting ubiquitination of MCM2., PMID:37305391
S100A6 inhibits MDM2 to suppress breast cancer growth and enhance sensitivity to chemotherapy., PMID:37217945
Apoptotic Cell Death in Bicuspid-Aortic-Valve-Associated Aortopathy., PMID:37108591
Identification of LBH and SPP1 involved in hepatic stellate cell activation during liver fibrogenesis., PMID:36917392
Murine neonatal cardiac B cells promote cardiomyocyte proliferation and heart regeneration., PMID:36774363
For research use only. Not for human or drug use.
