Catalog No.
RHA11401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IP: 1:20, WB: 1:500-1:1000
Target
Insulin-like growth factor 2 mRNA-binding protein 3, VICKZ3, IGF2BP3, IMP3, KH domain-containing protein overexpressed in cancer, IMP-3, VICKZ family member 3, IGF-II mRNA-binding protein 3, KOC1, hKOC, IGF2 mRNA-binding protein 3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O00425
Applications
IF, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1C88
IMP3, CDK4, MDM2 and β-catenin expression in Enchondroma and Central Chondrosarcoma: Diagnostic and prognostic utility., PMID:39368400
METTL16 participates in haemoglobin H disease through m6A modification., PMID:39088431
Lin28a forms an RNA-binding complex with Igf2bp3 to regulate m6A-modified stress response genes in stress granules of muscle stem cells., PMID:39021312
IGF2BP3 Enhances the Growth of Hepatocellular Carcinoma Tumors by Regulating the Properties of Macrophages and CD8+ T Cells in the Tumor Microenvironment., PMID:37719968
IGF2BP3 promotes the progression of colorectal cancer and mediates cetuximab resistance by stabilizing EGFR mRNA in an m6A-dependent manner., PMID:37658049
IGF2BP3/HIF1A/YAP signaling plays a role in driving acute-on-chronic liver failure through activating hepatocyte reprogramming., PMID:37257765
m6A Regulator-mediated RNA Methylation Modulates Immune Microenvironment of Hepatitis B Virus-related Acute Liver Failure., PMID:37256461
The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production., PMID:37141498
Genome-wide association study of the response of patients with diabetic macular edema to intravitreal Anti-VEGF injection., PMID:36581632
m6A methylation regulators as predictors for treatment of advanced urothelial carcinoma with anti-PDL1 agent., PMID:36189296
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation., PMID:34471108
The germinal center reaction depends on RNA methylation and divergent functions of specific methyl readers., PMID:34402854
RNA Demethylase FTO Mediated RNA m6A Modification Is Involved in Maintaining Maternal-Fetal Interface in Spontaneous Abortion., PMID:34350169
c-Met expression in renal cell carcinoma with bone metastases., PMID:33024658
The Oncogenic Functions of Insulin-like Growth Factor 2 mRNA-Binding Protein 3 in Human Carcinomas., PMID:32282295
The complementary role of insulin-like growth factor II mRNA-binding protein 3 (IMP3) in diagnosis of Hodgkin's lymphoma., PMID:31319330
Cancer-testis antigens as biomarkers for Merkel cell carcinoma: Pitfalls and opportunities., PMID:31218705
Circulating and tissue IMP3 levels are correlated with poor survival in renal cell carcinoma., PMID:30650187
Upregulation of insulin-like growth factor II mRNA-binding protein 3 (IMP3) has negative prognostic impact on early invasive (pT1) adenocarcinoma of the esophagus., PMID:29974234
Anti-cytoplasmic Autoantibodies in Hodgkin's Lymphoma., PMID:28164609
IMP3 Immunohistochemical Expression Remains Consistent Among All Grades of Gastrointestinal Neuroendocrine Tumors., PMID:27438513
Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target., PMID:26244168
[Preparation and identification of the polyclonal antibody against human insulin-like growth factor 2 mRNA-binding protein 3]., PMID:25854578
The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer., PMID:25068994
Possible involvement of insulin-like growth factor 2 mRNA-binding protein 3 in zebrafish oocyte maturation as a novel cyclin B1 mRNA-binding protein that represses the translation in immature oocytes., PMID:24735541
Autoantibody detection to tumor-associated antigens of P53, IMP1, P16, cyclin B1, P62, C-myc, Survivn, and Koc for the screening of high-risk subjects and early detection of esophageal squamous cell carcinoma., PMID:24147952
Utility of ProExC and IMP3 immunocytochemical staining in atypical glandular cells of undetermined significance in liquid-based cervical cytology., PMID:23904388
Expression of insulin-like growth factor II mRNA-binding protein 3 in human esophageal adenocarcinoma and its precursor lesions., PMID:21809994
Peptides derived from human insulin-like growth factor-II mRNA binding protein 3 can induce human leukocyte antigen-A2-restricted cytotoxic T lymphocytes reactive to cancer cells., PMID:21087352
IMP3/L523S, a novel immunocytochemical marker that distinguishes benign and malignant cells: the expression profiles of IMP3/L523S in effusion cytology., PMID:20060157
IMP3 expression is correlated with histologic grade of lung adenocarcinoma., PMID:20004948
Diagnostic utility of IMP3 in segregating metastatic melanoma from benign nevi in lymph nodes., PMID:19734845
IMP3 is a novel biomarker for triple negative invasive mammary carcinoma associated with a more aggressive phenotype., PMID:19695680
Insulin-like growth factor mRNA binding protein 3 (IMP3) is differentially expressed in benign and malignant follicular patterned thyroid tumors., PMID:19449140
Expression of K homology domain containing protein (KOC) in pancreatic cytology with corresponding histology., PMID:19365962
Evaluation of tumour-associated antigen (TAA) miniarray in immunodiagnosis of colon cancer., PMID:19140877
IGF2BP3 (IMP3) expression is a marker of unfavorable prognosis in ovarian carcinoma of clear cell subtype., PMID:19136932
An oncofetal protein IMP3: a new molecular marker for the detection of esophageal adenocarcinoma and high-grade dysplasia., PMID:19047899
Merkel cell carcinoma expresses K homology domain-containing protein overexpressed in cancer similar to other high-grade neuroendocrine carcinomas., PMID:18835627
KOC (K homology domain containing protein overexpressed in cancer) and S100A4-protein immunoreactivity improves the diagnostic sensitivity of biliary brushing cytology for diagnosing pancreaticobiliary malignancies., PMID:18618724
The oncofetal protein IMP3: a novel biomarker for endometrial serous carcinoma., PMID:18223334
IMP-3 is a novel progression marker in malignant melanoma., PMID:18204432
Utility of anti-L523S antibody in the diagnosis of benign and malignant serous effusions., PMID:18098206
Expression of K homology domain containing protein overexpressed in cancer in pancreatic FNA for diagnosing adenocarcinoma of pancreas., PMID:17924416
Extrapulmonary small cell carcinomas express K homology domain containing protein overexpressed in cancer, but carcinoid tumors do not., PMID:17521698
High-grade neuroendocrine carcinomas of the lung express K homology domain containing protein overexpressed in cancer but carcinoid tumors do not., PMID:17316760
IMP3 is a novel biomarker for adenocarcinoma in situ of the uterine cervix: an immunohistochemical study in comparison with p16(INK4a) expression., PMID:17192788
KOC (K homology domain containing protein overexpressed in cancer): a novel molecular marker that distinguishes between benign and malignant lesions of the pancreas., PMID:15644775
Autoimmune responses to mRNA binding proteins p62 and Koc in diverse malignancies., PMID:11465943
For research use only. Not for human or drug use.
