Catalog No.
RHH01301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, WB: 1:1000-1:2000
Target
Early endosome antigen 1, EEA1, MST105, ZFYVE2, Early endosome antigen 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q15075
Applications
IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1C49
Dual roles of CXCR4 (C-X-C motif chemokine receptor 4) in promoting entry of ebolavirus and targeting excessive glycoprotein for reticulophagic degradation to facilitate viral fitness., PMID:40223186
Massive entry of BK Polyomavirus induces transient cytoplasmic vacuolization of human renal proximal tubule epithelial cells., PMID:39570904
Comprehensive knockout analysis of the RAB family small GTPases reveals an overlapping role of RAB2 and RAB14 in autophagosome maturation., PMID:38953305
Endosomal protein expression of γ1-adaptin is associated with tumor growth activity and relapse-free survival in breast cancer., PMID:38265632
Modifications of the endosomal compartment in fibroblasts from sporadic Alzheimer's disease patients are associated with cognitive impairment., PMID:36788216
Localization of Chicken Rab22a in Cells and Its Relationship to BF or Ii Molecules and Genes., PMID:36766276
Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry., PMID:36638888
Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq., PMID:36300623
Regulation of TLR10 Expression and Its Role in Chemotaxis of Human Neutrophils., PMID:35613551
Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq., PMID:35350199
Albumin Expands Albumin Reabsorption Capacity in Proximal Tubule Epithelial Cells through a Positive Feedback Loop between AKT and Megalin., PMID:35055044
Quantitative correlative microscopy reveals the ultrastructural distribution of endogenous endosomal proteins., PMID:34817533
Interruption of endolysosomal trafficking leads to stroke brain injury., PMID:34363809
Src is essential for the endosomal delivery of the FGFR4 signaling complex in hepatocellular carcinoma., PMID:33794926
SLAMF1 signaling induces Mycobacterium tuberculosis uptake leading to endolysosomal maturation in human macrophages., PMID:32991756
An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells., PMID:32897127
Glucosamine-NISV delivers antibody across the blood-brain barrier: Optimization for treatment of encephalitic viruses., PMID:32512014
Vps35 Deficiency Impairs Cdk5/p35 Degradation and Promotes the Hyperphosphorylation of Tau Protein in Retinal Ganglion Cells., PMID:31995153
Immunoreactivities for hepcidin, ferroportin, and hephaestin in astrocytes and choroid plexus epithelium of human brains., PMID:31755170
Clostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL., PMID:31703116
Monitoring Intracellular Routing of Internalized Antigens by Immunofluorescence Microscopy., PMID:31147944
Decorin antagonizes corneal fibroblast migration via caveolae-mediated endocytosis of epidermal growth factor receptor., PMID:30611736
ATG5 is required for B cell polarization and presentation of particulate antigens., PMID:30196744
Proteomics reveals novel protein associations with early endosomes in an epidermal growth factor-dependent manner., PMID:29523688
Apical-to-basolateral transepithelial transport of cow's milk caseins by intestinal Caco-2 cell monolayers: MS-based quantitation of cellularly degraded α- and β-casein fragments., PMID:29490044
Intravesicular epidermal growth factor receptor subject to retrograde trafficking drives epidermal growth factor-dependent migration., PMID:29464085
Internalization and localization of basal insulin peglispro in cells., PMID:28576743
Localization of the human neonatal Fc receptor (FcRn) in human nasal epithelium., PMID:26634928
Rendomab B4, a monoclonal antibody that discriminates the human endothelin B receptor of melanoma cells and inhibits their migration., PMID:27390909
Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes., PMID:27226631
Functional Specialty of CD40 and Dendritic Cell Surface Lectins for Exogenous Antigen Presentation to CD8(+) and CD4(+) T Cells., PMID:27077111
Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport., PMID:26949061
Anti-early endosome antigen 1 autoantibodies were detected in a pemphigus-like patient but not in the majority of pemphigus diseases., PMID:26909655
Subcellular trafficking of guanylyl cyclase/natriuretic peptide receptor-A with concurrent generation of intracellular cGMP., PMID:26374856
Membrane associated cancer-oocyte neoantigen SAS1B/ovastacin is a candidate immunotherapeutic target for uterine tumors., PMID:26327203
Atopic donor status does not influence the uptake of the major grass pollen allergen, Phl p 5, by dendritic cells., PMID:26055335
Celecoxib increases EGF signaling in colon tumor associated fibroblasts, modulating EGFR expression and degradation., PMID:25987127
Renal type a intercalated cells contain albumin in organelles with aldosterone-regulated abundance., PMID:25874770
Trafficking of Estrella lausannensis in human macrophages., PMID:25857735
[Analysis of vesicle subpopulations carrying early endosomal autoantigen EEA1]., PMID:25711083
HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC)., PMID:25484075
Altered dynamics of a lipid raft associated protein in a kidney model of Fabry disease., PMID:24215843
Early Endosome Antigen 1 (EEA1) decreases in macrophages infected with Paracoccidioides brasiliensis., PMID:23566224
The roles of complement receptor 3 and Fcγ receptors during Leishmania phagosome maturation., PMID:23543768
Monitoring the intracellular routing of internalized antigens by immunofluorescence microscopy., PMID:23329500
The Na(+)/H (+) exchanger NHE5 is sorted to discrete intracellular vesicles in the central and peripheral nervous systems., PMID:23224898
The use of quantum dots for immunochemistry applications., PMID:22791432
The Gαq/11 proteins contribute to T lymphocyte migration by promoting turnover of integrin LFA-1 through recycling., PMID:22701657
Astrocytes acquire morphological and functional characteristics of ependymal cells following disruption of ependyma in hydrocephalus., PMID:22576081
Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation., PMID:21860028
For research use only. Not for human or drug use.
