Catalog No.
YHC17601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln21-Asp728
Predicted molecular weight
80.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05556
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MSK12, VLA-4 subunit beta, CD29, Integrin beta-1, ITGB1, FNRB, MDF2, GPIIA, Glycoprotein IIa, Fibronectin receptor subunit beta
N-Glycosylation as a Key Requirement for the Positive Interaction of Integrin and uPAR in Glioblastoma., PMID:40508119
Isolation and Characterization of Articular Cartilage-Derived Cells Obtained by Arthroscopic Cartilage Biopsy from Non-Osteoarthritic Patients., PMID:40498006
Matrix Stiffness Promotes Invasion and Metastasis of Hepatocellular Carcinoma via a New Mechanoresponsive SCD1/HMMR Pathway., PMID:40497374
CyTOF reveals platelet subtype changes predicting the efficacy of combined immunotherapy and targeted therapy in liver cancer., PMID:40496869
Cellular dynamics and signalling mechanisms in dentine repair: A narrative review., PMID:40491185
Mechanisms of tumor heterogeneity in TACE-resistant liver cancer: Insights from single-cell and whole-exome sequencing., PMID:40489756
Semaphorin 7A Induces Liver Inflammation and Promotes Parenteral Nutrition-Associated Cholestasis via ITGβ1/NF-κB Pathway., PMID:40483769
SEMA7A: A glycoprotein with therapeutic potential in inflammatory diseases and tumor development., PMID:40480556
Thrombospondin-1 mitigates osteoarthritis progression by inhibiting mechanical stress-induced chondrocyte ferroptosis via the integrin/YAP pathway., PMID:40475787
Tenogenic potential of tendon-derived mesenchymal stem cells isolated post-mortem: Impact of cryopreservation., PMID:40472780
Matrix stiffness-induced IKBKE and MAPK8 signaling drives a phenotypic switch from DCIS to invasive breast cancer., PMID:40468448
Aberrant Fibro-Adipogenic Progenitor Subpopulations Drive Volumetric Muscle Loss-Induced Fibrosis., PMID:40463024
Substrate stiffness modifies gene expression and transcriptional response of equine endometrial fibroblasts to TGF-β1., PMID:40460762
MFAP4 Deficiency Attenuates Liver Fibrosis by Regulating Hepatic Stellate Cell Fate through Inhibition of the FAK/PI3K/NFκB Signaling Pathway., PMID:40449846
Reln-Dab1 pathway mitigates retinal ganglion cell apoptosis in retinal ischemia-reperfusion injury., PMID:40442071
Disruption of Retriever Function Impacts Retrograde Trafficking From Endosomes., PMID:40439270
The Serine/Threonine Kinase NDR2 Regulates Integrin Signaling, Synapse Formation, and Synaptic Plasticity in the Hippocampus., PMID:40439020
Recombinant human fibronectin segment (rhFN1024) hydrogel carried hPDLSCs to repair diabetic trauma by activated NF-κB signaling pathway., PMID:40438201
Enhanced migration and adhesion protein expression by polyethylene glycol 4-modified SVVYGLR peptide in an in vitro human gingival fibroblast wound healing model., PMID:40421822
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells., PMID:40419795
Effects of dietary grape seed proanthocyanidin extract supplementation on muscle water-holding capacity of finishing pigs., PMID:40412284
Mechanical signal modulates prostate cancer immune escape by USP8-mediated ubiquitination-dependent degradation of PD-L1 and MHC-1., PMID:40410130
Inhibitory effects of β-galactoside α2,6-sialyltransferase 1 on the Hippo pathway in breast cancer cells., PMID:40409546
Daidzein alleviates CCl4- and BDL-induced liver fibrosis via suppressing the integrin alphaVbeta1/YAP signaling., PMID:40407304
The impact of Talin2, a signaling protein regulating the focal adhesion complex, on asthma., PMID:40401633
Hippocampal Extracellular Matrix Protein Laminin β1 Regulates Neuropathic Pain and Pain-Related Cognitive Impairment., PMID:40397355
Human CD29+/CD56+ myogenic progenitors display tenogenic differentiation potential and facilitate tendon regeneration., PMID:40387093
MiR-124-3p inhibits proliferation, migration, and epithelial-mesenchymal transformation in gastric cancer by targeting ITGB1., PMID:40385048
Incorporation of graphene oxide into collagenous biomaterials attenuates scar-forming phenotype transition of reactive astrocytes in vitro., PMID:40383237
Load activated FGFR and beta1 integrins target distinct chondrocyte mechano-response genes., PMID:40379111
IGFBP3 enhances adipose-derived stem cell function in soft tissue injury repair via ITGB1 and ERK pathway activation., PMID:40369223
Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast., PMID:40363772
Interaction of Serratia proteamaculans with Integrins Activates Invasion-Promoting Signaling Pathways., PMID:40362195
Donor adipose-derived stromal cells are vasoprotectant but unable to revert acute rejection in rodent vascularized composite allotransplants., PMID:40356930
[Mechanism of icariin in promoting osteogenic differentiation of BMSCs and improving bone metabolism disorders through caveolin-1/Hippo signaling pathway]., PMID:40350837
Silencing HMGB1 secretion inhibited EV71-induced blood-brain barrier dysfunction and neural inflammation by depressing astrocyte activation via sHh signal blockage., PMID:40349912
Extracellular matrix induces trophoblast HtrA4 expression: Implications for the pathogenesis of placenta accreta spectrum., PMID:40334386
Expression of Prooncogenic Nuclear Receptor 4A (NR4A)-Regulated Genes β1-Integrin and G9a Inhibited by Dual NR4A1/2 Ligands., PMID:40332813
TNF induces catabolism in human cartilaginous endplate cells in 3D agarose culture under dynamic compression., PMID:40328789
Binding of collagen I to integrins alleviates UVB-caused mitochondrial disorders in human keratinocytes HaCaT through enhancement of F-actin polymerization., PMID:40328195
TWEAK regulates the functions of hair follicle stem cells via the Fn14-Wnt/β-catenin-CXCR4 signalling axis., PMID:40325995
Delivery of Itgb1-siRNA by triptolide-modified and anti-Flt1 peptide-guided ionizable cationic LNPs for targeted therapy of corneal neovascularization., PMID:40324532
Structural and Functional Differences of Rhodostomin and Echistatin in Integrin Recognition and Biological Implications., PMID:40318183
Activated alpha 9 integrin expression enables sensory pathway reconstruction after spinal cord injury., PMID:40317093
Merocytophagy is an integrin-stabilized macrophage response to microbes reliant on Syk signaling., PMID:40313956
MOSPD2 regulates the activation state of αLβ2 integrin to control monocyte migration: applicability for treatment of chronic inflammatory diseases., PMID:40312574
Extracellular Vesicle Marker Changes Associated With Disease Activity in Relapsing-Remitting Multiple Sclerosis., PMID:40300121
Extracellular Matrix Microstructures Modulate Hepatic Methionine Cycle and Methylations., PMID:40298277
Bimodal genomic approach predicting Semaphorin 7A (SEMA7A) as prognostic biomarker in adrenocortical carcinoma., PMID:40291702
Exploring STEAP1 Expression in Prostate Cancer Cells in Response to Androgen Deprivation and in Small Extracellular Vesicles., PMID:40287951
For research use only. Not for human or drug use.
