Catalog No.
RHD59301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
CFL, CFL1, Cofilin 1, Cofilin, Cofilin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P23528
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1B55
A high affinity Sybody blocks Cofilin-1 binding to F-actin in vitro and in cancer cells., PMID:40064451
Serum anti-CFL1, anti-EZR, and anti-CYPA autoantibody as diagnostic markers in ovarian cancer., PMID:38684875
Complex changes in serum protein levels in COVID-19 convalescents., PMID:38396092
Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions., PMID:36937574
The combination of positive anti‑WDR1 antibodies with negative anti‑CFL1 antibodies in serum is a poor prognostic factor for patients with esophageal carcinoma., PMID:36875818
Low anti-CFL1 antibody with high anti-ACTB antibody is a poor prognostic factor in esophageal squamous cell carcinoma., PMID:35780443
Inhibition of Cathepsin B and SAPC Secreted by HIV-Infected Macrophages Reverses Common and Unique Apoptosis Pathways., PMID:34994563
Cofilin1-driven actin dynamics controls migration of thymocytes and is essential for positive selection in the thymus., PMID:31974112
Nogo-A promotes inflammatory heat hyperalgesia by maintaining TRPV-1 function in the rat dorsal root ganglion neuron., PMID:30024789
Multiple reaction monitoring targeted LC-MS analysis of potential cell death marker proteins for increased bioprocess control., PMID:29607450
CD74 interacts with CD44 and enhances tumorigenesis and metastasis via RHOA-mediated cofilin phosphorylation in human breast cancer cells., PMID:27626171
Effect of omega-3 polyunsaturated fatty acids on the cytoskeleton: an open-label intervention study., PMID:25971815
Chemokine receptor 7 promotes tumor migration and invasiveness via the RhoA/ROCK pathway in metastatic squamous cell carcinoma of the head and neck., PMID:25434638
Enhanced cellular radiosensitivity induced by cofilin-1 over-expression is associated with reduced DNA repair capacity., PMID:23362981
B cell receptor-induced Ca2+ mobilization mediates F-actin rearrangements and is indispensable for adhesion and spreading of B lymphocytes., PMID:23362305
Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching morphogenesis., PMID:21060807
Regulation of AMPA receptor channels and synaptic plasticity by cofilin phosphatase Slingshot in cortical neurons., PMID:20442266
Decreased cofilin1 expression is important for compaction during early mouse embryo development., PMID:19751773
Ca(2+) influx through P2X receptors induces actin cytoskeleton reorganization by the formation of cofilin rods in neurites., PMID:17993279
The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12., PMID:17452627
Palladin regulates cell and extracellular matrix interaction through maintaining normal actin cytoskeleton architecture and stabilizing beta1-integrin., PMID:17115415
Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells., PMID:15548599
The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics., PMID:11809832
A putative plant homolog of the yeast beta-1,3-glucan synthase subunit FKS1 from cotton (Gossypium hirsutum L.) fibers., PMID:11469587
Characterization of human muscle type cofilin (CFL2) in normal and regenerating muscle., PMID:11422377
For research use only. Not for human or drug use.
