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Anti-SMARCB1 Antibody (R1A54)

Catalog #:   RHG30001 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IP, WB
Accession: Q12824
Overview

Catalog No.

RHG30001

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IP: 1:20-1:50, WB: 1:1000-1:2000

Target

SMARCB1, BAF47, hSNF5, INI1, RDT, RTPS1, Sfh1p, SMARCB1, SNF5 homolog, SNF5L1, Snr1, SWI/SNF comp, SMARCB1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q12824

Applications

IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4 ℃ short term (1-2 weeks). Store at -20 ℃ 12 months. Store at -80 ℃ long term.

Clone ID

R1A54

Data Image
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    Western blot analysis of SNF5 in (1) HeLa cell lysate; (2) K562 cell lysate.
References

Immunohistochemical analysis of 147 cases of low-grade endometrial stromal sarcoma: refining the immunohistochemical profile of LG-ESS on a large, molecularly confirmed series., PMID:39836188

The genetics and epidemiology of N- and O-immunoglobulin A glycomics., PMID:39123268

Myoepithelial tumors of soft tissue and bone in children and young adults: A clinicopathologic study of 40 cases occurring in patients ≤ 21 Years of age., PMID:38782103

A Phase 2 Trial of Talazoparib and Avelumab in Genomically Defined Metastatic Kidney Cancer., PMID:37945488

New classification and approaches to the treatment of schwannomatosis., PMID:37830475

Brain and Spinal Cord Tumors of Embryonic Origin., PMID:37452947

Genetic mutations in HER2-positive breast cancer: possible association with response to trastuzumab therapy., PMID:37202799

Characterization of Switch/Sucrose Nonfermenting Complex Proteins and Nestin Expression in a Cohort of Pediatric Central Nervous System Tumors., PMID:37036408

How I treat recurrent pediatric high-grade glioma (pHGG): a Europe-wide survey study., PMID:36720762

Malignant undifferentiated and rhabdoid tumors of the gastroesophageal junction and esophagus with SMARCA4 loss: a case series., PMID:36549598

Sustained response to bevacizumab in a patient with mosaic neurofibromatosis type 2 carrying the NF2:c.784C>T p.(Arg262*) variant., PMID:35445657

Pembrolizumab as maintenance therapy for malignant rhabdoid tumor., PMID:35278029

Identification of novel SSX1 fusions in synovial sarcoma., PMID:34504309

Diagnostic Immunohistochemistry of Soft Tissue and Bone Tumors: An Update on Biomarkers That Correlate with Molecular Alterations., PMID:33921435

Discovery and Validation of Serum Autoantibodies Against Tumor-Associated Antigens as Biomarkers in Gastric Adenocarcinoma Based on the Focused Protein Arrays., PMID:33346593

Analysis of 24 cases of epithelioid glioblastoma: Experience from a tertiary centre of North India., PMID:33341703

Nucleoporin 210 Serves a Key Scaffold for SMARCB1 in Liver Cancer., PMID:33239431

Aggressive Hematopoietic Malignancy Characterized by Biallelic Loss of SMARCB1., PMID:33163846

Genomic and epigenomic insights into the origin, pathogenesis, and clinical behavior of mantle cell lymphoma subtypes., PMID:32584970

Xanthogranulomatous epithelial tumor: report of 6 cases of a novel, potentially deceptive lesion with a predilection for young women., PMID:32415263

SWI/SNF protein and claudin-4 expression in anaplastic carcinomas arising in mucinous tumours of the ovary and retroperitoneum., PMID:32268438

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases., PMID:32128391

Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma., PMID:31906887

Sinonasal Undifferentiated Carcinoma (SNUC): From an Entity to Morphologic Pattern and Back Again-A Historical Perspective., PMID:31876536

Clinicopathologic study of deciduoid mesothelioma using SMARCB1/INI1 immunohistochemistry and fluorescence in situ hybridization., PMID:31445842

SMARCB1- and vimentin-positive esophageal carcinoma with undifferentiated components, rhabdoid features, and a good prognosis: a case report., PMID:30649642

SWI/SNF protein expression status in fumarate hydratase-deficient renal cell carcinoma: immunohistochemical analysis of 32 tumors from 28 patients., PMID:29689242

Loss of Expression of a Novel Chromatin Remodeler SMARCA1 in Soft Tissue Sarcoma., PMID:31093468

A Diagnostic Pitfall: Atypical Teratoid Rhabdoid Tumor Versus Dedifferentiated/Poorly Differentiated Chordoma: Analysis of a Mono-institutional Series., PMID:28777153

Evaluation of a novel approach to circulating tumor cell isolation for cancer gene panel analysis in patients with breast cancer., PMID:28521409

Insulin-like growth factor 2 axis supports the serum-independent growth of malignant rhabdoid tumor and is activated by microenvironment stress., PMID:28521298

Genomic characteristics of trastuzumab-resistant Her2-positive metastatic breast cancer., PMID:28247034

Oncogenic roles of SMARCB1/INI1 and its deficient tumors., PMID:28109176

Loss of expression of the SWI/SNF complex is a frequent event in undifferentiated/dedifferentiated urothelial carcinoma of the urinary tract., PMID:27339451

Diagnostic Approach to Synovial Sarcoma of the Head and Neck Illustrated by Two Cases Arising in the Face and Oral Cavity., PMID:27195266

Type 1 papillary renal cell carcinoma in a patient with schwannomatosis: Mosaic versus loss of SMARCB1 expression in respectively schwannoma and renal tumor cells., PMID:26799435

Lumbar spinal atypical teratoid rhabdoid tumor., PMID:26234633

Beware of immunohistochemistry--report of a cytokeratin-, desmin- and INI-1-negative pelvic desmoplastic small round cell tumor in a 51 year old woman., PMID:25755805

Clinical and genetic features of rhabdoid tumors of the heart registered with the European Rhabdoid Registry (EU-RHAB)., PMID:24972932

Premature termination of SMARCB1 translation may be followed by reinitiation in schwannomatosis-associated schwannomas, but results in absence of SMARCB1 expression in rhabdoid tumors., PMID:24740647

Generation of a monoclonal antibody for INI1/hSNF5/BAF47., PMID:24555937

SMARCB1 involvement in the development of leiomyoma in a patient with schwannomatosis., PMID:24525513

Malignant melanotic schwannian tumor: a clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of "melanotic schwannoma"., PMID:24145644

ERG and FLI1 protein expression in epithelioid sarcoma., PMID:24072183

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers., PMID:23382691

The clinical significance of SWI/SNF complex in pancreatic cancer., PMID:23229642

Specificity and sensitivity of INI-1 labeling in epithelioid sarcoma. Loss of INI1 expression as a frequent immunohistochemical event in synovial sarcoma., PMID:23161234

p63, CK7, PAX8 and INI-1: an optimal immunohistochemical panel to distinguish poorly differentiated urothelial cell carcinoma from high-grade tumours of the renal collecting system., PMID:22260386

Immunohistochemical analysis of SMARCB1/INI-1 expression in collecting duct carcinoma., PMID:21705046

Nonsense mutation and inactivation of SMARCA4 (BRG1) in an atypical teratoid/rhabdoid tumor showing retained SMARCB1 (INI1) expression., PMID:21566516

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-SMARCB1 Antibody (R1A54) [RHG30001]
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